kynurenic acid has been researched along with Apnea in 5 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Apnea: A transient absence of spontaneous respiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 18: 6048-6056, 1998], who postulated a role for the ITR in modulating reflex apnea." | 8.82 | Modulation of reflex and sleep related apnea by pedunculopontine tegmental and intertrigeminal neurons. ( Carley, DW; Pavlovic, S; Radulovacki, M; Saponjic, J, 2004) |
| "In 35 adult cats anesthetized with intraperitoneal chloralose and urethane, the ventrolateral medulla was explored by microinjection of kainic acid (KA, 24 mM, 200 nl) with metal electrode-tubing or glass micropipette to determine regions which elicit persistent apnea." | 7.70 | A single minute lesion around the ventral respiratory group in medulla produces fatal apnea in cats. ( Chai, CY; Chang, YC; Hsieh, JH; Hwang, JC; Su, CK; Yen, CT, 1998) |
| " 18: 6048-6056, 1998], who postulated a role for the ITR in modulating reflex apnea." | 4.82 | Modulation of reflex and sleep related apnea by pedunculopontine tegmental and intertrigeminal neurons. ( Carley, DW; Pavlovic, S; Radulovacki, M; Saponjic, J, 2004) |
| "Respiratory disturbance, including apnea, can be induced by microinjection of glutamate into the intertrigeminal region (ITR) of the lateral pons, a region that is anatomically coupled to both the dorsal and ventral respiratory groups of the medulla." | 3.74 | Effects of intertrigeminal region NMDA and non-NMDA receptors on respiratory responses in rats. ( Carley, DW; Radulovacki, M; Saponjic, J; Stoiljkovic, M, 2007) |
| " Microinjection of the bicuculline produced apnea, whereas microinjection of CGP-35348 produced a decrease in Ti and an increase in expiratory duration." | 3.71 | GABA-mediated neurotransmission in the ventrolateral NTS plays a role in respiratory regulation in the rat. ( Ferreira, M; Gillis, RA; Hernandez, YM; Sahibzada, N; Wasserman, AM, 2002) |
| "In 35 adult cats anesthetized with intraperitoneal chloralose and urethane, the ventrolateral medulla was explored by microinjection of kainic acid (KA, 24 mM, 200 nl) with metal electrode-tubing or glass micropipette to determine regions which elicit persistent apnea." | 3.70 | A single minute lesion around the ventral respiratory group in medulla produces fatal apnea in cats. ( Chai, CY; Chang, YC; Hsieh, JH; Hwang, JC; Su, CK; Yen, CT, 1998) |
| "5 nmol of L-glutamate into the caudal subretrofacial area produced apnea in eight of eight animals tested, and the duration of apnea was 27 +/- 2 s." | 3.69 | Respiratory effects produced by microinjection of L-glutamate and an uptake inhibitor of L-glutamate into the caudal subretrofacial area of the medulla. ( DaSilva, AM; Gillis, RA; McManigle, JE; Panico, WH, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wasserman, AM | 1 |
| Ferreira, M | 1 |
| Sahibzada, N | 1 |
| Hernandez, YM | 1 |
| Gillis, RA | 2 |
| Radulovacki, M | 2 |
| Pavlovic, S | 1 |
| Saponjic, J | 2 |
| Carley, DW | 2 |
| Stoiljkovic, M | 1 |
| McManigle, JE | 1 |
| Panico, WH | 1 |
| DaSilva, AM | 1 |
| Hsieh, JH | 1 |
| Chang, YC | 1 |
| Su, CK | 1 |
| Hwang, JC | 1 |
| Yen, CT | 1 |
| Chai, CY | 1 |
1 review available for kynurenic acid and Apnea
| Article | Year |
|---|---|
Modulation of reflex and sleep related apnea by pedunculopontine tegmental and intertrigeminal neurons.
Topics: Animals; Apnea; Brain Mapping; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Ac | 2004 |
4 other studies available for kynurenic acid and Apnea
| Article | Year |
|---|---|
GABA-mediated neurotransmission in the ventrolateral NTS plays a role in respiratory regulation in the rat.
Topics: Animals; Apnea; Baclofen; Bicuculline; Cardiovascular System; Fluorescent Antibody Technique; GABA A | 2002 |
Effects of intertrigeminal region NMDA and non-NMDA receptors on respiratory responses in rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Apnea; Excitatory Amino Acid Antagonists | 2007 |
Respiratory effects produced by microinjection of L-glutamate and an uptake inhibitor of L-glutamate into the caudal subretrofacial area of the medulla.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Apnea; Blood Pressure; Cats; Cycloleucine; Dicarboxyl | 1995 |
A single minute lesion around the ventral respiratory group in medulla produces fatal apnea in cats.
Topics: Animals; Apnea; Autonomic Nervous System; Cats; Denervation; Electric Stimulation; Excitatory Amino | 1998 |