krn-7000 has been researched along with Bile-Duct-Diseases* in 1 studies
1 other study(ies) available for krn-7000 and Bile-Duct-Diseases
| Article | Year |
|---|---|
The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation.
Natural killer T (NKT) cells are activated by lipid antigens presented by CD1d molecules and represent a major lymphocyte subset of the liver. NODc3c4 mice spontaneously develop biliary inflammation in extra- and intrahepatic bile ducts. We demonstrated by flow cytometry that invariant NKT (iNKT) cells were more abundant in the thymus, spleen, and liver of NODc3c4 mice compared to NOD mice. iNKT cells in NODc3c4 mice displayed an activated phenotype. Further, NOD and NOD Topics: Animals; Antigens, CD1d; Bile Duct Diseases; Disease Models, Animal; Galactosylceramides; Inflammation; Liver; Mice; Mice, Knockout; Natural Killer T-Cells; Spleen; Thymus Gland | 2017 |