kynurenic acid has been researched along with Encephalitis in 7 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Encephalitis: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction." | 1.28 | Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. ( Crowley, JS; Davis, LE; Demitrack, MA; Der, M; Dilling, LA; Elia, J; Heyes, MP; Kruesi, MJ; Lackner, A; Saito, K, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Miyamoto, K | 1 |
| Sujino, T | 1 |
| Harada, Y | 1 |
| Ashida, H | 1 |
| Yoshimatsu, Y | 1 |
| Yonemoto, Y | 1 |
| Nemoto, Y | 1 |
| Tomura, M | 1 |
| Melhem, H | 1 |
| Niess, JH | 1 |
| Suzuki, T | 2 |
| Suzuki, S | 1 |
| Koda, Y | 1 |
| Okamoto, R | 1 |
| Mikami, Y | 1 |
| Teratani, T | 1 |
| Tanaka, KF | 1 |
| Yoshimura, A | 1 |
| Sato, T | 1 |
| Kanai, T | 1 |
| van der Velpen, V | 1 |
| Rosenberg, N | 1 |
| Maillard, V | 1 |
| Teav, T | 1 |
| Chatton, JY | 1 |
| Gallart-Ayala, H | 1 |
| Ivanisevic, J | 1 |
| Kim, YK | 1 |
| Won, E | 1 |
| Erhardt, S | 1 |
| Lim, CK | 1 |
| Linderholm, KR | 1 |
| Janelidze, S | 1 |
| Lindqvist, D | 1 |
| Samuelsson, M | 1 |
| Lundberg, K | 1 |
| Postolache, TT | 1 |
| Träskman-Bendz, L | 1 |
| Guillemin, GJ | 1 |
| Brundin, L | 1 |
| Rejdak, K | 1 |
| Petzold, A | 1 |
| Kocki, T | 1 |
| Kurzepa, J | 1 |
| Grieb, P | 1 |
| Turski, WA | 1 |
| Stelmasiak, Z | 1 |
| Heyes, MP | 2 |
| Saito, K | 2 |
| Major, EO | 1 |
| Milstien, S | 1 |
| Markey, SP | 1 |
| Vickers, JH | 1 |
| Crowley, JS | 1 |
| Davis, LE | 1 |
| Demitrack, MA | 1 |
| Der, M | 1 |
| Dilling, LA | 1 |
| Elia, J | 1 |
| Kruesi, MJ | 1 |
| Lackner, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Kynurenine Pathway Metabolites in Perinatal Depression and Suicidality[NCT02566980] | 209 participants (Actual) | Observational | 2014-10-23 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for kynurenic acid and Encephalitis
| Article | Year |
|---|---|
The influence of stress on neuroinflammation and alterations in brain structure and function in major depressive disorder.
Topics: Animals; Brain; Depressive Disorder, Major; Encephalitis; Humans; Kynurenic Acid; Neurotransmitter A | 2017 |
6 other studies available for kynurenic acid and Encephalitis
| Article | Year |
|---|---|
The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis.
Topics: Animals; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Gastrointestinal Microbiome; Kyn | 2023 |
Sex-specific alterations in NAD+ metabolism in 3xTg Alzheimer's disease mouse brain assessed by quantitative targeted LC-MS.
Topics: Alzheimer Disease; Animals; Chromatography, High Pressure Liquid; Encephalitis; Female; Humans; Kynu | 2021 |
Connecting inflammation with glutamate agonism in suicidality.
Topics: Adult; Aged; Encephalitis; Excitatory Amino Acid Agonists; Female; Follow-Up Studies; Humans; Interl | 2013 |
Astrocytic activation in relation to inflammatory markers during clinical exacerbation of relapsing-remitting multiple sclerosis.
Topics: Acute Disease; Adult; Astrocytes; Biomarkers; Brain; Encephalitis; Female; Gliosis; Humans; Kynureni | 2007 |
A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Topics: 3-Hydroxyanthranilic Acid; Animals; Biopterins; Brain; Encephalitis; Fetus; Indoleamine-Pyrrole 2,3, | 1993 |
Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease.
Topics: Aged; Animals; Brain Diseases; Encephalitis; Female; HIV Infections; Humans; Kynurenic Acid; Kynuren | 1992 |