kynurenic acid has been researched along with Genetic Predisposition in 3 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The kynurenine pathway metabolite kynurenic acid (KYNA), modulating glutamatergic and cholinergic neurotransmission, is increased in cerebrospinal fluid (CSF) of patients with schizophrenia or bipolar disorder type 1 with psychotic features." | 3.80 | The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression. ( Backlund, L; Cichon, S; Engberg, G; Erhardt, S; Frisén, L; Landén, M; Lavebratt, C; Nikamo, P; Olsson, S; Osby, U; Priebe, L; Schalling, M; Sellgren, C; Träskman-Bendz, L; Vawter, MP, 2014) |
| "Several lines of evidence suggest that metabolic changes in the kynurenic acid (KYNA) pathway are related to the etiology of schizophrenia." | 3.73 | Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population. ( Aoyama, N; Ikeda, M; Inada, T; Ishihara, R; Iwata, N; Ji, X; Kinoshita, Y; Kitajima, T; Maeno, N; Miura, H; Ozaki, N; Saito, S; Suzuki, T; Takahashi, N; Yamanouchi, Y; Yoshida, K, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lavebratt, C | 1 |
| Olsson, S | 1 |
| Backlund, L | 1 |
| Frisén, L | 1 |
| Sellgren, C | 1 |
| Priebe, L | 1 |
| Nikamo, P | 1 |
| Träskman-Bendz, L | 1 |
| Cichon, S | 1 |
| Vawter, MP | 1 |
| Osby, U | 1 |
| Engberg, G | 1 |
| Landén, M | 1 |
| Erhardt, S | 1 |
| Schalling, M | 1 |
| Aoyama, N | 1 |
| Takahashi, N | 1 |
| Saito, S | 1 |
| Maeno, N | 1 |
| Ishihara, R | 1 |
| Ji, X | 1 |
| Miura, H | 1 |
| Ikeda, M | 1 |
| Suzuki, T | 1 |
| Kitajima, T | 1 |
| Yamanouchi, Y | 1 |
| Kinoshita, Y | 1 |
| Yoshida, K | 1 |
| Iwata, N | 1 |
| Inada, T | 1 |
| Ozaki, N | 1 |
| Fitzjohn, SM | 1 |
| Morton, RA | 1 |
| Kuenzi, F | 1 |
| Rosahl, TW | 1 |
| Shearman, M | 1 |
| Lewis, H | 1 |
| Smith, D | 1 |
| Reynolds, DS | 1 |
| Davies, CH | 1 |
| Collingridge, GL | 1 |
| Seabrook, GR | 1 |
3 other studies available for kynurenic acid and Genetic Predisposition
| Article | Year |
|---|---|
The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression.
Topics: Adult; Aged; Alleles; Bipolar Disorder; Case-Control Studies; Cell Line; Female; Gene Expression; Ge | 2014 |
Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population.
Topics: Aged; Case-Control Studies; Chi-Square Distribution; Chromosomes, Human, Pair 1; Epigenesis, Genetic | 2006 |
Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Electric | 2001 |