kiss1-protein--human and Uterine-Hemorrhage

To investigate the association between kisspeptin 10 (Kp-10) levels and early pregnancy bleeding and perinatal outcome.. A total of 20 pregnant women with the complaint of vaginal bleeding during 7-18 gestational weeks and 20 healthy gestational week matched pregnant women were included in the study. Maternal plasma Kp-10 levels were measured with the enzyme immunoassay method. Adverse pregnancy outcomes like intrauterine growth restriction, preterm delivery, preeclampsia and low birth weight were evaluated in both groups.. Maternal plasma Kp-10 levels (p = 0.01) and birth weight (p = 0.06) were found to be lower in women with bleeding. Intrauterine growth restriction, preterm delivery and intrauterine exitus were noted more commonly in women with bleeding (10 vs. 0%, 25 vs. 15% and 20 vs. 0%, p = 0.08). Preeclampsia were developed in 5% of both groups. Kp-10 levels showed positive correlation with gestational week (p = 0.02) and ALT levels (p = 0.02).. [corrected] Kp-10 levels were found lower in women with early pregnancy bleeding.

Topics: Abortion, Threatened; Adult; Alanine Transaminase; Female; Fetal Growth Retardation; Humans; Infant, Low Birth Weight; Infant, Newborn; Kisspeptins; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Premature Birth; Uterine Hemorrhage; Young Adult