kynurenic acid has been researched along with Apoplexy in 8 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The kynurenine pathway is the main metabolic pathway of tryptophan degradation and has been associated with stroke and impaired cognitive functioning, but studies on its role in post-stroke cognitive impairment (PSCI) are scarce." | 8.31 | The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study. ( Bakker, L; Choe, K; J P M Eussen, S; Kenis, G; Köhler, S; Ramakers, IHGB; Rutten, BPF; Staals, J; Ueland, PM; Ulvik, A; van den Hove, DLA; van Oostenbrugge, RJ; Verhey, FRJ, 2023) |
| "046), and neopterin was associated with the combined endpoint (recurrent ischemic stroke or death) (HR 1." | 8.02 | Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke. ( Alme, KN; Askim, T; Assmus, J; Knapskog, AB; Mollnes, TE; Naik, M; Næss, H; Saltvedt, I; Ueland, PM; Ulvik, A, 2021) |
| "To investigate if there is a correlation between serum kynurenines levels with poststroke anxiety and depression symptoms and disability scales." | 7.96 | Serum Kynurenines Correlate With Depressive Symptoms and Disability in Poststroke Patients: A Cross-sectional Study. ( Barajas-Martínez, K; Carrillo-Mora, P; Estrada-Cortés, B; Franyutti-Prado, K; Gamboa-Coria, G; Martínez-Cortéz, JA; Pérez-De la Cruz, V; Quinzaños-Fresnedo, J; Ramírez-Ortega, D; Ramos-Chávez, LA; Rangel-Caballero, F; Rodríguez-Barragán, M; Sánchez-Chapul, L; Sánchez-Vázquez, I; Toussaint-González, P, 2020) |
| "The kynurenine pathway is a complex enzymatic cascade of tryptophan catabolism, generating various neuroactive metabolites." | 6.58 | Ischemic Stroke and Kynurenines: Medicinal Chemistry Aspects. ( Fülöp, F; Hertelendy, P; Toldi, J; Vécsei, L, 2018) |
| "The kynurenine pathway is the main metabolic pathway of tryptophan degradation and has been associated with stroke and impaired cognitive functioning, but studies on its role in post-stroke cognitive impairment (PSCI) are scarce." | 4.31 | The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study. ( Bakker, L; Choe, K; J P M Eussen, S; Kenis, G; Köhler, S; Ramakers, IHGB; Rutten, BPF; Staals, J; Ueland, PM; Ulvik, A; van den Hove, DLA; van Oostenbrugge, RJ; Verhey, FRJ, 2023) |
| "046), and neopterin was associated with the combined endpoint (recurrent ischemic stroke or death) (HR 1." | 4.02 | Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke. ( Alme, KN; Askim, T; Assmus, J; Knapskog, AB; Mollnes, TE; Naik, M; Næss, H; Saltvedt, I; Ueland, PM; Ulvik, A, 2021) |
| "To investigate if there is a correlation between serum kynurenines levels with poststroke anxiety and depression symptoms and disability scales." | 3.96 | Serum Kynurenines Correlate With Depressive Symptoms and Disability in Poststroke Patients: A Cross-sectional Study. ( Barajas-Martínez, K; Carrillo-Mora, P; Estrada-Cortés, B; Franyutti-Prado, K; Gamboa-Coria, G; Martínez-Cortéz, JA; Pérez-De la Cruz, V; Quinzaños-Fresnedo, J; Ramírez-Ortega, D; Ramos-Chávez, LA; Rangel-Caballero, F; Rodríguez-Barragán, M; Sánchez-Chapul, L; Sánchez-Vázquez, I; Toussaint-González, P, 2020) |
| "The kynurenine pathway is a complex enzymatic cascade of tryptophan catabolism, generating various neuroactive metabolites." | 2.58 | Ischemic Stroke and Kynurenines: Medicinal Chemistry Aspects. ( Fülöp, F; Hertelendy, P; Toldi, J; Vécsei, L, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 5 (62.50) | 2.80 |
| Authors | Studies |
|---|---|
| Annus, Á | 1 |
| Tömösi, F | 1 |
| Rárosi, F | 1 |
| Fehér, E | 1 |
| Janáky, T | 1 |
| Kecskeméti, G | 1 |
| Toldi, J | 2 |
| Klivényi, P | 1 |
| Sztriha, L | 1 |
| Vécsei, L | 2 |
| Alme, KN | 1 |
| Ulvik, A | 2 |
| Askim, T | 1 |
| Assmus, J | 1 |
| Mollnes, TE | 1 |
| Naik, M | 1 |
| Næss, H | 1 |
| Saltvedt, I | 1 |
| Ueland, PM | 2 |
| Knapskog, AB | 1 |
| Bakker, L | 1 |
| Ramakers, IHGB | 1 |
| J P M Eussen, S | 1 |
| Choe, K | 1 |
| van den Hove, DLA | 1 |
| Kenis, G | 1 |
| Rutten, BPF | 1 |
| van Oostenbrugge, RJ | 1 |
| Staals, J | 1 |
| Verhey, FRJ | 1 |
| Köhler, S | 1 |
| Carrillo-Mora, P | 1 |
| Pérez-De la Cruz, V | 1 |
| Estrada-Cortés, B | 1 |
| Toussaint-González, P | 1 |
| Martínez-Cortéz, JA | 1 |
| Rodríguez-Barragán, M | 1 |
| Quinzaños-Fresnedo, J | 1 |
| Rangel-Caballero, F | 1 |
| Gamboa-Coria, G | 1 |
| Sánchez-Vázquez, I | 1 |
| Barajas-Martínez, K | 1 |
| Franyutti-Prado, K | 1 |
| Sánchez-Chapul, L | 1 |
| Ramírez-Ortega, D | 1 |
| Ramos-Chávez, LA | 1 |
| Chen, Y | 1 |
| Zelnick, LR | 1 |
| Huber, MP | 1 |
| Wang, K | 1 |
| Bansal, N | 1 |
| Hoofnagle, AN | 1 |
| Paranji, RK | 1 |
| Heckbert, SR | 1 |
| Weiss, NS | 1 |
| Go, AS | 1 |
| Hsu, CY | 1 |
| Feldman, HI | 1 |
| Waikar, SS | 1 |
| Mehta, RC | 1 |
| Srivastava, A | 1 |
| Seliger, SL | 1 |
| Lash, JP | 1 |
| Porter, AC | 1 |
| Raj, DS | 1 |
| Kestenbaum, BR | 1 |
| Hertelendy, P | 1 |
| Fülöp, F | 1 |
| Mangas, A | 1 |
| Yajeya, J | 1 |
| González, N | 1 |
| Ruiz, I | 1 |
| Duleu, S | 1 |
| Geffard, M | 1 |
| Coveñas, R | 1 |
| Nowicka-Stążka, P | 1 |
| Stążka, K | 1 |
| Dąbrowski, W | 1 |
| Turski, W | 1 |
| Majdan, M | 1 |
| Parada-Turska, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Norwegian COgnitive Impairment After STroke (NorCOAST) Study[NCT02650531] | 816 participants (Actual) | Observational | 2015-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for kynurenic acid and Apoplexy
| Article | Year |
|---|---|
Ischemic Stroke and Kynurenines: Medicinal Chemistry Aspects.
Topics: Excitatory Amino Acid Antagonists; Humans; Kynurenic Acid; Kynurenine; Quinolinic Acids; Receptors, | 2018 |
[Kynurenic acid--a new tool in the treatment of hiperhomocysteinemia and its consequences?].
Topics: Atherosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; | 2012 |
6 other studies available for kynurenic acid and Apoplexy
| Article | Year |
|---|---|
Kynurenic acid and kynurenine aminotransferase are potential biomarkers of early neurological improvement after thrombolytic therapy: A pilot study.
Topics: Biomarkers; Brain Ischemia; Humans; Kynurenic Acid; Pilot Projects; Stroke; Thrombolytic Therapy; Tr | 2021 |
Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke.
Topics: Aged; Biomarkers; Brain Ischemia; Cohort Studies; Female; Humans; Inflammation; Ischemic Stroke; Kyn | 2021 |
The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study.
Topics: Biomarkers; Cognition; Female; Humans; Kynurenic Acid; Kynurenine; Male; Prospective Studies; Stroke | 2023 |
Serum Kynurenines Correlate With Depressive Symptoms and Disability in Poststroke Patients: A Cross-sectional Study.
Topics: Adult; Aged; Case-Control Studies; Cross-Sectional Studies; Depression; Female; Functional Status; H | 2020 |
Association Between Kidney Clearance of Secretory Solutes and Cardiovascular Events: The Chronic Renal Insufficiency Cohort (CRIC) Study.
Topics: Aged; Albuminuria; Chromatography, Liquid; Cohort Studies; Cresols; Female; Glomerular Filtration Ra | 2021 |
Overexpression of kynurenic acid in stroke: An endogenous neuroprotector?
Topics: Animals; Cerebral Cortex; Corpus Striatum; Kynurenic Acid; Male; Neuroprotection; Rats; Rats, Wistar | 2017 |