kynurenic acid has been researched along with Colitis in 9 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our aim was to determine the extent of inflammatory response and to influence the morphologic changes during the subacute phase of trinitro-benzene sulfonic acid (TNBS)-induced experimental colitis by oral phosphatidylcholine (PC) and N-methyl-D-aspartate (NMDA) receptor antagonist kynurenic acid therapy." | 3.78 | [Comparative study of novel therapeutic possibilities in animal experimental model of inflammatory bowel disease]. ( Boros, M; Erces, D; Ghyczy, M; Kaszaki, J; Kovács, T; Tiszlavicz, L; Tőkés, T; Varga, G; Vécsei, L, 2012) |
| "The inflammatory and motility changes in 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis were studied in anaesthetized Wistar rats following treatment with the natural NMDA-R antagonist kynurenic acid (KynA) or SZR-72, a blood-brain barrier-permeable synthetic KynA analogue." | 3.76 | N-Methyl-D-aspartate receptor antagonism decreases motility and inflammatory activation in the early phase of acute experimental colitis in the rat. ( Boros, M; Erces, D; Fazekas, B; Fülöp, F; Fülöp, M; Kaszaki, J; Kovács, T; Varga, G; Vécsei, L, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Ye, Y | 1 |
| Zhang, X | 1 |
| Su, D | 1 |
| Ren, Y | 1 |
| Cheng, F | 1 |
| Yao, Y | 1 |
| Shi, G | 1 |
| Ji, Y | 1 |
| Chen, S | 1 |
| Shi, P | 1 |
| Dai, L | 1 |
| Su, X | 1 |
| Deng, H | 1 |
| Wang, D | 1 |
| Wang, W | 1 |
| Bing, X | 1 |
| Xu, C | 1 |
| Qiu, J | 1 |
| Shen, J | 1 |
| Huang, J | 1 |
| Li, J | 1 |
| Liu, P | 1 |
| Xie, B | 1 |
| Zhao, L | 1 |
| Xiao, HT | 1 |
| Mu, HX | 1 |
| Huang, T | 1 |
| Lin, ZS | 1 |
| Zhong, LLD | 1 |
| Zeng, GZ | 1 |
| Fan, BM | 1 |
| Lin, CY | 1 |
| Bian, ZX | 1 |
| Zheng, X | 1 |
| Hu, M | 1 |
| Zang, X | 1 |
| Fan, Q | 1 |
| Liu, Y | 1 |
| Che, Y | 1 |
| Guan, X | 1 |
| Hou, Y | 1 |
| Wang, G | 1 |
| Hao, H | 1 |
| Harkin, A | 1 |
| Metghalchi, S | 1 |
| Ponnuswamy, P | 1 |
| Simon, T | 1 |
| Haddad, Y | 1 |
| Laurans, L | 1 |
| Clément, M | 1 |
| Dalloz, M | 1 |
| Romain, M | 1 |
| Esposito, B | 1 |
| Koropoulis, V | 1 |
| Lamas, B | 1 |
| Paul, JL | 1 |
| Cottin, Y | 1 |
| Kotti, S | 1 |
| Bruneval, P | 1 |
| Callebert, J | 1 |
| den Ruijter, H | 1 |
| Launay, JM | 1 |
| Danchin, N | 1 |
| Sokol, H | 1 |
| Tedgui, A | 1 |
| Taleb, S | 1 |
| Mallat, Z | 1 |
| Varga, G | 3 |
| Erces, D | 3 |
| Fazekas, B | 2 |
| Fülöp, M | 1 |
| Kovács, T | 3 |
| Kaszaki, J | 3 |
| Fülöp, F | 2 |
| Vécsei, L | 3 |
| Boros, M | 3 |
| Tőkés, T | 2 |
| Tiszlavicz, L | 2 |
| Ghyczy, M | 1 |
9 other studies available for kynurenic acid and Colitis
| Article | Year |
|---|---|
Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn's colon fibrosis is improved by IFN-γ and kynurenic acid priming through indoleamine 2,3-dioxygenase-1 signaling.
Topics: Animals; Colitis; Crohn Disease; Fibrosis; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammator | 2022 |
GPR35-mediated kynurenic acid sensing contributes to maintenance of gut microbiota homeostasis in ulcerative colitis.
Topics: Animals; Bacteria; Colitis; Colitis, Ulcerative; Gastrointestinal Microbiome; Kynurenic Acid; Rats; | 2023 |
Magnolol, a Natural Polyphenol, Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice.
Topics: Animals; Biphenyl Compounds; Colitis; Dextran Sulfate; Indoleacetic Acids; Indoles; Interleukin-1bet | 2017 |
Kynurenic acid/GPR35 axis restricts NLRP3 inflammasome activation and exacerbates colitis in mice with social stress.
Topics: Animals; Carrier Proteins; Colitis; Colon; Dextran Sulfate; Inflammasomes; Interleukin-1beta; Kynure | 2019 |
A gut instinct for kynurenic acid.
Topics: Animals; Colitis; Inflammasomes; Instinct; Kynurenic Acid; Mice; NLR Family, Pyrin Domain-Containing | 2019 |
Indoleamine 2,3-Dioxygenase Fine-Tunes Immune Homeostasis in Atherosclerosis and Colitis through Repression of Interleukin-10 Production.
Topics: Animals; Atherosclerosis; Colitis; Female; Gene Deletion; Humans; Immunity; Indoleamine-Pyrrole 2,3, | 2015 |
N-Methyl-D-aspartate receptor antagonism decreases motility and inflammatory activation in the early phase of acute experimental colitis in the rat.
Topics: Analysis of Variance; Animals; Blood Pressure; Colitis; Colon; Disease Models, Animal; Excitatory Am | 2010 |
N-methyl-D-aspartate receptor antagonist therapy suppresses colon motility and inflammatory activation six days after the onset of experimental colitis in rats.
Topics: Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Hemodynamics; Interleuki | 2012 |
[Comparative study of novel therapeutic possibilities in animal experimental model of inflammatory bowel disease].
Topics: Administration, Oral; Animals; Biomarkers; Colitis; Disease Models, Animal; Excitatory Amino Acid An | 2012 |