kynurenic acid has been researched along with Colitis, Mucous in 3 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our objectives are to demonstrate whether the kynurenine pathway is activated in diarrhea-type irritable bowel syndrome (IBS-D) patients, and whether the neurotoxic metabolite quinolinic acid (QUIN) is out of balance with the neuroprotective metabolite kynurenic acid (KYNA), and further explore whether this can lead to increase of N-methyl D-aspartate receptor 2B (NMDAR2B) expression in the enteric nervous system and in turn leads to intestinal symptoms and mood disorders." | 7.96 | Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome. ( Bai, Y; Cui, Z; Li, P; Li, Y; Wang, D; Wang, Y; Zhang, J; Zheng, J, 2020) |
| "Our objectives are to demonstrate whether the kynurenine pathway is activated in diarrhea-type irritable bowel syndrome (IBS-D) patients, and whether the neurotoxic metabolite quinolinic acid (QUIN) is out of balance with the neuroprotective metabolite kynurenic acid (KYNA), and further explore whether this can lead to increase of N-methyl D-aspartate receptor 2B (NMDAR2B) expression in the enteric nervous system and in turn leads to intestinal symptoms and mood disorders." | 3.96 | Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome. ( Bai, Y; Cui, Z; Li, P; Li, Y; Wang, D; Wang, Y; Zhang, J; Zheng, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chojnacki, C | 1 |
| Błońska, A | 1 |
| Konrad, P | 1 |
| Chojnacki, M | 1 |
| Podogrocki, M | 1 |
| Poplawski, T | 1 |
| Li, P | 1 |
| Zheng, J | 1 |
| Bai, Y | 1 |
| Wang, D | 1 |
| Cui, Z | 1 |
| Li, Y | 1 |
| Zhang, J | 1 |
| Wang, Y | 1 |
| Keszthelyi, D | 1 |
| Troost, FJ | 1 |
| Jonkers, DM | 1 |
| Kruimel, JW | 1 |
| Leue, C | 1 |
| Masclee, AA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Serotonergic Modulation on Intestinal Permeability and Visceral Hypersensitivity in Healthy Individuals and IBS Patients[NCT00731003] | 60 participants (Actual) | Interventional | 2009-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for kynurenic acid and Colitis, Mucous
| Article | Year |
|---|---|
Changes in Tryptophan Metabolism on Serotonin and Kynurenine Pathways in Patients with Irritable Bowel Syndrome.
Topics: Chromatography, Liquid; Humans; Hydroxyindoleacetic Acid; Irritable Bowel Syndrome; Kynurenic Acid; | 2023 |
Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome.
Topics: Diarrhea; Female; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Kynurenic Acid; Kynurenine; M | 2020 |
Decreased levels of kynurenic acid in the intestinal mucosa of IBS patients: relation to serotonin and psychological state.
Topics: Adolescent; Adult; Duodenum; Female; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Kynurenic | 2013 |