kynurenic acid has been researched along with Acute Brain Injuries in 11 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Excerpt | Relevance | Reference |
---|---|---|
"Clinical studies indicate that phenytoin prevents acute post-traumatic seizures but not subsequent post-traumatic epilepsy." | 3.78 | Interictal spikes, seizures and ictal cell death are not necessary for post-traumatic epileptogenesis in vitro. ( Berdichevsky, Y; Dzhala, V; Mail, M; Staley, KJ, 2012) |
"Acute subdural hematoma (ASDH) gives rise to a mass effect not only by itself but also through unilateral hemispheric swelling." | 1.29 | Attenuation of hemispheric swelling associated with acute subdural hematomas by excitatory amino acid antagonist in rats. ( Hirayama, T; Kano, T; Katayama, Y; Kinoshita, K; Tsubokawa, T, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 9 (81.82) | 18.2507 |
2000's | 1 (9.09) | 29.6817 |
2010's | 1 (9.09) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Berdichevsky, Y | 1 |
Dzhala, V | 1 |
Mail, M | 1 |
Staley, KJ | 1 |
Suma, T | 1 |
Koshinaga, M | 1 |
Fukushima, M | 1 |
Kano, T | 2 |
Katayama, Y | 4 |
Hicks, RR | 2 |
Smith, DH | 3 |
McIntosh, TK | 2 |
Gennarelli, TA | 1 |
McIntosh, T | 1 |
Kinoshita, K | 1 |
Hirayama, T | 1 |
Tsubokawa, T | 1 |
Okiyama, K | 1 |
Thomas, MJ | 1 |
Walker, DW | 1 |
Curtis, B | 1 |
Lacey, B | 1 |
Nitsos, I | 1 |
Dhillon, HS | 1 |
Prasad, RM | 1 |
D'Ambrosio, R | 1 |
Maris, DO | 1 |
Grady, MS | 1 |
Winn, HR | 1 |
Janigro, D | 1 |
Becker, DP | 2 |
Tamura, T | 1 |
Ikezaki, K | 1 |
Hovda, DA | 1 |
Yoshino, A | 1 |
Kawamata, T | 1 |
Fineman, I | 1 |
11 other studies available for kynurenic acid and Acute Brain Injuries
Article | Year |
---|---|
Interictal spikes, seizures and ictal cell death are not necessary for post-traumatic epileptogenesis in vitro.
Topics: Action Potentials; Animals; Anticonvulsants; Brain Injuries; Cell Death; Epilepsy; Excitatory Amino | 2012 |
Effects of in situ administration of excitatory amino acid antagonists on rapid microglial and astroglial reactions in rat hippocampus following traumatic brain injury.
Topics: Animals; Astrocytes; Brain Injuries; CD11b Antigen; Disease Models, Animal; Excitatory Amino Acid An | 2008 |
Temporal response and effects of excitatory amino acid antagonism on microtubule-associated protein 2 immunoreactivity following experimental brain injury in rats.
Topics: Animals; Brain Injuries; Cell Survival; Cerebral Cortex; Cytoskeleton; Excitatory Amino Acid Antagon | 1995 |
Kynurenate is neuroprotective following experimental brain injury in the rat.
Topics: Animals; Body Temperature; Brain Injuries; Cell Survival; Hippocampus; Kynurenic Acid; Male; Neurons | 1994 |
Attenuation of hemispheric swelling associated with acute subdural hematomas by excitatory amino acid antagonist in rats.
Topics: Animals; Brain Edema; Brain Injuries; Electron Transport Complex IV; Energy Metabolism; Excitatory A | 1994 |
Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury.
Topics: Animals; Brain; Brain Injuries; Carboxylic Acids; Cations; Indoles; Kynurenic Acid; Male; Memory Dis | 1993 |
Kynurenic acid in brain and cerebrospinal fluid of fetal, newborn, and adult sheep and effects of placental embolization.
Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Embolism; Female; Fetal Hypoxia; Fetus; Kynurenic | 1999 |
Kynurenate attenuates the accumulation of diacylglycerol and free fatty acids after experimental brain injury in the rat.
Topics: Analysis of Variance; Animals; Brain Injuries; Diglycerides; Drug Evaluation, Preclinical; Excitator | 1999 |
Impaired K(+) homeostasis and altered electrophysiological properties of post-traumatic hippocampal glia.
Topics: Animals; Astrocytes; Brain Injuries; Electric Stimulation; Glial Fibrillary Acidic Protein; Hippocam | 1999 |
Early cellular swelling in experimental traumatic brain injury: a phenomenon mediated by excitatory amino acids.
Topics: Amino Acids; Animals; Body Water; Brain Injuries; Female; Ions; Kynurenic Acid; Neurons; Potassium; | 1990 |
The increase in local cerebral glucose utilization following fluid percussion brain injury is prevented with kynurenic acid and is associated with an increase in calcium.
Topics: Animals; Brain; Brain Injuries; Calcium; Dialysis; Glucose; Kynurenic Acid; Male; Rats; Rats, Inbred | 1990 |