kynurenic acid has been researched along with Alcoholism in 10 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "For this purpose, male and female abstinent AUD patients (N = 130) and healthy controls (N = 80) were clinically evaluated for substance use and mental disorders, and blood samples were collected to determine plasma concentrations of TRP, 5-HT, KYN and kynurenic acid (KA) using high performance liquid chromatography." | 3.96 | Plasma tryptophan and kynurenine pathway metabolites in abstinent patients with alcohol use disorder and high prevalence of psychiatric comorbidity. ( Araos, P; Colado, MI; Flores-López, M; García-Marchena, N; O'Shea, E; Pavón, FJ; Requena-Ocaña, N; Rodríguez de Fonseca, F; Rubio, G; Serrano, A; Suárez, J; Vidal, R, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 4 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leclercq, S | 1 |
| Schwarz, M | 1 |
| Delzenne, NM | 1 |
| Stärkel, P | 1 |
| de Timary, P | 1 |
| Mechtcheriakov, S | 1 |
| Gleissenthall, GV | 1 |
| Geisler, S | 1 |
| Arnhard, K | 1 |
| Oberacher, H | 1 |
| Schurr, T | 1 |
| Kemmler, G | 1 |
| Unterberger, C | 1 |
| Fuchs, D | 1 |
| Wang, Z | 1 |
| Huang, S | 1 |
| Li, L | 1 |
| Wen, Y | 1 |
| Shang, D | 1 |
| Vidal, R | 1 |
| García-Marchena, N | 1 |
| O'Shea, E | 1 |
| Requena-Ocaña, N | 1 |
| Flores-López, M | 1 |
| Araos, P | 1 |
| Serrano, A | 1 |
| Suárez, J | 1 |
| Rubio, G | 1 |
| Rodríguez de Fonseca, F | 1 |
| Colado, MI | 1 |
| Pavón, FJ | 1 |
| Badawy, AA | 1 |
| Vengeliene, V | 1 |
| Hoffman, PL | 1 |
| Iorio, KR | 1 |
| Snell, LD | 1 |
| Tabakoff, B | 1 |
| Pierce, HI | 1 |
| McGuffin, RG | 1 |
| Hillman, RS | 1 |
| Morgan, PF | 1 |
| Payne, IR | 1 |
| Lu, GH | 1 |
| Meyer, K | 1 |
1 review available for kynurenic acid and Alcoholism
| Article | Year |
|---|---|
Kynurenine metabolite changes in individuals with alcohol use disorder: A systematic review and meta-analysis.
Topics: Alcoholism; Humans; Kynurenic Acid; Kynurenine; Tryptophan | 2023 |
9 other studies available for kynurenic acid and Alcoholism
| Article | Year |
|---|---|
Alterations of kynurenine pathway in alcohol use disorder and abstinence: a link with gut microbiota, peripheral inflammation and psychological symptoms.
Topics: Alcoholism; Gastrointestinal Microbiome; Humans; Inflammation; Kynurenic Acid; Kynurenine; Quinolini | 2021 |
Tryptophan-kynurenine metabolism during acute alcohol withdrawal in patients with alcohol use disorder: The role of immune activation.
Topics: Alcohol Drinking; Alcoholism; Biomarkers; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Ac | 2022 |
Plasma tryptophan and kynurenine pathway metabolites in abstinent patients with alcohol use disorder and high prevalence of psychiatric comorbidity.
Topics: Adolescent; Adult; Aged; Aging; Alcohol Abstinence; Alcoholism; Body Mass Index; Cross-Sectional Stu | 2020 |
Kynurenic acid and alcohol and cocaine dependence: novel effects and multiple mechanisms?
Topics: Alcoholism; Cocaine; Cocaine-Related Disorders; Ethanol; Humans; Kynurenic Acid | 2017 |
Reply to: kynurenic acid and alcohol and cocaine dependence: novel effects and multiple mechanisms?
Topics: Alcoholism; Cocaine; Cocaine-Related Disorders; Ethanol; Humans; Kynurenic Acid | 2017 |
Attenuation of glutamate-induced neurotoxicity in chronically ethanol-exposed cerebellar granule cells by NMDA receptor antagonists and ganglioside GM1.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Diz | 1995 |
Clinical studies in alcoholic sideroblastosis.
Topics: Adult; Aged; Alcoholism; Anemia, Sideroblastic; Chronic Disease; Diet; Erythropoiesis; Ethanol; Foli | 1976 |
Is quinolinic acid an endogenous excitotoxin in alcohol withdrawal?
Topics: Alcoholism; Animals; Brain; Humans; Kynurenic Acid; Models, Neurological; Quinolinic Acid; Quinolini | 1991 |
Relationship of dietary tryptophan and niacin to tryptophan metabolism in alcoholics and nonalcoholics.
Topics: Acetates; Alcoholism; Aminohippuric Acids; Diet; Dietary Proteins; Female; Humans; Hydroxyindoleacet | 1974 |