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kw 2189 and Lung Neoplasms

kw 2189 has been researched along with Lung Neoplasms in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asai, A; Iwamoto, Y; Kato, H; Kusaba, H; Mizukami, T; Nakano, H; Nishio, K; Saijo, N; Taguchi, F; Yano, K1
Funayama, Y; Isogai, Y; Kanzawa, F; Kuraishi, Y; Lee, YS; Nishio, K; Ogasawara, H; Ohira, T; Saijo, N1
Funayama, Y; Isogai, Y; Kubota, N; Kuraishi, Y; Nishio, K; Ogasawara, H; Ohira, T; Ohmori, T; Saijo, N; Takeda, Y1
Arioka, H; Fukuoka, K; Ishida, T; Nishio, K; Ogasawara, H; Saijo, N1

Other Studies

4 other study(ies) available for kw 2189 and Lung Neoplasms

ArticleYear
hnRNP L enhances sensitivity of the cells to KW-2189.
    International journal of cancer, 2004, Feb-20, Volume: 108, Issue:5

    Topics: Amino Acid Sequence; Animals; DNA-Binding Proteins; Duocarmycins; Heterogeneous-Nuclear Ribonucleoprotein L; Humans; Lung Neoplasms; Mice; Mutation; Nuclear Proteins; Pyrrolidinones; Ribonucleoproteins; Transfection; Tumor Cells, Cultured

2004
Intracellular carboxyl esterase activity is a determinant of cellular sensitivity to the antineoplastic agent KW-2189 in cell lines resistant to cisplatin and CPT-11.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Carboxylic Ester Hydrolases; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; DNA; Drug Resistance; Drug Resistance, Multiple; Duocarmycins; Female; Humans; Irinotecan; Lung Neoplasms; Microsomes; Ovarian Neoplasms; Pyrrolidinones; Tumor Cells, Cultured

1995
A novel antitumor antibiotic, KW-2189 is activated by carboxyl esterase and induces DNA strand breaks in human small cell lung cancer cells.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:4

    Topics: Antibiotics, Antineoplastic; Carboxylic Ester Hydrolases; Carcinoma, Small Cell; Cell Survival; DNA Damage; DNA, Neoplasm; Duocarmycins; Humans; In Vitro Techniques; Lung Neoplasms; Pyrrolidinones; Restriction Mapping; Tumor Cells, Cultured

1994
In vitro enhancement of antitumor activity of a water-soluble duocarmycin derivative, KW-2189, by caffeine-mediated DNA-repair inhibition in human lung cancer cells.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Caffeine; Carcinoma, Non-Small-Cell Lung; DNA Damage; DNA, Neoplasm; Drug Synergism; Duocarmycins; Humans; Lung Neoplasms; Pyrrolidinones; Solubility; Water

1997