Page last updated: 2024-10-30

kinetin and Neoplasms

kinetin has been researched along with Neoplasms in 13 studies

Kinetin: A furanyl adenine found in PLANTS and FUNGI. It has plant growth regulation effects.
cytokinin : A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots.
kinetin : A member of the class of 6-aminopurines that is adenine carrying a (furan-2-ylmethyl) substituent at the exocyclic amino group.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Metabolism of cancer cells is predominantly based on the Crabtree effect that relies on glucose-induced inhibition of cell respiration and thus on oxidative phosphorylation (OXPHOS), which supports the survival of cancer cells in metabolic stress conditions."1.56Circumventing the Crabtree effect: forcing oxidative phosphorylation (OXPHOS) via galactose medium increases sensitivity of HepG2 cells to the purine derivative kinetin riboside. ( Fedoruk-Wyszomirska, A; Gurda-Wozna, D; Orlicka-Płocka, M; Wyszko, E, 2020)
"Kinetin riboside (KR) is a N6-substituted derivative of adenosine."1.37Effects of kinetin riboside on proliferation and proapoptotic activities in human normal and cancer cell lines. ( Barciszewski, J; Dudzik, P; Dulińska-Litewka, J; Jędrychowska, P; Laidler, P; Opałka, M; Wyszko, E, 2011)
"Kinetin riboside was shown to only act on M4 Beu human and B16 murine melanoma cells at low concentration (1."1.32Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells. ( Bos, R; Griffaut, B; Ledoigt, G; Madelmont, JC; Maurizis, JC, 2004)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Wawrzyniak, D1
Rolle, K1
Barciszewski, J2
Orlicka-Płocka, M1
Gurda-Wozna, D1
Fedoruk-Wyszomirska, A1
Wyszko, E2
Sevimli-Gur, C1
Cetin, B1
Akay, S1
Gulce-Iz, S1
Yesil-Celiktas, O1
Wandl, S1
Wesierska-Gadek, J1
Dvořák, Z1
Starha, P1
Trávníček, Z1
Dudzik, P1
Dulińska-Litewka, J1
Jędrychowska, P1
Opałka, M1
Laidler, P1
CZIHARZ, H1
BRUCKER, W1
SCHAEFFER, GW1
Griffaut, B1
Bos, R1
Maurizis, JC1
Madelmont, JC1
Ledoigt, G1
Choi, BH1
Kim, W1
Wang, QC1
Kim, DC1
Tan, SN1
Yong, JW1
Kim, KT1
Yoon, HS1
Buquet-Fagot, C1
Lallemand, F1
Montagne, MN1
Mester, J1
Simon, KH1

Reviews

2 reviews available for kinetin and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Biological activity of N6-furfuryladenosine
    Postepy biochemii, 2019, 06-06, Volume: 65, Issue:2

    Topics: Adenosine; Apoptosis; Kinetin; Neoplasms; Plant Growth Regulators; Plants

2019

Other Studies

11 other studies available for kinetin and Neoplasms

ArticleYear
Circumventing the Crabtree effect: forcing oxidative phosphorylation (OXPHOS) via galactose medium increases sensitivity of HepG2 cells to the purine derivative kinetin riboside.
    Apoptosis : an international journal on programmed cell death, 2020, Volume: 25, Issue:11-12

    Topics: Adenosine; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Culture Media; Galactose; Gluco

2020
Extracts from black carrot tissue culture as potent anticancer agents.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2013, Volume: 68, Issue:3

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Anthocyanins; Antineoplastic Agents, Phytogenic; Breast Neo

2013
Is olomoucine, a weak CDK2 inhibitor, able to induce apoptosis in cancer cells?
    Annals of the New York Academy of Sciences, 2009, Volume: 1171

    Topics: Apoptosis; Caspase 3; Caspase 7; Cell Cycle; Cyclin-Dependent Kinase 2; DNA, Neoplasm; Dose-Response

2009
Evaluation of in vitro cytotoxicity of 6-benzylaminopurine carboplatin derivatives against human cancer cell lines and primary human hepatocytes.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:3

    Topics: Adult; Antineoplastic Agents; Benzyl Compounds; Carboplatin; Cell Line, Tumor; Cell Survival; Cispla

2011
Effects of kinetin riboside on proliferation and proapoptotic activities in human normal and cancer cell lines.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:8

    Topics: Adenosine; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Proli

2011
[On the influence of kinetin and indolyl-3-butyric acid on the callus and crown-gall tissue of Datura and Daucus in vitro].
    Acta biologica et medica Germanica, 1962, Volume: 8

    Topics: Alkaloids; Butyric Acid; Crowns; Datura; Datura stramonium; Growth Substances; In Vitro Techniques;

1962
Tumour induction by an indolyl-3-acetic acid-kinetin interaction in a Nicotiana hybrid.
    Nature, 1962, Dec-29, Volume: 196

    Topics: Indoleacetic Acids; Kinetin; Neoplasms; Neoplasms, Experimental; Nicotiana; Plant Growth Regulators

1962
Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells.
    International journal of biological macromolecules, 2004, Volume: 34, Issue:4

    Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans;

2004
Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells.
    Cancer letters, 2008, Mar-08, Volume: 261, Issue:1

    Topics: Adenosine; Animals; Apoptosis; bcl-Associated Death Protein; Caspase 3; Cattle; Cell Line; Cell Line

2008
Effects of olomoucine, a selective inhibitor of cyclin-dependent kinases, on cell cycle progression in human cancer cell lines.
    Anti-cancer drugs, 1997, Volume: 8, Issue:6

    Topics: Cell Cycle; Cell Division; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Kinetin; Lovastatin;

1997
[Importance of growth-promoting substances in the therapy of cancer].
    Medizinische Monatsschrift, 1974, Volume: 28, Issue:6

    Topics: Aldehydes; Alkaloids; Amidines; Ethyl Ethers; Glycosides; Glyoxal; Growth Inhibitors; Growth Substan

1974