ki16425 and Fibrosis

ki16425 has been researched along with Fibrosis* in 1 studies

Other Studies

1 other study(ies) available for ki16425 and Fibrosis

Article	Year
Synthesis and evaluation of isoxazole derivatives as lysophosphatidic acid (LPA) antagonists. Bioorganic & medicinal chemistry letters, 2007, Jul-01, Volume: 17, Issue:13 A series of isoxazole derivatives were synthesized and their antagonistic activities against LPA stimulation on both LPA(1)/CHO cells and rHSC cells were evaluated. Among them, 3-(4-[4-[1-(2-chloro-cyclopent-1-enyl)-ethoxycarbonylamino]-isoxazol-3- y]]-benzylsulfanyl)-propionic acid (34) showed the most potent activities. Topics: Animals; Cell Proliferation; Chemistry, Pharmaceutical; CHO Cells; Cricetinae; Cricetulus; Drug Design; Fibrosis; Humans; Inhibitory Concentration 50; Isoxazoles; Liver; Lysophospholipids; Propionates; Rats	2007

Article

Year

Synthesis and evaluation of isoxazole derivatives as lysophosphatidic acid (LPA) antagonists.

Bioorganic & medicinal chemistry letters, 2007, Jul-01, Volume: 17, Issue:13

A series of isoxazole derivatives were synthesized and their antagonistic activities against LPA stimulation on both LPA(1)/CHO cells and rHSC cells were evaluated. Among them, 3-(4-[4-[1-(2-chloro-cyclopent-1-enyl)-ethoxycarbonylamino]-isoxazol-3- y]]-benzylsulfanyl)-propionic acid (34) showed the most potent activities.

Topics: Animals; Cell Proliferation; Chemistry, Pharmaceutical; CHO Cells; Cricetinae; Cricetulus; Drug Design; Fibrosis; Humans; Inhibitory Concentration 50; Isoxazoles; Liver; Lysophospholipids; Propionates; Rats

2007