kynurenic acid has been researched along with Bradycardia in 6 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, we investigated the effects of pretreatment with NG-nitro-L-arginine methyl ester (L-NAME) (nitric oxide synthase inhibitor) injected intravenously (IV) on the hypotension, bradycardia, and vasodilation produced by moxonidine (alpha2-adrenergic/imidazoline receptor agonist) injected into the fourth brain ventricle (4th V) in rats submitted to acute hypertension that results from baroreflex blockade by bilateral injections of kynurenic acid (kyn, glutamatergic receptor antagonist) into the nucleus of the solitary tract (NTS) or in normotensive rats." | 3.73 | Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide. ( Colombari, E; Menani, JV; Moreira, TS; Sato, MA; Takakura, AC, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, Y | 1 |
| Wu, YS | 1 |
| Chen, DS | 1 |
| Wang, MM | 1 |
| Wang, WZ | 1 |
| Yuan, WJ | 1 |
| Cardoso, LM | 1 |
| Colombari, DS | 1 |
| Menani, JV | 2 |
| Toney, GM | 1 |
| Chianca, DA | 1 |
| Colombari, E | 2 |
| Moreira, TS | 1 |
| Takakura, AC | 1 |
| Sato, MA | 1 |
| Mauad, H | 1 |
| Machado, BH | 1 |
| Takemoto, Y | 1 |
| Yamanashi, K | 1 |
| Miyamae, T | 1 |
| Sasaki, Y | 1 |
| Maeda, M | 1 |
| Hirano, H | 1 |
| Misu, Y | 1 |
| Goshima, Y | 1 |
6 other studies available for kynurenic acid and Bradycardia
| Article | Year |
|---|---|
Microinjection of salusin-beta into the nucleus tractus solitarii inhibits cardiovascular function by suppressing presympathetic neurons in rostral ventrolateral medulla in rats.
Topics: Animals; Baroreflex; Bradycardia; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonist | 2015 |
Cardiovascular responses to hydrogen peroxide into the nucleus tractus solitarius.
Topics: Amitrole; Anesthesia; Animals; Ascorbic Acid; Blood Pressure; Bradycardia; Cardiovascular System; Ch | 2009 |
Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide.
Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradycardia; Drug Interactions; Endoth | 2006 |
Pressor response to unilateral carotid chemoreceptor activation is not affected by ipsilateral antagonism of excitatory amino acid receptors in the rostral ventrolateral medulla of awake rats.
Topics: Animals; Blood Pressure; Bradycardia; Carotid Arteries; Carotid Body; Chemoreceptor Cells; Excitator | 2001 |
Depressor and bradycardic actions of L-proline injected into the nucleus tractus solitarii of anesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Bradycardia; Dose-Response Relationship, Drug; Excitatory Amino | 2001 |
Involvement of nitric oxide production via kynurenic acid-sensitive glutamate receptors in DOPA-induced depressor responses in the nucleus tractus solitarii of anesthetized rats.
Topics: Anesthetics, Intravenous; Animals; Blood Pressure; Bradycardia; Dihydroxyphenylalanine; Kynurenic Ac | 2002 |