kl001 and Obesity

kl001 has been researched along with Obesity* in 1 studies

Other Studies

1 other study(ies) available for kl001 and Obesity

Article	Year
Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents. Bioorganic & medicinal chemistry letters, 2018, 02-01, Volume: 28, Issue:3 A series of novel carbazole-containing amides and ureas were synthesized. A structure-activity relationship study of these compounds led to the identification of potent cryptochrome modulators. Based on the desired pharmacokinetic/pharmacodynamic parameters and the results of efficacy studies in db/db mice, compound 50 was selected for further profiling. Topics: Amides; Animals; Carbazoles; Cryptochromes; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Discovery; Hypoglycemic Agents; Male; Mice; Molecular Structure; Obesity; Structure-Activity Relationship; Urea	2018

Article

Year

Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents.

Bioorganic & medicinal chemistry letters, 2018, 02-01, Volume: 28, Issue:3

A series of novel carbazole-containing amides and ureas were synthesized. A structure-activity relationship study of these compounds led to the identification of potent cryptochrome modulators. Based on the desired pharmacokinetic/pharmacodynamic parameters and the results of efficacy studies in db/db mice, compound 50 was selected for further profiling.

Topics: Amides; Animals; Carbazoles; Cryptochromes; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Discovery; Hypoglycemic Agents; Male; Mice; Molecular Structure; Obesity; Structure-Activity Relationship; Urea

2018