Page last updated: 2024-10-30

kynurenic acid and Chronic Kidney Diseases

kynurenic acid has been researched along with Chronic Kidney Diseases in 6 studies

Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.

Research Excerpts

ExcerptRelevanceReference
"Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation."7.83Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. ( Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA, 2016)
"Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation."3.83Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. ( Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Chen, Y1
Zelnick, LR1
Huber, MP1
Wang, K1
Bansal, N1
Hoofnagle, AN1
Paranji, RK1
Heckbert, SR1
Weiss, NS1
Go, AS1
Hsu, CY1
Feldman, HI1
Waikar, SS1
Mehta, RC1
Srivastava, A1
Seliger, SL1
Lash, JP1
Porter, AC1
Raj, DS1
Kestenbaum, BR1
Mo, Y1
Jie, X1
Wang, L1
Ji, C1
Gu, Y1
Lu, Z1
Liu, X1
Grams, ME1
Tin, A1
Rebholz, CM1
Shafi, T1
Köttgen, A1
Perrone, RD1
Sarnak, MJ1
Inker, LA1
Levey, AS1
Coresh, J1
Zhao, J1
Karu, N1
McKercher, C1
Nichols, DS1
Davies, N1
Shellie, RA1
Hilder, EF1
Jose, MD1
Schefold, JC1
Zeden, JP1
Fotopoulou, C1
von Haehling, S1
Pschowski, R1
Hasper, D1
Volk, HD1
Schuett, C1
Reinke, P1

Trials

1 trial available for kynurenic acid and Chronic Kidney Diseases

ArticleYear
Plasma kynurenic acid/tryptophan ratio: a sensitive and reliable biomarker for the assessment of renal function.
    Renal failure, 2013, Volume: 35, Issue:5

    Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Kidney Function Tes

2013

Other Studies

5 other studies available for kynurenic acid and Chronic Kidney Diseases

ArticleYear
Association Between Kidney Clearance of Secretory Solutes and Cardiovascular Events: The Chronic Renal Insufficiency Cohort (CRIC) Study.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2021, Volume: 78, Issue:2

    Topics: Aged; Albuminuria; Chromatography, Liquid; Cohort Studies; Cresols; Female; Glomerular Filtration Ra

2021
Bupi Yishen formula attenuates kidney injury in 5/6 nephrectomized rats via the tryptophan-kynurenic acid-aryl hydrocarbon receptor pathway.
    BMC complementary medicine and therapies, 2021, Aug-10, Volume: 21, Issue:1

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Drugs, Chinese Herbal; Inflammation; Kidney;

2021
Metabolomic Alterations Associated with Cause of CKD.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Nov-07, Volume: 12, Issue:11

    Topics: Adult; Citrulline; Deoxyglucose; Female; Glomerulonephritis; Guanosine; Hippurates; Homovanillic Aci

2017
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
    BMC nephrology, 2016, 11-10, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female

2016
Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:6

    Topics: 5-Hydroxytryptophan; Adult; Aged; C-Reactive Protein; Case-Control Studies; Creatinine; Female; Huma

2009