kynurenic acid has been researched along with Acquired-Immune Deficiency Syndrome Dementia Complex in 4 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is good evidence that the kynurenine pathway (KP) and one of its products, quinolinic acid (QUIN), play a role in the pathogenesis of neurological diseases, in particular AIDS dementia complex." | 3.71 | Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection. ( Armati, PJ; Brew, BJ; Croitoru, J; Guillemin, GJ; Kapoor, V; Kerr, SJ; Smith, DG; Smythe, GA, 2001) |
| " In addition, Tat, at similar concentrations, was toxic to human fetal neurons in culture." | 1.29 | Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity. ( Brownstone, RM; Geiger, JD; Knudsen, BE; Magnuson, DS; Nath, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Magnuson, DS | 1 |
| Knudsen, BE | 1 |
| Geiger, JD | 1 |
| Brownstone, RM | 1 |
| Nath, A | 1 |
| Baran, H | 1 |
| Hainfellner, JA | 1 |
| Kepplinger, B | 1 |
| Mazal, PR | 1 |
| Schmid, H | 1 |
| Budka, H | 1 |
| Guillemin, GJ | 1 |
| Kerr, SJ | 1 |
| Smythe, GA | 1 |
| Smith, DG | 1 |
| Kapoor, V | 1 |
| Armati, PJ | 1 |
| Croitoru, J | 1 |
| Brew, BJ | 1 |
| Schwarcz, R | 1 |
| Du, F | 1 |
1 review available for kynurenic acid and Acquired-Immune Deficiency Syndrome Dementia Complex
| Article | Year |
|---|---|
Quinolinic acid and kynurenic acid in the mammalian brain.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; AIDS Dementia Complex; Animals; Aspartic Acid; Biological Tra | 1991 |
3 other studies available for kynurenic acid and Acquired-Immune Deficiency Syndrome Dementia Complex
| Article | Year |
|---|---|
Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; AIDS Dementia Complex; Animals; Cells, Cultured; Cerebral Cortex; Dose- | 1995 |
Kynurenic acid metabolism in the brain of HIV-1 infected patients.
Topics: Adult; AIDS Dementia Complex; Brain; Cerebellum; Female; Frontal Lobe; HIV-1; Humans; Kynurenic Acid | 2000 |
Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection.
Topics: AIDS Dementia Complex; Astrocytes; Brain; Cells, Cultured; Cytokines; Enzymes; Fetus; Humans; Kynure | 2001 |