kynurenic acid has been researched along with Dyskinesia, Drug-Induced in 4 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Kynurenic acid (KYNA) is a neuroactive metabolite that interacts with NMDA, AMPA/kainate and alpha 7 nicotinic receptors." | 1.42 | The inimitable kynurenic acid: the roles of different ionotropic receptors in the action of kynurenic acid at a spinal level. ( Bohar, Z; Horvath, G; Kekesi, G; Pardutz, A; Petrovszki, Z; Safrany-Fark, A; Tar, L; Tuboly, G; Vecsei, L, 2015) |
| "This relationship is altered in Parkinsonism and in levodopa-induced dyskinesias (LID), resulting in an upregulation of corticostriatal glutamatergic function." | 1.33 | Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys. ( Bédard, PJ; Grégoire, L; Guidetti, P; Izzo, E; Rassoulpour, A; Samadi, P; Schwarcz, R, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tuboly, G | 1 |
| Tar, L | 1 |
| Bohar, Z | 1 |
| Safrany-Fark, A | 1 |
| Petrovszki, Z | 1 |
| Kekesi, G | 1 |
| Vecsei, L | 1 |
| Pardutz, A | 1 |
| Horvath, G | 1 |
| Samadi, P | 2 |
| Grégoire, L | 2 |
| Rassoulpour, A | 2 |
| Guidetti, P | 2 |
| Izzo, E | 2 |
| Schwarcz, R | 2 |
| Bédard, PJ | 2 |
| Di Paolo, T | 1 |
| Robertson, RG | 1 |
| Farmery, SM | 1 |
| Sambrook, MA | 1 |
| Crossman, AR | 1 |
4 other studies available for kynurenic acid and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
The inimitable kynurenic acid: the roles of different ionotropic receptors in the action of kynurenic acid at a spinal level.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Disease Models, Animal; Dose-Response | 2015 |
Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Dose- | 2005 |
Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Drug Interactions; Dyskines | 2008 |
Dyskinesia in the primate following injection of an excitatory amino acid antagonist into the medial segment of the globus pallidus.
Topics: Animals; Dyskinesia, Drug-Induced; Globus Pallidus; Kynurenic Acid; Macaca fascicularis; Receptors, | 1989 |