knk-437 has been researched along with Peritoneal-Neoplasms* in 1 studies
1 other study(ies) available for knk-437 and Peritoneal-Neoplasms
| Article | Year |
|---|---|
Nuclear heat shock protein 110 expression is associated with poor prognosis and hyperthermo-chemotherapy resistance in gastric cancer patients with peritoneal metastasis.
To investigate the significance of heat shock protein 110 (HSP110) in gastric cancer (GC) patients with peritoneal metastasis undergoing hyperthermo-chemotherapy.. Primary GC patients (. HSP110 immnohistochemical staining in 14 GC patients showed that five (35.7%) samples belonged to the low expression group, and nine (64.3%) samples belonged to the high expression group. Progression-free survival was significantly shorter in the HSP110 high-expression group than in the low-expression group (. The expression of nuclear HSP110 in GC patients might be a new marker of chemosensitivity and a therapeutic target for patients who are tolerant to existing hyperthermo-chemotherapies. Topics: Antineoplastic Agents; Benzhydryl Compounds; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Female; HSP110 Heat-Shock Proteins; Humans; Hyperthermia, Induced; Male; Middle Aged; Peritoneal Neoplasms; Peritoneum; Pyrrolidinones; Stomach Neoplasms | 2017 |