Page last updated: 2024-10-30

kojic acid and Skin Neoplasms

kojic acid has been researched along with Skin Neoplasms in 9 studies

Skin Neoplasms: Tumors or cancer of the SKIN.

Research Excerpts

ExcerptRelevanceReference
"Mannich bases of kojic acid derivatives may be promising therapeutic agents, since some have more potent effects on melanoma cells than previously FDA-approved drugs for the treatment of malignant melanoma."7.88Synthesis and Cytotoxic Evaluation of Kojic Acid Derivatives with Inhibitory Activity on Melanogenesis in Human Melanoma Cells. ( Aytemir, MD; Ercan, A; Karakaya, G; Oncul, S, 2018)
"Kojic acid is a natural product and normally used as a food additive and preservative, a skin-whitening agent in cosmetics, a plant growth regulator and a chemical intermediate."5.33Toxicogenomics of kojic acid on gene expression profiling of a375 human malignant melanoma cells. ( Chen, ST; Cheng, SL; Huang Liu, R; Sheu, JN; Sinchaikul, S; Tsay, GJ, 2006)
"Mannich bases of kojic acid derivatives may be promising therapeutic agents, since some have more potent effects on melanoma cells than previously FDA-approved drugs for the treatment of malignant melanoma."3.88Synthesis and Cytotoxic Evaluation of Kojic Acid Derivatives with Inhibitory Activity on Melanogenesis in Human Melanoma Cells. ( Aytemir, MD; Ercan, A; Karakaya, G; Oncul, S, 2018)
"Kojic acid (KA) has been widely used as a quasi-drug ingredient."1.34Kojic acid -absence of tumor-initiating activity in rat liver, and of carcinogenic and photo-genotoxic potential in mouse skin. ( Hara, T; Higa, Y; Kariya, K; Kawabe, M; Kitamoto, S; Nabae, K; Takahashi, M; Tanaka, N; Toda, Y, 2007)
"Kojic acid is a natural product and normally used as a food additive and preservative, a skin-whitening agent in cosmetics, a plant growth regulator and a chemical intermediate."1.33Toxicogenomics of kojic acid on gene expression profiling of a375 human malignant melanoma cells. ( Chen, ST; Cheng, SL; Huang Liu, R; Sheu, JN; Sinchaikul, S; Tsay, GJ, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Cardoso, R1
Valente, R1
Souza da Costa, CH1
da S Gonçalves Vianez, JL1
Santana da Costa, K1
de Molfetta, FA1
Nahum Alves, C1
Karakaya, G1
Ercan, A1
Oncul, S1
Aytemir, MD1
Park, MH1
Kim, SJ1
Jeong, HO1
Moon, KM1
Son, S1
Kim, DH1
Kim, HR1
Kim, MJ1
Yun, HY1
Chun, P2
Je, NK1
Yokozawa, T1
Moon, HR2
Chung, HY2
Chen, MJ1
Hung, CC1
Chen, YR1
Lai, ST1
Chan, CF1
Reddy, TL1
Garikapati, KR1
Reddy, SG1
Reddy, BV1
Yadav, JS1
Bhadra, U1
Bhadra, MP1
Tsujii, H1
Yamada, T1
Kajimoto, T1
Tanaka, R1
Tokuda, H1
Hasegawa, J1
Hamashima, Y1
Node, M1
Bae, SJ1
Ha, YM1
Park, YJ1
Park, JY1
Song, YM1
Ha, TK1
Cheng, SL1
Huang Liu, R1
Sheu, JN1
Chen, ST1
Sinchaikul, S1
Tsay, GJ1
Higa, Y1
Kawabe, M1
Nabae, K1
Toda, Y1
Kitamoto, S1
Hara, T1
Tanaka, N1
Kariya, K1
Takahashi, M1

Other Studies

9 other studies available for kojic acid and Skin Neoplasms

ArticleYear
Analysis of Kojic Acid Derivatives as Competitive Inhibitors of Tyrosinase: A Molecular Modeling Approach.
    Molecules (Basel, Switzerland), 2021, May-12, Volume: 26, Issue:10

    Topics: Catalytic Domain; Enzyme Inhibitors; Humans; Levodopa; Melanins; Melanocytes; Melanoma; Molecular Do

2021
Synthesis and Cytotoxic Evaluation of Kojic Acid Derivatives with Inhibitory Activity on Melanogenesis in Human Melanoma Cells.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:15

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mannich Bases; Me

2018
Inhibition of melanogenesis by 2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2-methylpropanoic acid (MHY908).
    Archives of pharmacal research, 2015, Volume: 38, Issue:4

    Topics: Agaricales; Animals; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Melanins; M

2015
Novel synthetic kojic acid-methimazole derivatives inhibit mushroom tyrosinase and melanogenesis.
    Journal of bioscience and bioengineering, 2016, Volume: 122, Issue:6

    Topics: Agaricales; Animals; Biphenyl Compounds; Chick Embryo; Enzyme Inhibitors; Melanins; Melanoma, Experi

2016
Simultaneous delivery of Paclitaxel and Bcl-2 siRNA via pH-Sensitive liposomal nanocarrier for the synergistic treatment of melanoma.
    Scientific reports, 2016, 10-27, Volume: 6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Drug Compounding; Drug Deli

2016
Hybrids of 3alpha-methoxyserrat-14-en-21beta-ol (PJ-1) and 3beta-methoxyserrat-14-en-21beta-ol (PJ-2) and various anti-oxidants as cancer chemopreventive agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: Animals; Antigens, Viral; Antineoplastic Agents; Antioxidants; Cell Line; Drug Screening Assays, Ant

2010
Design, synthesis, and evaluation of (E)-N-substituted benzylidene-aniline derivatives as tyrosinase inhibitors.
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Agaricales; alpha-MSH; Aniline Compounds; Animals; Antineoplastic Agents; Benzylidene Compounds; Cat

2012
Toxicogenomics of kojic acid on gene expression profiling of a375 human malignant melanoma cells.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:4

    Topics: Antioxidants; Cell Line, Tumor; Cell Survival; Computational Biology; Gene Amplification; Gene Expre

2006
Kojic acid -absence of tumor-initiating activity in rat liver, and of carcinogenic and photo-genotoxic potential in mouse skin.
    The Journal of toxicological sciences, 2007, Volume: 32, Issue:2

    Topics: Administration, Oral; Animals; Antioxidants; Carcinogenicity Tests; Carcinogens; CHO Cells; Cricetin

2007