Page last updated: 2024-09-04

kw 2189 and Carcinoma, Small Cell

kw 2189 has been researched along with Carcinoma, Small Cell in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Funayama, Y; Isogai, Y; Kanzawa, F; Kuraishi, Y; Lee, YS; Nishio, K; Ogasawara, H; Ohira, T; Saijo, N1
Funayama, Y; Isogai, Y; Kubota, N; Kuraishi, Y; Nishio, K; Ogasawara, H; Ohira, T; Ohmori, T; Saijo, N; Takeda, Y1

Other Studies

2 other study(ies) available for kw 2189 and Carcinoma, Small Cell

ArticleYear
Intracellular carboxyl esterase activity is a determinant of cellular sensitivity to the antineoplastic agent KW-2189 in cell lines resistant to cisplatin and CPT-11.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Carboxylic Ester Hydrolases; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; DNA; Drug Resistance; Drug Resistance, Multiple; Duocarmycins; Female; Humans; Irinotecan; Lung Neoplasms; Microsomes; Ovarian Neoplasms; Pyrrolidinones; Tumor Cells, Cultured

1995
A novel antitumor antibiotic, KW-2189 is activated by carboxyl esterase and induces DNA strand breaks in human small cell lung cancer cells.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:4

    Topics: Antibiotics, Antineoplastic; Carboxylic Ester Hydrolases; Carcinoma, Small Cell; Cell Survival; DNA Damage; DNA, Neoplasm; Duocarmycins; Humans; In Vitro Techniques; Lung Neoplasms; Pyrrolidinones; Restriction Mapping; Tumor Cells, Cultured

1994