kojic acid has been researched along with Malignant Melanoma in 22 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mannich bases of kojic acid derivatives may be promising therapeutic agents, since some have more potent effects on melanoma cells than previously FDA-approved drugs for the treatment of malignant melanoma." | 7.88 | Synthesis and Cytotoxic Evaluation of Kojic Acid Derivatives with Inhibitory Activity on Melanogenesis in Human Melanoma Cells. ( Aytemir, MD; Ercan, A; Karakaya, G; Oncul, S, 2018) |
| "Although the toxicogenomics of kojic acid treated A375 human malignant melanoma cells has been elucidated, the proteomics of cellular response is still poorly understood." | 7.74 | Proteomics analysis of kojic acid treated A375 human malignant melanoma cells. ( Chen, ST; Cheng, SL; Huang-Liu, R; Kao, SH; Liao, HH; Nawarak, J; Sinchaikul, S, 2008) |
| "the sesamol- and kojic-treated SK-MEL2 cells." | 5.40 | Application of FTIR microspectroscopy for characterization of biomolecular changes in human melanoma cells treated by sesamol and kojic acid. ( Barusrux, S; Srisayam, M; Tanthanuch, W; Thumanu, K; Weerapreeyakul, N, 2014) |
| "Kojic acid is a natural product and normally used as a food additive and preservative, a skin-whitening agent in cosmetics, a plant growth regulator and a chemical intermediate." | 5.33 | Toxicogenomics of kojic acid on gene expression profiling of a375 human malignant melanoma cells. ( Chen, ST; Cheng, SL; Huang Liu, R; Sheu, JN; Sinchaikul, S; Tsay, GJ, 2006) |
| "Mannich bases of kojic acid derivatives may be promising therapeutic agents, since some have more potent effects on melanoma cells than previously FDA-approved drugs for the treatment of malignant melanoma." | 3.88 | Synthesis and Cytotoxic Evaluation of Kojic Acid Derivatives with Inhibitory Activity on Melanogenesis in Human Melanoma Cells. ( Aytemir, MD; Ercan, A; Karakaya, G; Oncul, S, 2018) |
| "the sesamol- and kojic-treated SK-MEL2 cells." | 1.40 | Application of FTIR microspectroscopy for characterization of biomolecular changes in human melanoma cells treated by sesamol and kojic acid. ( Barusrux, S; Srisayam, M; Tanthanuch, W; Thumanu, K; Weerapreeyakul, N, 2014) |
| "Kojic acid is a natural product and normally used as a food additive and preservative, a skin-whitening agent in cosmetics, a plant growth regulator and a chemical intermediate." | 1.33 | Toxicogenomics of kojic acid on gene expression profiling of a375 human malignant melanoma cells. ( Chen, ST; Cheng, SL; Huang Liu, R; Sheu, JN; Sinchaikul, S; Tsay, GJ, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 11 (50.00) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Criton, M | 1 |
| Le Mellay-Hamon, V | 1 |
| Yamazaki, Y | 1 |
| Kawano, Y | 1 |
| Yamanaka, A | 1 |
| Maruyama, S | 1 |
| Nam, JH | 1 |
| Nam, DY | 1 |
| Lee, DU | 1 |
| Ferro, S | 1 |
| De Luca, L | 1 |
| Germanò, MP | 1 |
| Buemi, MR | 1 |
| Ielo, L | 1 |
| Certo, G | 1 |
| Kanteev, M | 1 |
| Fishman, A | 1 |
| Rapisarda, A | 1 |
| Gitto, R | 1 |
| Ullah, S | 1 |
| Kang, D | 1 |
| Lee, S | 1 |
| Ikram, M | 1 |
| Park, C | 1 |
| Park, Y | 1 |
| Yoon, S | 1 |
| Chun, P | 1 |
| Moon, HR | 1 |
| Santi, MD | 1 |
| Peralta, MA | 1 |
| Puiatti, M | 1 |
| Cabrera, JL | 1 |
| Ortega, MG | 1 |
| Nazir, Y | 1 |
| Saeed, A | 1 |
| Rafiq, M | 1 |
| Afzal, S | 1 |
| Ali, A | 1 |
| Latif, M | 1 |
| Zuegg, J | 1 |
| Hussein, WM | 1 |
| Fercher, C | 1 |
| Barnard, RT | 1 |
| Cooper, MA | 1 |
| Blaskovich, MAT | 1 |
| Ashraf, Z | 1 |
| Ziora, ZM | 1 |
| Roulier, B | 1 |
| Pérès, B | 1 |
| Haudecoeur, R | 1 |
| Vanjare, BD | 1 |
| Choi, NG | 1 |
| Mahajan, PG | 1 |
| Raza, H | 2 |
| Hassan, M | 2 |
| Han, Y | 1 |
| Yu, SM | 1 |
| Kim, SJ | 2 |
| Seo, SY | 2 |
| Lee, KH | 1 |
| Cardoso, R | 1 |
| Valente, R | 1 |
| Souza da Costa, CH | 1 |
| da S Gonçalves Vianez, JL | 1 |
| Santana da Costa, K | 1 |
| de Molfetta, FA | 1 |
| Nahum Alves, C | 1 |
| Abbas, Q | 1 |
| Phull, AR | 1 |
| Karakaya, G | 1 |
| Ercan, A | 1 |
| Oncul, S | 1 |
| Aytemir, MD | 1 |
| Peng, M | 1 |
| Wang, Y | 1 |
| Fu, Q | 1 |
| Sun, F | 1 |
| Na, N | 1 |
| Ouyang, J | 1 |
| Micillo, R | 1 |
| Sirés-Campos, J | 1 |
| García-Borrón, JC | 1 |
| Panzella, L | 1 |
| Napolitano, A | 1 |
| Olivares, C | 1 |
| Srisayam, M | 1 |
| Weerapreeyakul, N | 1 |
| Barusrux, S | 1 |
| Tanthanuch, W | 1 |
| Thumanu, K | 1 |
| Nawarak, J | 1 |
| Huang-Liu, R | 1 |
| Kao, SH | 1 |
| Liao, HH | 1 |
| Sinchaikul, S | 2 |
| Chen, ST | 2 |
| Cheng, SL | 2 |
| Li, X | 1 |
| Guo, L | 1 |
| Sun, Y | 1 |
| Zhou, J | 1 |
| Gu, Y | 1 |
| Li, Y | 1 |
| Miyake, M | 1 |
| Yamamoto, S | 1 |
| Sano, O | 1 |
| Fujii, M | 1 |
| Kohno, K | 1 |
| Ushio, S | 1 |
| Iwaki, K | 1 |
| Fukuda, S | 1 |
| Kim, DH | 1 |
| Hwang, JS | 1 |
| Baek, HS | 1 |
| Kim, KJ | 1 |
| Lee, BG | 1 |
| Chang, I | 1 |
| Kang, HH | 1 |
| Lee, OS | 1 |
| Huang Liu, R | 1 |
| Sheu, JN | 1 |
| Tsay, GJ | 1 |
| Kobayashi, R | 1 |
| Takisada, M | 1 |
| Suzuki, T | 1 |
| Kirimura, K | 1 |
| Usami, S | 1 |
| Mishima, Y | 1 |
2 reviews available for kojic acid and Malignant Melanoma
| Article | Year |
|---|---|
Advances in the Design of Genuine Human Tyrosinase Inhibitors for Targeting Melanogenesis and Related Pigmentations.
Topics: Agaricales; Amino Acid Sequence; Biological Factors; Drug Delivery Systems; Drug Design; Enzyme Inhi | 2020 |
A post melanosomal era: control of melanogenesis and melanoma growth.
Topics: Adolescent; Animals; Boron; Boron Compounds; Cricetinae; Fatty Acids, Unsaturated; Gene Expression R | 1992 |
20 other studies available for kojic acid and Malignant Melanoma
| Article | Year |
|---|---|
Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation.
Topics: Agaricales; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Inhibitory Concentration 50 | 2008 |
N-[(Dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Enz | 2009 |
Valencene from the Rhizomes of Cyperus rotundus Inhibits Skin Photoaging-Related Ion Channels and UV-Induced Melanogenesis in B16F10 Melanoma Cells.
Topics: Animals; Cyperus; Melanins; Melanoma; Mice; Molecular Structure; Republic of Korea; Rhizome; Sesquit | 2016 |
Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors.
Topics: Agaricales; Binding, Competitive; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Melanoma | 2017 |
Synthesis of cinnamic amide derivatives and their anti-melanogenic effect in α-MSH-stimulated B16F10 melanoma cells.
Topics: Agaricales; Amides; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cinnamates; Dose-Respo | 2019 |
Melanogenic inhibitory effects of Triangularin in B16F0 melanoma cells, in vitro and molecular docking studies.
Topics: Humans; Melanoma; Molecular Docking Simulation | 2019 |
Hydroxyl substituted benzoic acid/cinnamic acid derivatives: Tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies.
Topics: Benzoic Acid; Cinnamates; Humans; Melanoma; Molecular Docking Simulation; Structure-Activity Relatio | 2020 |
Novel 1,3,4-oxadiazole compounds inhibit the tyrosinase and melanin level: Synthesis, in-vitro, and in-silico studies.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Humans; Melanins; Melanoma; Models, Molecula | 2021 |
Analysis of Kojic Acid Derivatives as Competitive Inhibitors of Tyrosinase: A Molecular Modeling Approach.
Topics: Catalytic Domain; Enzyme Inhibitors; Humans; Levodopa; Melanins; Melanocytes; Melanoma; Molecular Do | 2021 |
Acetazolamide Inhibits the Level of Tyrosinase and Melanin: An Enzyme Kinetic, In Vitro, In Vivo, and In Silico Studies.
Topics: Acetazolamide; Agaricales; Animals; Cell Line, Tumor; Cell Survival; Computer Simulation; Enzyme Inh | 2017 |
Synthesis and Cytotoxic Evaluation of Kojic Acid Derivatives with Inhibitory Activity on Melanogenesis in Human Melanoma Cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mannich Bases; Me | 2018 |
Melanosome-Targeting Near-Infrared Fluorescent Probe with Large Stokes Shift for in Situ Quantification of Tyrosinase Activity and Assessing Drug Effects on Differently Invasive Melanoma Cells.
Topics: Ficusin; Fluorescent Dyes; Humans; Infrared Rays; Melanoma; Melanosomes; Monophenol Monooxygenase; N | 2018 |
Conjugation with Dihydrolipoic Acid Imparts Caffeic Acid Ester Potent Inhibitory Effect on Dopa Oxidase Activity of Human Tyrosinase.
Topics: Agaricales; Caffeic Acids; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme | 2018 |
Application of FTIR microspectroscopy for characterization of biomolecular changes in human melanoma cells treated by sesamol and kojic acid.
Topics: Benzodioxoles; Cell Line, Tumor; Cell Survival; Humans; Melanoma; Phenols; Principal Component Analy | 2014 |
Proteomics analysis of kojic acid treated A375 human malignant melanoma cells.
Topics: Base Sequence; Blotting, Western; Cell Line, Tumor; DNA Primers; Electrophoresis, Gel, Two-Dimension | 2008 |
Baicalein inhibits melanogenesis through activation of the ERK signaling pathway.
Topics: Animals; Cell Death; Cell Line, Tumor; Cell Survival; Down-Regulation; Enzyme Activation; Extracellu | 2010 |
Inhibitory effects of 2-amino-3H-phenoxazin-3-one on the melanogenesis of murine B16 melanoma cell line.
Topics: Agaricales; Animals; Cell Line, Tumor; Indoles; Melanins; Melanoma; Melanoma, Experimental; Mice; Mi | 2010 |
Development of 5-[(3-aminopropyl)phosphinooxy]-2-(hydroxymethyl)-4H-pyran-4-one as a novel whitening agent.
Topics: Animals; Dermatologic Agents; Female; Guinea Pigs; Humans; Melanins; Melanocytes; Melanoma; Mice; Py | 2003 |
Toxicogenomics of kojic acid on gene expression profiling of a375 human malignant melanoma cells.
Topics: Antioxidants; Cell Line, Tumor; Cell Survival; Computational Biology; Gene Amplification; Gene Expre | 2006 |
Neoagarobiose as a novel moisturizer with whitening effect.
Topics: Animals; Arbutin; Disaccharides; Melanoma; Mice; Pyrones; Skin Care; Tumor Cells, Cultured; Wettabil | 1997 |