kynurenic acid has been researched along with Hypotension in 8 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess whether systemic delivery of kynurenic acid improves the outcomes of heatstroke in rats." | 7.77 | Kynurenic acid attenuates multiorgan dysfunction in rats after heatstroke. ( Chen, RF; Chen, SH; Hsieh, JH; Hsieh, YC; Lin, MT; Yeh, YS, 2011) |
| "To assess whether systemic delivery of kynurenic acid improves the outcomes of heatstroke in rats." | 3.77 | Kynurenic acid attenuates multiorgan dysfunction in rats after heatstroke. ( Chen, RF; Chen, SH; Hsieh, JH; Hsieh, YC; Lin, MT; Yeh, YS, 2011) |
| "In the present study, we investigated the effects of pretreatment with NG-nitro-L-arginine methyl ester (L-NAME) (nitric oxide synthase inhibitor) injected intravenously (IV) on the hypotension, bradycardia, and vasodilation produced by moxonidine (alpha2-adrenergic/imidazoline receptor agonist) injected into the fourth brain ventricle (4th V) in rats submitted to acute hypertension that results from baroreflex blockade by bilateral injections of kynurenic acid (kyn, glutamatergic receptor antagonist) into the nucleus of the solitary tract (NTS) or in normotensive rats." | 3.73 | Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide. ( Colombari, E; Menani, JV; Moreira, TS; Sato, MA; Takakura, AC, 2006) |
| "Plasma vasopressin (AVP) levels were measured at rest (mean arterial pressure 80-85 mmHg) and during hypotension (mean arterial pressure 38-45 mmHg) induced by ganglionic blockade (trimethaphan) in halothane-anaesthetized respirated rats with end-tidal pCO2 maintained at 34-40 mmHg." | 3.67 | Baroreceptor-independent medullary mechanism for release of vasopressin during hypotension in rats. ( Baertschi, AJ; Guyenet, PG; Hashemzadeh-Gargari, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, Y | 1 |
| Wu, YS | 1 |
| Chen, DS | 1 |
| Wang, MM | 1 |
| Wang, WZ | 1 |
| Yuan, WJ | 1 |
| Mandel, DA | 1 |
| Schreihofer, AM | 1 |
| Cardoso, LM | 1 |
| Colombari, DS | 1 |
| Menani, JV | 2 |
| Toney, GM | 1 |
| Chianca, DA | 1 |
| Colombari, E | 2 |
| Hsieh, YC | 1 |
| Chen, RF | 1 |
| Yeh, YS | 1 |
| Lin, MT | 1 |
| Hsieh, JH | 1 |
| Chen, SH | 1 |
| Korim, WS | 1 |
| Ferreira-Neto, ML | 1 |
| Pedrino, GR | 1 |
| Pilowsky, PM | 1 |
| Cravo, SL | 1 |
| Blair, ML | 1 |
| Mickelsen, D | 1 |
| Moreira, TS | 1 |
| Takakura, AC | 1 |
| Sato, MA | 1 |
| Hashemzadeh-Gargari, H | 1 |
| Baertschi, AJ | 1 |
| Guyenet, PG | 1 |
8 other studies available for kynurenic acid and Hypotension
| Article | Year |
|---|---|
Microinjection of salusin-beta into the nucleus tractus solitarii inhibits cardiovascular function by suppressing presympathetic neurons in rostral ventrolateral medulla in rats.
Topics: Animals; Baroreflex; Bradycardia; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonist | 2015 |
Glutamatergic inputs to the CVLM independent of the NTS promote tonic inhibition of sympathetic vasomotor tone in rats.
Topics: Animals; Baroreflex; Blood Pressure; Blood Vessels; Disease Models, Animal; Excitatory Amino Acid An | 2008 |
Cardiovascular responses to hydrogen peroxide into the nucleus tractus solitarius.
Topics: Amitrole; Anesthesia; Animals; Ascorbic Acid; Blood Pressure; Bradycardia; Cardiovascular System; Ch | 2009 |
Kynurenic acid attenuates multiorgan dysfunction in rats after heatstroke.
Topics: Animals; Apoptosis; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Heat | 2011 |
Interaction of medullary P2 and glutamate receptors mediates the vasodilation in the hindlimb of rat.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Hindlimb; Hypotension; Kynurenic Acid; Male; Rats; | 2012 |
Activation of lateral parabrachial nucleus neurons restores blood pressure and sympathetic vasomotor drive after hypotensive hemorrhage.
Topics: Animals; Blood Pressure; Hemorrhage; Hypotension; Ibotenic Acid; Kynurenic Acid; Male; Neurons; Pons | 2006 |
Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide.
Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradycardia; Drug Interactions; Endoth | 2006 |
Baroreceptor-independent medullary mechanism for release of vasopressin during hypotension in rats.
Topics: Animals; Arginine Vasopressin; Chemoreceptor Cells; Hypotension; Kynurenic Acid; Male; Medulla Oblon | 1988 |