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kynurenic acid and Brain Edema

kynurenic acid has been researched along with Brain Edema in 5 studies

Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
"Acute subdural hematoma (ASDH) gives rise to a mass effect not only by itself but also through unilateral hemispheric swelling."1.29Attenuation of hemispheric swelling associated with acute subdural hematomas by excitatory amino acid antagonist in rats. ( Hirayama, T; Kano, T; Katayama, Y; Kinoshita, K; Tsubokawa, T, 1994)
"Kynurenic acid (300 mg/kg) was administered i."1.27The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection. ( Andiné, P; Ellrén, K; Hagberg, H; Kjellmer, I; Lehmann, A; Nielsen, T; Wennberg, E, 1988)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kinoshita, K1
Katayama, Y2
Kano, T1
Hirayama, T1
Tsubokawa, T2
Tanaka, H1
Kawamata, T1
Espanol, MT1
Xu, Y1
Litt, L1
Chang, LH1
James, TL1
Weinstein, PR1
Chan, PH1
Simon, RP1
Young, RS1
Stout, S1
Cheng, J1
Andiné, P1
Lehmann, A1
Ellrén, K1
Wennberg, E1
Kjellmer, I1
Nielsen, T1
Hagberg, H1

Other Studies

5 other studies available for kynurenic acid and Brain Edema

ArticleYear
Attenuation of hemispheric swelling associated with acute subdural hematomas by excitatory amino acid antagonist in rats.
    Acta neurochirurgica. Supplementum, 1994, Volume: 60

    Topics: Animals; Brain Edema; Brain Injuries; Electron Transport Complex IV; Energy Metabolism; Excitatory A

1994
Excitatory amino acid release from contused brain tissue into surrounding brain areas.
    Acta neurochirurgica. Supplementum, 1994, Volume: 60

    Topics: Animals; Brain Concussion; Brain Edema; Excitatory Amino Acids; Extracellular Space; Frontal Lobe; G

1994
Modulation of edema by dizocilpine, kynurenate, and NBQX in respiring brain slices after exposure to glutamate.
    Acta neurochirurgica. Supplementum, 1994, Volume: 60

    Topics: Animals; Brain Edema; Cerebral Cortex; Culture Techniques; Dizocilpine Maleate; Energy Metabolism; G

1994
Inhibition of excitatory neurotransmission with kynurenate reduces brain edema in neonatal anoxia.
    Neuroscience letters, 1986, Nov-21, Volume: 71, Issue:3

    Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Edema; Brain Ischemia; Glutamates; Glutamic Acid; Hy

1986
The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection.
    Neuroscience letters, 1988, Jul-19, Volume: 90, Issue:1-2

    Topics: Animals; Brain; Brain Edema; Cerebrovascular Disorders; Female; Hypoxia; Ischemic Attack, Transient;

1988