kinetin has been researched along with Dominant Hereditary Sensory Neuropathy, Type III in 13 studies
Kinetin: A furanyl adenine found in PLANTS and FUNGI. It has plant growth regulation effects.
cytokinin : A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots.
kinetin : A member of the class of 6-aminopurines that is adenine carrying a (furan-2-ylmethyl) substituent at the exocyclic amino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pridopidine has an additive effect on IKAP levels when used in combination with kinetin or TSA, but not with PS; suggesting that PS and pridopidine influence IKBKAP levels through the same mechanism." | 1.51 | Combinatorial treatment increases IKAP levels in human cells generated from Familial Dysautonomia patients. ( Ast, G; Donyo, M; Yannai, S; Zonszain, J, 2019) |
| " In the highest dosing cohorts (23." | 1.35 | Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. ( Axelrod, FB; Gold-von Simson, G; Goldberg, JD; Leyne, M; Mull, J; Rolnitzky, LM; Slaugenhaupt, SA; Voustianiouk, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Morini, E | 3 |
| Chekuri, A | 1 |
| Logan, EM | 1 |
| Bolduc, JM | 1 |
| Kirchner, EG | 1 |
| Salani, M | 3 |
| Krauson, AJ | 1 |
| Narasimhan, J | 2 |
| Gabbeta, V | 2 |
| Grover, S | 1 |
| Dakka, A | 2 |
| Mollin, A | 1 |
| Jung, SP | 1 |
| Zhao, X | 2 |
| Zhang, N | 1 |
| Zhang, S | 1 |
| Arnold, M | 1 |
| Woll, MG | 1 |
| Naryshkin, NA | 2 |
| Weetall, M | 2 |
| Slaugenhaupt, SA | 7 |
| Urbina, F | 1 |
| Brenner, A | 1 |
| Shetty, R | 1 |
| Gallagher, CS | 1 |
| Law, EA | 1 |
| Sunshine, S | 1 |
| Finneran, DJ | 1 |
| Johnson, G | 1 |
| Minor, L | 1 |
| Yannai, S | 1 |
| Zonszain, J | 1 |
| Donyo, M | 1 |
| Ast, G | 1 |
| Gao, D | 1 |
| Montgomery, CM | 1 |
| Mazzasette, C | 1 |
| Krussig, TA | 1 |
| Swain, B | 1 |
| Dietrich, P | 1 |
| Hedrick, J | 1 |
| Wojtkiewicz, GG | 1 |
| Ko, CP | 1 |
| Talkowski, ME | 1 |
| Dragatsis, I | 1 |
| Lefler, S | 1 |
| Cohen, MA | 1 |
| Kantor, G | 1 |
| Cheishvili, D | 1 |
| Even, A | 1 |
| Birger, A | 1 |
| Turetsky, T | 1 |
| Gil, Y | 1 |
| Even-Ram, S | 1 |
| Aizenman, E | 1 |
| Bashir, N | 1 |
| Maayan, C | 1 |
| Razin, A | 1 |
| Reubinoff, BE | 1 |
| Weil, M | 1 |
| Gold-von Simson, G | 2 |
| Goldberg, JD | 1 |
| Rolnitzky, LM | 1 |
| Mull, J | 4 |
| Leyne, M | 4 |
| Voustianiouk, A | 1 |
| Axelrod, FB | 4 |
| Lee, G | 2 |
| Papapetrou, EP | 1 |
| Kim, H | 1 |
| Chambers, SM | 1 |
| Tomishima, MJ | 1 |
| Fasano, CA | 1 |
| Ganat, YM | 1 |
| Menon, J | 1 |
| Shimizu, F | 1 |
| Viale, A | 1 |
| Tabar, V | 1 |
| Sadelain, M | 1 |
| Studer, L | 2 |
| Liebes, L | 1 |
| Mendoza, S | 1 |
| Norcliffe-Kaufmann, L | 1 |
| Kaufmann, H | 1 |
| Boone, N | 1 |
| Bergon, A | 1 |
| Loriod, B | 1 |
| Devèze, A | 1 |
| Nguyen, C | 1 |
| Ibrahim, EC | 2 |
| Cuajungco, MP | 1 |
| Gill, SP | 1 |
| Hims, MM | 2 |
| Quintero, F | 1 |
| Gusella, JF | 2 |
| Luft, FC | 1 |
| Liu, L | 1 |
| Lazaro, C | 1 |
| Shetty, RS | 1 |
| Gill, S | 1 |
| Reed, R | 1 |
1 review available for kinetin and Dominant Hereditary Sensory Neuropathy, Type III
| Article | Year |
|---|---|
Better days are coming for Riley-Day patients.
Topics: Alternative Splicing; Dysautonomia, Familial; Humans; Kinetin | 2007 |
12 other studies available for kinetin and Dominant Hereditary Sensory Neuropathy, Type III
| Article | Year |
|---|---|
Development of an oral treatment that rescues gait ataxia and retinal degeneration in a phenotypic mouse model of familial dysautonomia.
Topics: Administration, Oral; Animals; Dysautonomia, Familial; Gait Ataxia; Kinetin; Mice; Neurodegenerative | 2023 |
Development of a Screening Platform to Identify Small Molecules That Modify ELP1 Pre-mRNA Splicing in Familial Dysautonomia.
Topics: Cell Line; Cytokinins; Drug Evaluation, Preclinical; Dysautonomia, Familial; Exons; HEK293 Cells; Hu | 2019 |
Combinatorial treatment increases IKAP levels in human cells generated from Familial Dysautonomia patients.
Topics: Brain-Derived Neurotrophic Factor; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Dr | 2019 |
ELP1 Splicing Correction Reverses Proprioceptive Sensory Loss in Familial Dysautonomia.
Topics: Alleles; Animals; Behavior, Animal; Cell Line; Crosses, Genetic; Disease Models, Animal; Dysautonomi | 2019 |
Familial Dysautonomia (FD) Human Embryonic Stem Cell Derived PNS Neurons Reveal that Synaptic Vesicular and Neuronal Transport Genes Are Directly or Indirectly Affected by IKBKAP Downregulation.
Topics: Biological Transport; Carrier Proteins; Cell Differentiation; Down-Regulation; Dysautonomia, Familia | 2015 |
Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing.
Topics: Adult; Alternative Splicing; Carrier Proteins; Dose-Response Relationship, Drug; Dysautonomia, Famil | 2009 |
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.
Topics: Adolescent; Alternative Splicing; Animals; Carrier Proteins; Cell Dedifferentiation; Cell Differenti | 2009 |
Modelling familial dysautonomia in human induced pluripotent stem cells.
Topics: Biomedical Research; Cell Culture Techniques; Cell Line; Dysautonomia, Familial; Genetic Therapy; Hu | 2011 |
Kinetin improves IKBKAP mRNA splicing in patients with familial dysautonomia.
Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Carrier Proteins; Dysautonomia, | 2011 |
Genome-wide analysis of familial dysautonomia and kinetin target genes with patient olfactory ecto-mesenchymal stem cells.
Topics: Adolescent; Carrier Proteins; Cell Differentiation; Cells, Cultured; Child; Dysautonomia, Familial; | 2012 |
Rescue of a human mRNA splicing defect by the plant cytokinin kinetin.
Topics: Adenine; Alternative Splicing; Carrier Proteins; Cells, Cultured; Cytokinins; Dysautonomia, Familial | 2004 |
Therapeutic potential and mechanism of kinetin as a treatment for the human splicing disease familial dysautonomia.
Topics: Carrier Proteins; Cell Line, Tumor; Dysautonomia, Familial; Exons; Humans; Kinetin; Neurofibromatose | 2007 |