Page last updated: 2024-10-30

khellin and Syndrome

khellin has been researched along with Syndrome in 13 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"Keloids are proliferative fibrous growths that result from an excessive tissue response to skin trauma."1.31Clinical genetics of familial keloids. ( Marneros, AG; Norris, JE; Olsen, BR; Reichenberger, E, 2001)
"The syndrome of torticollis, keloids, cryptorchidism and renal dysplasia was described by Goeminne (1968) in a large family, and listed as X-linked incomplete dominant by McKusick (1978; No."1.26Gene mapping and serendipity. The locus for torticollis, keloids, cryptorchidism and renal dysplasia (31430, Mckusick) is at Xq28, distal to the G6PD locus. ( Fraccaro, M; Zuffardi, O, 1982)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's2 (15.38)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atwal, PS1
Blease, S1
Braxton, A1
Graves, J1
He, W1
Person, R1
Slattery, L1
Bernstein, JA1
Hudgins, L1
Heyen, CA1
Delk, PR1
Bull, MJ1
Weaver, DD1
Eberwein, P1
Reinhard, T1
Agostini, H1
Poloschek, CM1
Guthoff, R1
Auw-Haedrich, C1
Fryns, JP1
Gevers, D1
DESFORGES, JA1
Zuffardi, O1
Fraccaro, M1
Zaĭtseva, SIu1
Trofimova, IB1
Paradisi, M1
Angelo, C1
Conti, G1
Mostaccioli, S1
Cianchini, G1
Atzori, F1
Puddu, P1
Elia, M1
Di Lello, R1
Romano, C1
Schepis, C1
Marneros, AG1
Norris, JE1
Olsen, BR1
Reichenberger, E1
Elsas, FJ1
Green, WR1
Rumi, TK1
Kapkaev, RA1
Sampaio, MM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Identification of Genetic Variants That Contribute to Keloid Formation in Families and Isolated Cases.[NCT01619553]7,000 participants (Anticipated)Observational2009-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

13 other studies available for khellin and Syndrome

ArticleYear
Novel X-linked syndrome of cardiac valvulopathy, keloid scarring, and reduced joint mobility due to filamin A substitution G1576R.
    American journal of medical genetics. Part A, 2016, Volume: 170A, Issue:4

    Topics: Adult; Alleles; Amino Acid Substitution; Codon; Facies; Filamins; Genetic Association Studies; Genet

2016
A report of an apparent new genetic syndrome consisting of joint contractures, keloids, large optic cup-to-disc ratio and renal stones.
    American journal of medical genetics. Part A, 2008, Dec-15, Volume: 146A, Issue:24

    Topics: Abnormalities, Multiple; Adult; Child; Contracture; Female; Humans; Joints; Keloid; Kidney Calculi;

2008
[Intensive intracorneal keloid formation in a case of Peters plus syndrome and in Peters anomaly with maximum manifestation].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2010, Volume: 107, Issue:2

    Topics: Abnormalities, Multiple; Cataract; Cornea; Corneal Diseases; Eye Abnormalities; Female; Humans; Infa

2010
Goeminne syndrome (OMIM 314300): another male patient 30 years later.
    Genetic counseling (Geneva, Switzerland), 2003, Volume: 14, Issue:1

    Topics: Abnormalities, Multiple; Adult; Cervical Vertebrae; Chromosomes, Human, X; Cryptorchidism; Follow-Up

2003
Non-surgical reduction of granuloma and keloids.
    Journal of the American Podiatry Association, 1958, Volume: 48, Issue:8

    Topics: Fibroma; Foot; Foot Diseases; Granuloma; Humans; Hydrocortisone; Keloid; Neoplasms; Syndrome

1958
Gene mapping and serendipity. The locus for torticollis, keloids, cryptorchidism and renal dysplasia (31430, Mckusick) is at Xq28, distal to the G6PD locus.
    Human genetics, 1982, Volume: 62, Issue:3

    Topics: Abnormalities, Multiple; Chromosome Mapping; Cryptorchidism; Female; Glucosephosphate Dehydrogenase;

1982
[2 cases of keloid diathesis in one family].
    Vestnik dermatologii i venerologii, 1982, Issue:4

    Topics: Adult; Disease Susceptibility; Epilepsy; Female; Heart Defects, Congenital; Humans; Keloid; Male; Sy

1982
Dubowitz syndrome with keloidal lesions.
    Clinical and experimental dermatology, 1994, Volume: 19, Issue:5

    Topics: Abnormalities, Multiple; Child; Dermatitis, Atopic; Facial Expression; Growth Disorders; Humans; Kel

1994
A case of FG syndrome with gingival hyperplasia and keloids.
    Pediatric dermatology, 1995, Volume: 12, Issue:4

    Topics: Abnormalities, Multiple; Child; Gingival Hyperplasia; Humans; Keloid; Male; Syndrome

1995
Clinical genetics of familial keloids.
    Archives of dermatology, 2001, Volume: 137, Issue:11

    Topics: Adolescent; Adult; Age of Onset; Black People; Child; Diseases in Twins; Female; Genes, Dominant; Hu

2001
Epibulbar tumors in childhood.
    American journal of ophthalmology, 1975, Volume: 79, Issue:6

    Topics: Adolescent; Amyloidosis; Carcinoma, Squamous Cell; Child; Child, Preschool; Choristoma; Conjunctiva;

1975
[Keloidal blastomycosis (Lobo's disease)].
    Vestnik dermatologii i venerologii, 1988, Issue:11

    Topics: Adolescent; Biopsy; Blastomycosis; Combined Modality Therapy; Diagnosis, Differential; Humans; Keloi

1988
A note on the cultivation of the aetiological agent of Jorge Lôbo's disease in 199 T.C. medium containing phytohaemagglutinin. Preliminary report.
    Revista do Instituto de Medicina Tropical de Sao Paulo, 1974, Volume: 16, Issue:2

    Topics: Blastomyces; Blastomycosis; Culture Media; Humans; Keloid; Lectins; Syndrome

1974
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