kynurenic acid has been researched along with Glaucoma in 2 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been shown that a possible pathogenetic mechanism of neurodegeneration in the mouse model of glaucoma (DBA/2J) may be an alteration of kynurenic acid (KYNA) in the retina." | 8.02 | Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma. ( Avitabile, T; Choragiewicz, T; Fiedorowicz, M; Grieb, P; Kamińska, A; Kocki, T; Nowakowska, D; Rejdak, R; Toro, MD; Turski, WA; Wertejuk, K; Wełniak-Kaminska, M; Zweifel, S, 2021) |
| "It has been shown that a possible pathogenetic mechanism of neurodegeneration in the mouse model of glaucoma (DBA/2J) may be an alteration of kynurenic acid (KYNA) in the retina." | 4.02 | Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma. ( Avitabile, T; Choragiewicz, T; Fiedorowicz, M; Grieb, P; Kamińska, A; Kocki, T; Nowakowska, D; Rejdak, R; Toro, MD; Turski, WA; Wertejuk, K; Wełniak-Kaminska, M; Zweifel, S, 2021) |
| "Glaucoma is an optic neuropathy and involves the progressive degeneration of retinal ganglion cells (RGCs), which leads to blindness in patients." | 1.56 | Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice. ( Houck, JA; Johnson, GC; MacLean, PS; Nagaraj, RH; Nahomi, RB; Nam, MH; Pantcheva, MB; Rakete, S; Rankenberg, J; Stankowska, DL, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nahomi, RB | 1 |
| Nam, MH | 1 |
| Rankenberg, J | 1 |
| Rakete, S | 1 |
| Houck, JA | 1 |
| Johnson, GC | 1 |
| Stankowska, DL | 1 |
| Pantcheva, MB | 1 |
| MacLean, PS | 1 |
| Nagaraj, RH | 1 |
| Fiedorowicz, M | 1 |
| Choragiewicz, T | 1 |
| Turski, WA | 1 |
| Kocki, T | 1 |
| Nowakowska, D | 1 |
| Wertejuk, K | 1 |
| Kamińska, A | 1 |
| Avitabile, T | 1 |
| Wełniak-Kaminska, M | 1 |
| Grieb, P | 1 |
| Zweifel, S | 1 |
| Rejdak, R | 1 |
| Toro, MD | 1 |
2 other studies available for kynurenic acid and Glaucoma
| Article | Year |
|---|---|
Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Excitatory Amino Acid Antagonists; | 2020 |
Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma.
Topics: Animals; Biomarkers; Disease Models, Animal; Disease Susceptibility; Genetic Diseases, Inborn; Glauc | 2021 |