kynurenic acid has been researched along with Blood Poisoning in 4 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-six patients with severe sepsis/septic shock and sepsis-associated immunosuppression (assessed using monocytic human leukocyte antigen-DR (mHLA-DR) expression) were assessed in a controlled trial of GM-CSF or placebo treatment for 8 days." | 6.75 | Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock. ( Fotopoulou, C; Fusch, G; Hammoud, B; Hasper, D; Meisel, C; Pschowski, R; Reinke, P; Schefold, JC; Schütt, C; Volk, HD; Von Haehling, S; Zeden, JP, 2010) |
| "Sepsis was characterized by significantly elevated ROFA scores, while the increased BBB permeability and plasma S100B levels demonstrated brain damage." | 5.62 | Kynurenic Acid and Its Synthetic Derivatives Protect Against Sepsis-Associated Neutrophil Activation and Brain Mitochondrial Dysfunction in Rats. ( Boros, M; Czakó, BL; Dookhun, D; Fülöp, F; Gál, KG; Glenz, RJ; Gulácsi, L; Juhász, L; Kaszaki, J; Lőrinczi, B; Nászai, A; Poles, MZ; Rutai, A; Szabó, A; Szatmári, I; Tallósy, SP; Vécsei, L, 2021) |
| "Thirty-six patients with severe sepsis/septic shock and sepsis-associated immunosuppression (assessed using monocytic human leukocyte antigen-DR (mHLA-DR) expression) were assessed in a controlled trial of GM-CSF or placebo treatment for 8 days." | 2.75 | Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock. ( Fotopoulou, C; Fusch, G; Hammoud, B; Hasper, D; Meisel, C; Pschowski, R; Reinke, P; Schefold, JC; Schütt, C; Volk, HD; Von Haehling, S; Zeden, JP, 2010) |
| "Kynurenic acid is a common differential metabolite that could be used as a candidate for both diagnosis and prognosis for septic patients with cardiac dysfunction." | 1.91 | Untargeted metabolomic profiling of sepsis-induced cardiac dysfunction. ( Cao, Y; Fang, C; Han, X; Huang, J; Jing, Y; Liu, Z; Ma, W; Pei, Y; Xiao, W, 2023) |
| "Sepsis was characterized by significantly elevated ROFA scores, while the increased BBB permeability and plasma S100B levels demonstrated brain damage." | 1.62 | Kynurenic Acid and Its Synthetic Derivatives Protect Against Sepsis-Associated Neutrophil Activation and Brain Mitochondrial Dysfunction in Rats. ( Boros, M; Czakó, BL; Dookhun, D; Fülöp, F; Gál, KG; Glenz, RJ; Gulácsi, L; Juhász, L; Kaszaki, J; Lőrinczi, B; Nászai, A; Poles, MZ; Rutai, A; Szabó, A; Szatmári, I; Tallósy, SP; Vécsei, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poles, MZ | 1 |
| Nászai, A | 1 |
| Gulácsi, L | 1 |
| Czakó, BL | 1 |
| Gál, KG | 1 |
| Glenz, RJ | 1 |
| Dookhun, D | 1 |
| Rutai, A | 1 |
| Tallósy, SP | 1 |
| Szabó, A | 1 |
| Lőrinczi, B | 1 |
| Szatmári, I | 1 |
| Fülöp, F | 1 |
| Vécsei, L | 1 |
| Boros, M | 1 |
| Juhász, L | 1 |
| Kaszaki, J | 1 |
| Cao, Y | 1 |
| Liu, Z | 1 |
| Ma, W | 1 |
| Fang, C | 1 |
| Pei, Y | 1 |
| Jing, Y | 1 |
| Huang, J | 1 |
| Han, X | 1 |
| Xiao, W | 1 |
| Schefold, JC | 1 |
| Zeden, JP | 1 |
| Pschowski, R | 1 |
| Hammoud, B | 1 |
| Fotopoulou, C | 1 |
| Hasper, D | 1 |
| Fusch, G | 1 |
| Von Haehling, S | 1 |
| Volk, HD | 1 |
| Meisel, C | 1 |
| Schütt, C | 1 |
| Reinke, P | 1 |
| Heyes, MP | 1 |
| Lackner, A | 1 |
1 trial available for kynurenic acid and Blood Poisoning
| Article | Year |
|---|---|
Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock.
Topics: Aged; Calcitonin; Calcitonin Gene-Related Peptide; Granulocyte-Macrophage Colony-Stimulating Factor; | 2010 |
3 other studies available for kynurenic acid and Blood Poisoning
| Article | Year |
|---|---|
Kynurenic Acid and Its Synthetic Derivatives Protect Against Sepsis-Associated Neutrophil Activation and Brain Mitochondrial Dysfunction in Rats.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Kynurenic Acid; Male; Mitochondria; Neuroprote | 2021 |
Untargeted metabolomic profiling of sepsis-induced cardiac dysfunction.
Topics: Chromatography, Liquid; Discriminant Analysis; Humans; Kynurenic Acid; Metabolomics; Sepsis | 2023 |
Increased cerebrospinal fluid quinolinic acid, kynurenic acid, and L-kynurenine in acute septicemia.
Topics: Acute Disease; Animals; Female; Kynurenic Acid; Kynurenine; Macaca mulatta; Male; Pyridines; Quinoli | 1990 |