kynurenic acid has been researched along with Alloxan Diabetes in 10 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current study analysed kynurenine aminotransferase I (KAT I) activity and kynurenic acid (KYNA) concentrations in human senile cataractous lenses and in experimentally induced cataracts in diabetic rats treated with streptozotocin (STZ)." | 7.74 | Elevated concentrations of kynurenic acid, a tryptophan derivative, in dense nuclear cataracts. ( Grieb, P; Junemann, A; Rejdak, R; Turski, WA; Zagórski, Z; Zarnowski, T; Zielinska-Rzecka, E; Zrenner, E, 2007) |
| "Diabetic cataract was induced in male Wistar-NIN rats by IP injection of STZ (34 mg/kg body wt)." | 5.35 | Elevated Expression of indoleamine 2,3-dioxygenase (IDO) and accumulation of kynurenic acid in the pathogenesis of STZ-induced diabetic cataract in Wistar rats. ( Kanth, VR; Lavanya, K; Raju, TN; Srinivas, J, 2009) |
| " The current study analysed kynurenine aminotransferase I (KAT I) activity and kynurenic acid (KYNA) concentrations in human senile cataractous lenses and in experimentally induced cataracts in diabetic rats treated with streptozotocin (STZ)." | 3.74 | Elevated concentrations of kynurenic acid, a tryptophan derivative, in dense nuclear cataracts. ( Grieb, P; Junemann, A; Rejdak, R; Turski, WA; Zagórski, Z; Zarnowski, T; Zielinska-Rzecka, E; Zrenner, E, 2007) |
| "Glaucoma is an optic neuropathy and involves the progressive degeneration of retinal ganglion cells (RGCs), which leads to blindness in patients." | 1.56 | Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice. ( Houck, JA; Johnson, GC; MacLean, PS; Nagaraj, RH; Nahomi, RB; Nam, MH; Pantcheva, MB; Rakete, S; Rankenberg, J; Stankowska, DL, 2020) |
| "Diabetic cataract was induced in male Wistar-NIN rats by IP injection of STZ (34 mg/kg body wt)." | 1.35 | Elevated Expression of indoleamine 2,3-dioxygenase (IDO) and accumulation of kynurenic acid in the pathogenesis of STZ-induced diabetic cataract in Wistar rats. ( Kanth, VR; Lavanya, K; Raju, TN; Srinivas, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chmiel-Perzyńska, I | 2 |
| Perzyński, A | 2 |
| Olajossy, B | 1 |
| Gil-Kulik, P | 1 |
| Kocki, J | 1 |
| Urbańska, EM | 2 |
| Nahomi, RB | 1 |
| Nam, MH | 1 |
| Rankenberg, J | 1 |
| Rakete, S | 1 |
| Houck, JA | 1 |
| Johnson, GC | 1 |
| Stankowska, DL | 1 |
| Pantcheva, MB | 1 |
| MacLean, PS | 1 |
| Nagaraj, RH | 1 |
| Boychuk, CR | 1 |
| Smith, BN | 1 |
| Yue, JT | 1 |
| Abraham, MA | 1 |
| Bauer, PV | 1 |
| LaPierre, MP | 1 |
| Wang, P | 1 |
| Duca, FA | 1 |
| Filippi, BM | 1 |
| Chan, O | 1 |
| Lam, TK | 1 |
| Kanth, VR | 1 |
| Lavanya, K | 1 |
| Srinivas, J | 1 |
| Raju, TN | 1 |
| Patterson, AD | 1 |
| Bonzo, JA | 1 |
| Li, F | 1 |
| Krausz, KW | 1 |
| Eichler, GS | 1 |
| Aslam, S | 1 |
| Tigno, X | 1 |
| Weinstein, JN | 1 |
| Hansen, BC | 1 |
| Idle, JR | 1 |
| Gonzalez, FJ | 1 |
| Zarnowski, T | 1 |
| Rejdak, R | 1 |
| Zielinska-Rzecka, E | 1 |
| Zrenner, E | 1 |
| Grieb, P | 1 |
| Zagórski, Z | 1 |
| Junemann, A | 1 |
| Turski, WA | 1 |
| Numa, S | 1 |
| Hashimoto, T | 1 |
| Nakanishi, S | 1 |
| Okazaki, T | 1 |
| Sanders, RB | 1 |
| Abulaban, FS | 1 |
10 other studies available for kynurenic acid and Alloxan Diabetes
| Article | Year |
|---|---|
Losartan Reverses Hippocampal Increase of Kynurenic Acid in Type 1 Diabetic Rats: A Novel Procognitive Aspect of Sartan Action.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus | 2019 |
Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Excitatory Amino Acid Antagonists; | 2020 |
Experimental diabetes mellitus type 1 increases hippocampal content of kynurenic acid in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Cognition; Corpus Striatum; Diabetes Mellitus, Experi | 2014 |
Glutamatergic drive facilitates synaptic inhibition of dorsal vagal motor neurons after experimentally induced diabetes in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid | 2016 |
Inhibition of glycine transporter-1 in the dorsal vagal complex improves metabolic homeostasis in diabetes and obesity.
Topics: Animals; Brain; Diabetes Mellitus, Experimental; Diet, High-Fat; Energy Metabolism; Gene Expression | 2016 |
Elevated Expression of indoleamine 2,3-dioxygenase (IDO) and accumulation of kynurenic acid in the pathogenesis of STZ-induced diabetic cataract in Wistar rats.
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Down-Regulation; Glutathione; Indoleamine-Pyrrol | 2009 |
Metabolomics reveals attenuation of the SLC6A20 kidney transporter in nonhuman primate and mouse models of type 2 diabetes mellitus.
Topics: Amino Acid Transport Systems, Neutral; Animals; Betaine; Citric Acid; Diabetes Mellitus, Experimenta | 2011 |
Elevated concentrations of kynurenic acid, a tryptophan derivative, in dense nuclear cataracts.
Topics: Animals; Cataract; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Humans; Ky | 2007 |
Regulatory mechanisms for liver acetyl coenzyme A carboxylase.
Topics: Acetyl-CoA Carboxylase; Animals; Bicarbonates; Diabetes Mellitus, Experimental; Fasting; Kinetics; K | 1972 |
L-Amino acid inhibition of epinephrine-induced hyperglycemia.
Topics: Amino Acids; Animals; Caseins; Cattle; Depression, Chemical; Diabetes Mellitus, Experimental; Epinep | 1971 |