kurarinone has been researched along with Parkinson-Disease* in 1 studies
1 other study(ies) available for kurarinone and Parkinson-Disease
Article | Year |
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Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model.
Parkinson's disease (PD) is one of the most common neurodegenerative disorders and is characterized by loss of dopaminergic neurons in the substantia nigra (SN), causing bradykinesia and rest tremors. Although the molecular mechanism of PD is still not fully understood, neuroinflammation has a key role in the damage of dopaminergic neurons. Herein, we found that kurarinone, a unique natural product from Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Epoxide Hydrolases; Flavonoids; Gene Deletion; Mice; Microglia; Parkinson Disease; Substrate Specificity | 2022 |