kynurenic acid has been researched along with Drug Withdrawal Symptoms in 14 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The decrease in the seizure threshold for pentylenetetrazole during diazepam withdrawal was inhibited by pretreatment with MK-801 ((+)-5-methyl-10,11-dihydro-5H-dibenzo(a,d)cycloheptan-5,10-imine maleate), 7-chlorokynurenic acid and ifenprodil." | 1.30 | Recovery of decreased seizure threshold for pentylenetetrazole during diazepam withdrawal by NMDA receptor antagonists. ( Misawa, M; Suzuki, T; Tsuda, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 9 (64.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Mechtcheriakov, S | 1 |
| Gleissenthall, GV | 1 |
| Geisler, S | 1 |
| Arnhard, K | 1 |
| Oberacher, H | 1 |
| Schurr, T | 1 |
| Kemmler, G | 1 |
| Unterberger, C | 1 |
| Fuchs, D | 1 |
| Snyder, AE | 1 |
| Salimando, GJ | 1 |
| Winder, DG | 1 |
| Silberman, Y | 1 |
| Morrisett, RA | 1 |
| Cappendijk, SL | 1 |
| de Vries, R | 1 |
| Dzoljic, MR | 1 |
| Liu, YP | 1 |
| Chiang, CP | 1 |
| Tseng, CJ | 1 |
| Huang, NK | 1 |
| Yin, TH | 1 |
| Tung, CS | 2 |
| Tsuda, M | 1 |
| Suzuki, T | 1 |
| Misawa, M | 1 |
| Kotlińska, J | 1 |
| Ivanov, A | 1 |
| Aston-Jones, G | 2 |
| Morgan, PF | 1 |
| Akaoka, H | 1 |
| Rasmussen, K | 3 |
| Krystal, JH | 1 |
| Aghajanian, GK | 2 |
| Grenhoff, J | 1 |
| Svensson, TH | 1 |
1 review available for kynurenic acid and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Afferent effects on locus coeruleus in opiate withdrawal.
Topics: Afferent Pathways; Animals; Cats; Clonidine; Dizocilpine Maleate; Kynurenic Acid; Locus Coeruleus; M | 1991 |
13 other studies available for kynurenic acid and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Tryptophan-kynurenine metabolism during acute alcohol withdrawal in patients with alcohol use disorder: The role of immune activation.
Topics: Alcohol Drinking; Alcoholism; Biomarkers; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Ac | 2022 |
Chronic Intermittent Ethanol and Acute Stress Similarly Modulate BNST CRF Neuron Activity via Noradrenergic Signaling.
Topics: Adrenergic Neurons; Animals; Corticotropin-Releasing Hormone; Ethanol; Excitatory Amino Acid Antagon | 2019 |
Potentiation of N-methyl-D-aspartate receptor-dependent afterdischarges in rat dentate gyrus following in vitro ethanol withdrawal.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Ethanol; Hippocampus; Kynurenic Acid; Magne | 1994 |
Excitatory amino acid receptor antagonists and naloxone-precipitated withdrawal syndrome in morphine-dependent mice.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Mice; Morphine Depend | 1993 |
Morphine withdrawal and schedule-induced polydipsia.
Topics: Animals; Drinking Behavior; Feeding Behavior; Injections, Intraventricular; Kynurenic Acid; Locus Co | 1996 |
Recovery of decreased seizure threshold for pentylenetetrazole during diazepam withdrawal by NMDA receptor antagonists.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Drug I | 1997 |
Attenuation of morphine dependence and withdrawal by glycine B site antagonists in rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Implants; Exc | 2001 |
Local opiate withdrawal in locus coeruleus neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Bari | 2001 |
Is quinolinic acid an endogenous excitotoxin in alcohol withdrawal?
Topics: Alcoholism; Animals; Brain; Humans; Kynurenic Acid; Models, Neurological; Quinolinic Acid; Quinolini | 1991 |
Opiate withdrawal-induced hyperactivity of locus coeruleus neurons is substantially mediated by augmented excitatory amino acid input.
Topics: Amino Acids; Animals; Brain Diseases; Electric Stimulation; Glutamates; Glutamic Acid; Infusion Pump | 1991 |
Excitatory amino acids and morphine withdrawal: differential effects of central and peripheral kynurenic acid administration.
Topics: Amino Acids; Analysis of Variance; Animals; Behavior, Animal; Injections, Intraventricular; Kynureni | 1991 |
Morphine withdrawal responses of rat locus coeruleus neurons are blocked by an excitatory amino-acid antagonist.
Topics: Amino Acids; Animals; Kynurenic Acid; Locus Coeruleus; Male; Morphine; Naloxone; Neurons; Rats; Rats | 1990 |
Withdrawal-induced activation of locus coeruleus neurons in opiate-dependent rats: attenuation by lesions of the nucleus paragigantocellularis.
Topics: Action Potentials; Animals; Kynurenic Acid; Locus Coeruleus; Male; Medulla Oblongata; Morphine; Nalt | 1989 |