Page last updated: 2024-10-30

khellin and Skin Diseases

khellin has been researched along with Skin Diseases in 113 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Skin Diseases: Diseases involving the DERMIS or EPIDERMIS.

Research Excerpts

ExcerptRelevanceReference
"When khellin was assayed with strain TA1537, mutation induction was not detectable; in the same strain, an equitoxic dose (52-56% level of survival) of TMP (used at a concentration 12-fold lower than khellin and with a UVA dose 83-fold lower than that used with khellin) yielded an increase in revertants/plate 3-fold above the spontaneous background."5.28Investigation of the mutagenic activity in Salmonella typhimurium of the furochromone khellin, proposed as a therapeutic agent for skin diseases. ( Bovalini, L; Coratza, G; Martelli, P; Riccio, ML, 1992)
"Keloids and hypertrophic scars are pathological cutaneous scars."2.82Role of Inflammasomes in Keloids and Hypertrophic Scars-Lessons Learned from Chronic Diabetic Wounds and Skin Fibrosis. ( Huang, C; Ogawa, R, 2022)
"Skin fibrosis is a common pathological process characterized by fibroblast proliferation and excessive deposition of extracellular matrix."2.55MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment. ( Chen, T; Lei, Y; Li, Y; Lyu, L; Zhang, J; Zuo, R, 2017)
"Keloids were thought to be prevalent in TS, but recent data suggest otherwise."2.42Turner's syndrome in dermatology. ( Glick, SA; Kim, KH; Lowenstein, EJ, 2004)
"Keloids and hypertrophic scars in children are effectively treated with silicone gel sheeting."2.39Skin disorders in black children. ( Laude, TA, 1996)
"Keloid is a heterogeneous disease featured by the excessive production of extracellular matrix."1.91UCHL1 aggravates skin fibrosis through an IGF-1-induced Akt/mTOR/HIF-1α pathway in keloid. ( Guo, C; Huang, J; Liang, L; Qiu, X; Tan, G; Wang, L; Xie, Y; Zheng, J, 2023)
"Cryosurgery, the most common treatment for keloids, causes skin traumas."1.72Ulvan-Based Nanofibrous Patches Enhance Wound Healing of Skin Trauma Resulting from Cryosurgical Treatment of Keloids. ( Ioannou, E; Karalis, V; Kikionis, S; Koromvoki, M; Kyritsi, A; Panagiotopoulos, A; Polichronaki, E; Rallis, M; Roussis, V; Stratigos, A; Tagka, A; Vitsos, A, 2022)
"Skin fibrosis is a hallmark of a wide array of dermatological diseases which can greatly impact the patients' quality of life."1.72Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies. ( Almudéver, P; Alonso-Carpio, M; Cortijo, J; Marín, S; Milara, J; Montero, P; Peiró, T; Ribera, P; Roger, I, 2022)
"Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal progression and post-surgical recurrence and histologically by the accumulation of collagen and fibroblast ingredients."1.46Keloid progression: a stiffness gap hypothesis. ( Du, Y; Huang, C; Liu, L; Ogawa, R; Wang, B; You, Z, 2017)
"The percentage of after-treatment keloids and hypertrophic scars observed was very low (~1%) especially upon the usage of lower parameters."1.38Highlights of thirty-year experience of CO2 laser use at the Florence (Italy) department of dermatology. ( Arunachalam, M; Bassi, A; Bonan, P; Bruscino, N; Campolmi, P; Cannarozzo, G; Lotti, T; Moretti, S; Troiano, M, 2012)
"Keloid is a fibrotic disease characterized by abnormal accumulation of extracellular matrix in the dermis."1.35Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid. ( Ikeda, M; Ishiko, T; Kubota, H; Kurokawa, M; Nagata, K; Naitoh, M; Nakamura, T; Suzuki, S; Utani, A; Yamawaki, S; Yoshikawa, K, 2009)
"Keloid was identified in 13 boys and 10 girls, accounting for 0."1.34Prevalence of childhood acne, ephelides, warts, atopic dermatitis, psoriasis, alopecia areata and keloid in Kaohsiung County, Taiwan: a community-based clinical survey. ( Chen, W; Cheng, YW; Lai, CS; Yang, YC, 2007)
"In the childhood population, atopic eczema and tinea capitis were the most frequent dermatoses, comprising 63% of diagnoses recorded."1.30A study of the spectrum of skin disease occurring in a black population in south-east London. ( Child, FJ; Du Vivier, AW; Fuller, LC; Higgins, EM, 1999)
"When khellin was assayed with strain TA1537, mutation induction was not detectable; in the same strain, an equitoxic dose (52-56% level of survival) of TMP (used at a concentration 12-fold lower than khellin and with a UVA dose 83-fold lower than that used with khellin) yielded an increase in revertants/plate 3-fold above the spontaneous background."1.28Investigation of the mutagenic activity in Salmonella typhimurium of the furochromone khellin, proposed as a therapeutic agent for skin diseases. ( Bovalini, L; Coratza, G; Martelli, P; Riccio, ML, 1992)
"Keloids are rapidly resolved with the use of flurandrenolide tape covered with positive-pressure chin-strap dressings."1.28The prevention and management of postdermabrasion complications. ( Fulton, JE, 1991)
"Significant scarring is a potential sequela of the second degree burns produced by argon or carbon dioxide laser surgery, and is particularly a risk for children."1.27Laser surgery for children. ( Brauner, GJ; Schliftman, A, 1987)
"In other situations, as in the treatment of keloids, physicians may wish to introduce drugs known to reduce scar formation into the biologic environment in which wound healing ensues."1.26Wound healing: a review. IV. Systemic medications affecting wound healing. ( Pollack, SV, 1982)
"Indications for radiotherapy of benign dermatoses have decreased markedly during the past decades."1.26[Roentgen therapy of dermatoses: indications and hazards]. ( Goldschmidt, H, 1978)

Research

Studies (113)

TimeframeStudies, this research(%)All Research%
pre-199058 (51.33)18.7374
1990's14 (12.39)18.2507
2000's16 (14.16)29.6817
2010's16 (14.16)24.3611
2020's9 (7.96)2.80

Authors

AuthorsStudies
Riccio, ML1
Coratza, G1
Bovalini, L2
Martelli, P2
Vedaldi, D1
Caffieri, S1
Dall'Acqua, F1
Andreassi, L1
Ud-Din, S1
Bayat, A2
Huang, C3
Ogawa, R4
Kikionis, S1
Koromvoki, M1
Tagka, A1
Polichronaki, E1
Stratigos, A1
Panagiotopoulos, A1
Kyritsi, A1
Karalis, V1
Vitsos, A1
Rallis, M1
Ioannou, E1
Roussis, V1
Peiró, T2
Alonso-Carpio, M2
Ribera, P2
Almudéver, P2
Roger, I2
Montero, P2
Marín, S2
Milara, J2
Cortijo, J2
Guo, C1
Liang, L1
Zheng, J1
Xie, Y1
Qiu, X1
Tan, G1
Huang, J1
Wang, L1
Santiago, S1
Brown, R1
Shao, K1
Hooper, J1
Perez, M1
Qin, G1
Sun, Y1
Guo, Y1
Song, Y1
Deng, CC1
Hu, YF1
Zhu, DH1
Cheng, Q1
Gu, JJ1
Feng, QL1
Zhang, LX1
Xu, YP1
Wang, D1
Rong, Z1
Yang, B1
Norouzi-Barough, L1
Li, Y1
Zhang, J1
Lei, Y1
Lyu, L1
Zuo, R1
Chen, T1
Coentro, JQ1
Pugliese, E1
Hanley, G1
Raghunath, M1
Zeugolis, DI1
El Amrani, F1
Hassam, B1
Ring, HC1
Mogensen, M1
Hussain, AA1
Steadman, N1
Banzhaf, C1
Themstrup, L1
Jemec, GB1
Guo, H1
Sheng, J1
Li, B1
Gao, XH1
Chen, HD1
Li, JH1
Elbendary, A1
Valdebran, M1
Parikh, K1
Elston, DM1
Liu, L1
You, Z1
Wang, B1
Du, Y1
Goyal, A1
Linskey, KR1
Kay, J1
Duncan, LM1
Nazarian, RM1
Nijhawan, RI1
Jacob, SE1
Woolery-Lloyd, H1
Cicchi, R1
Sestini, S1
De Giorgi, V1
Massi, D1
Lotti, T2
Pavone, FS1
Akaishi, S2
Hyakusoku, H2
Bernstein, EF1
Ikeda, M1
Naitoh, M1
Kubota, H1
Ishiko, T1
Yoshikawa, K1
Yamawaki, S1
Kurokawa, M1
Utani, A1
Nakamura, T1
Nagata, K1
Suzuki, S1
Shah, S1
Alster, TS1
Medyukhina, A1
Vogler, N1
Latka, I1
Kemper, S1
Böhm, M1
Dietzek, B1
Popp, J1
Lee, JY1
Youm, DJ1
Choi, CY1
Zhang, X1
Campolmi, P1
Bonan, P1
Cannarozzo, G1
Bassi, A1
Bruscino, N1
Arunachalam, M1
Troiano, M1
Moretti, S1
Zeitler, DM1
Herman, BS1
Snapp, HA1
Telischi, FF1
Angeli, SI1
Zimmerman, EE1
Crawford, P1
Taylor, SC1
Kelly, AP1
Dupree, NE1
Kimball, AB1
Lawrence, RC1
KEINING, E1
BRAUN-FALCO, O2
TUBIANA, R1
GILLMAN, T1
PENN, J1
BRONKS, D1
ROUX, M1
REYNAERS, H1
WOODMAN, EN1
MONTGOMERY, RM1
PORTNOY, M1
RAAB, W1
WADDINGTON, E1
BRAY, PT1
EVANS, AD1
RICHARDS, ID1
KOONIN, AJ1
SCHIMPF, A1
MEYER, J1
LEPINAY, B1
Berman, B3
Hengge, U1
Barton, S1
Lowenstein, EJ1
Kim, KH1
Glick, SA1
ALLINGTON, HV1
Golden, BA1
Zide, MF1
Waibel, KH1
Walsh, DS1
Drones, B1
Yang, YC1
Cheng, YW1
Lai, CS1
Chen, W1
Panizzon, RG1
Tio, TH1
Koźmińska-Kubarska, A1
Kirschner, RA1
Thomas, JR1
Doyle, JA1
Abergel, RP1
Meeker, CA1
Lam, TS1
Dwyer, RM1
Lesavoy, MA1
Uitto, J1
Redmond, WJ1
Baker, SR1
Pollack, SV1
Coffey, RJ1
Sahl, WJ1
Clever, H1
Kahle, B1
Zilow, E1
Springer, W1
Näher, H1
Ries, WR1
Speyer, MT1
Laude, TA1
Happak, W1
Kuzbari, R1
Flowers, A1
Freilinger, G1
Hashimoto, K1
Gasparro, FP1
Flores, J1
Burdick, A1
Jonusas, AM1
Pariser, RJ1
Child, FJ1
Fuller, LC1
Higgins, EM1
Du Vivier, AW1
Valencia, IC1
Falabella, AF1
Schachner, LA1
Güleç, AT1
Karaduman, A1
Seçkin, D1
Alexander, G1
Ebrahim, MK1
Verbov, J1
Goldschmidt, H2
Lukacs, S1
Benedetto, AV1
Bergfeld, WF1
Bodian, EL1
Solomon, LM1
Caputo, R1
Davis, J1
Evans, D1
Greenberg, M1
Hill, C1
Keuer, E1
Koya, D1
Morgan, N1
Pedvis-Leftick, A1
Wick, G1
Kraft, D1
Kokoschka, EM1
Timpl, R1
Kenney, JA1
Bowszyc, J1
Torre, D1
Wozniak, KD1
Braun, W1
Giannotti, B1
Pimpinelli, N1
Fulton, JE1
Duncan, MR1
Brauner, GJ1
Schliftman, A1
Eastern, JS1
Bailin, PL1
Ratz, JL1
Wheeland, RG1
Apfelberg, DB1
Smith, T1
Lash, H1
White, DN1
Maser, MR1
Young, EM1
Barr, RJ1
Morelli, JG1
Parrish, JA1
Fürnsinn, G1
Kimura, M1
Kjaer, M1
Walther, H1
Hansen, JE1
Studnitsin, AA1
Nikitina, MN1
Lashmanova, AP1
Nikitina, LV1
Sharapova, GIa1
Khamaganova, AV1
Kikuchi, I1
Horikawa, S1
Marsden, CW1
Rintala, AE1
Asko-Seljavaara, S1
Engel, MF1
Afanas'eva, OM1
Ratzer, MA1
Weitgasser, H1
Schmid, AH1
Depaoli, M1
Grasso, R1
Groel, JT1
Buccellato, G1
Hambrick, GW1
Carter, DM1

Reviews

21 reviews available for khellin and Skin Diseases

ArticleYear
Controlling Inflammation Pre-Emptively or at the Time of Cutaneous Injury Optimises Outcome of Skin Scarring.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Cicatrix, Hypertrophic; Humans; Inflammation; Keloid; Skin; Skin Diseases; Wound Healing

2022
Role of Inflammasomes in Keloids and Hypertrophic Scars-Lessons Learned from Chronic Diabetic Wounds and Skin Fibrosis.
    International journal of molecular sciences, 2022, Jun-19, Volume: 23, Issue:12

    Topics: Cicatrix, Hypertrophic; Diabetes Mellitus; Endothelial Cells; Fibrosis; Humans; Inflammasomes; Infla

2022
Validation strategies for identifying drug targets in dermal fibrotic disorders.
    Drug discovery today, 2021, Volume: 26, Issue:10

    Topics: Animals; Drug Development; Drug Discovery; Fibrosis; Humans; Keloid; Molecular Targeted Therapy; Ski

2021
MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment.
    Molecular diagnosis & therapy, 2017, Volume: 21, Issue:6

    Topics: Cicatrix, Hypertrophic; Fibrosis; Gene Expression Regulation; Humans; Keloid; MicroRNAs; Molecular T

2017
Current and upcoming therapies to modulate skin scarring and fibrosis.
    Advanced drug delivery reviews, 2019, Volume: 146

    Topics: Animals; Cicatrix, Hypertrophic; Fibrosis; Humans; Inflammation; Keloid; Skin Diseases

2019
Laser treatment of dark skin: an updated review.
    American journal of clinical dermatology, 2010, Dec-01, Volume: 11, Issue:6

    Topics: Adult; Cafe-au-Lait Spots; Child; Cicatrix, Hypertrophic; Hair Removal; Hemangioma; Humans; Keloid;

2010
Genome-wide association study of skin complex diseases.
    Journal of dermatological science, 2012, Volume: 66, Issue:2

    Topics: Alopecia; Carcinoma, Basal Cell; Dermatitis, Atopic; Female; Genetic Predisposition to Disease; Geno

2012
Successful management of viral infections and other dermatoses with imiquimod 5% cream.
    Acta dermato-venereologica. Supplementum, 2003, Issue:214

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aged, 80 and over; Aminoquinolines; Carcinoma in Si

2003
Turner's syndrome in dermatology.
    Journal of the American Academy of Dermatology, 2004, Volume: 50, Issue:5

    Topics: Female; Humans; Keloid; Lymphedema; Nevus; Skin Diseases; Skin Neoplasms; Turner Syndrome

2004
[Diagnosis of skin diseases in Negroes in Africa].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1984, Apr-23, Volume: 39, Issue:17

    Topics: Black People; Dermatomycoses; Diagnosis, Differential; Humans; Keloid; Leprosy; Skin Diseases; Skin

1984
The therapeutic uses of topical vitamin A acid.
    Journal of the American Academy of Dermatology, 1981, Volume: 4, Issue:5

    Topics: Acne Vulgaris; Animals; Callosities; Cocarcinogenesis; Fox-Fordyce Disease; Humans; Ichthyosis; Kelo

1981
Cutaneous scars: Part II.
    International journal of dermatology, 1994, Volume: 33, Issue:11

    Topics: Burns; Cell Transformation, Neoplastic; Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Skin Disea

1994
Cutaneous applications of lasers.
    Otolaryngologic clinics of North America, 1996, Volume: 29, Issue:6

    Topics: Aluminum Silicates; Argon; Carbon Dioxide; Cheilitis; Dermabrasion; Equipment Design; Humans; Keloid

1996
Skin disorders in black children.
    Current opinion in pediatrics, 1996, Volume: 8, Issue:4

    Topics: Black People; Child; Cicatrix; Hair; Humans; Hypertrophy; Keloid; Nevus, Pigmented; Skin Diseases; S

1996
Benign neoplasms of the skin.
    The Medical clinics of North America, 1998, Volume: 82, Issue:6

    Topics: Adult; Child; Diagnosis, Differential; Epidermal Cyst; Family Practice; Hemangioma; Histiocytoma, Be

1998
New developments in wound care for infants and children.
    Pediatric annals, 2001, Volume: 30, Issue:4

    Topics: Child; Drug Eruptions; Extravasation of Diagnostic and Therapeutic Materials; Humans; Infant; Infant

2001
Topical corticosteroids. Which drug and when?
    Drugs, 1992, Volume: 44, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Bites and Stings; Burns;

1992
Sclerosing dermatoses.
    Journal of cutaneous pathology, 1985, Volume: 12, Issue:5

    Topics: Diagnosis, Differential; Eosinophilia; Fasciitis; Humans; Keloid; Lichen Planus; Radiodermatitis; Sc

1985
Lasers in dermatology: a selective historical review.
    Photo-dermatology, 1985, Volume: 2, Issue:5

    Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatology; Humans; Keloid; Laser Therapy; Melanom

1985
[Side reaction following smallpox vaccination].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:4

    Topics: Encephalomyelitis, Acute Disseminated; Exanthema; gamma-Globulins; Humans; Indoles; Keloid; Neoplasm

1971
[Therapy of skin and venereal diseases. Review of the literature of 1967-68].
    Deutsches medizinisches Journal, 1969, Volume: 20, Issue:15

    Topics: Acne Vulgaris; Alopecia; Balanitis; Candidiasis; Dermatitis, Occupational; Dermatomycoses; Diaper Ra

1969

Trials

2 trials available for khellin and Skin Diseases

ArticleYear
Fluocinolone acetonide 0.2 per cent cream--a co-operative clinical trial.
    The British journal of dermatology, 1968, Volume: 80, Issue:9

    Topics: Clinical Trials as Topic; Epidermolysis Bullosa; Fluocinolone Acetonide; Folliculitis; Granuloma; Hu

1968
Dimethyl sulfoxide as a vehicle for corticosteroids. A comparison with the occlusive dressing technique.
    Archives of dermatology, 1968, Volume: 97, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatitis, Atopic; Dermatitis, Contact; Eczema; F

1968

Other Studies

90 other studies available for khellin and Skin Diseases

ArticleYear
Investigation of the mutagenic activity in Salmonella typhimurium of the furochromone khellin, proposed as a therapeutic agent for skin diseases.
    Mutation research, 1992, May-16, Volume: 279, Issue:2

    Topics: Khellin; Mutagenicity Tests; Mutagens; Photochemistry; Salmonella typhimurium; Skin Diseases

1992
Khellin, a naturally occurring furochromone, used for the photochemotherapy of skin diseases: mechanism of action.
    Il Farmaco; edizione scientifica, 1988, Volume: 43, Issue:4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Cross-Linking Reagents; Dialysis;

1988
Ulvan-Based Nanofibrous Patches Enhance Wound Healing of Skin Trauma Resulting from Cryosurgical Treatment of Keloids.
    Marine drugs, 2022, Aug-26, Volume: 20, Issue:9

    Topics: Antioxidants; Hemoglobins; Humans; Keloid; Nanofibers; Polyethylene Glycols; Polysaccharides; Skin D

2022
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Keloid; Mice; Quality of

2022
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Keloid; Mice; Quality of

2022
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Keloid; Mice; Quality of

2022
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Keloid; Mice; Quality of

2022
UCHL1 aggravates skin fibrosis through an IGF-1-induced Akt/mTOR/HIF-1α pathway in keloid.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:7

    Topics: Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblasts; Humans; Insulin-Like Growth Facto

2023
Modified Fitzpatrick Scale-Skin Color and Reactivity.
    Journal of drugs in dermatology : JDD, 2023, Jul-01, Volume: 22, Issue:7

    Topics: Cicatrix, Hypertrophic; Humans; Keloid; Skin; Skin Diseases; Skin Pigmentation

2023
PAX5 activates telomerase activity and proliferation in keloid fibroblasts by transcriptional regulation of SND1, thus promoting keloid growth in burn-injured skin.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2021, Volume: 70, Issue:4

    Topics: Adult; Animals; Burns; Cell Proliferation; Cell Survival; Cells, Cultured; Endonucleases; Female; Fi

2021
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases.
    Nature communications, 2021, 06-17, Volume: 12, Issue:1

    Topics: Cell Adhesion Molecules; Collagen; Extracellular Matrix; Fibroblasts; Gene Expression Regulation; Ge

2021
[Pseudo-keloid lesion revealing a cutaneous and pulmonary sarcoidosis].
    The Pan African medical journal, 2013, Volume: 14

    Topics: Humans; Keloid; Male; Middle Aged; Sarcoidosis; Sarcoidosis, Pulmonary; Skin Diseases

2013
Imaging of collagen deposition disorders using optical coherence tomography.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:5

    Topics: Adult; Cicatrix, Hypertrophic; Collagen; Humans; Keloid; Lichen Sclerosus et Atrophicus; Middle Aged

2015
Cutaneous dirt-adherent disease on the base of keloid.
    International journal of dermatology, 2015, Volume: 54, Issue:5

    Topics: Depression; Humans; Keloid; Male; Middle Aged; Skin Diseases

2015
Polarized Microscopy in Lesions With Altered Dermal Collagen.
    The American Journal of dermatopathology, 2016, Volume: 38, Issue:8

    Topics: Biomarkers, Tumor; Biopsy; Dermatofibrosarcoma; Diagnosis, Differential; Fibrillar Collagens; Histio

2016
Keloid progression: a stiffness gap hypothesis.
    International wound journal, 2017, Volume: 14, Issue:5

    Topics: Elasticity; Humans; Keloid; Skin Diseases; Wound Healing; Wounds and Injuries

2017
Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders: Implications for Targeted Inhibition.
    American journal of clinical pathology, 2016, Volume: 146, Issue:6

    Topics: beta Catenin; Cicatrix; Cicatrix, Hypertrophic; Glycogen Synthase Kinase 3 beta; Hedgehog Proteins;

2016
Skin of color education in dermatology residency programs: does residency training reflect the changing demographics of the United States?
    Journal of the American Academy of Dermatology, 2008, Volume: 59, Issue:4

    Topics: Curriculum; Dermatology; Humans; Internship and Residency; Keloid; Melanosis; Population Surveillanc

2008
Nonlinear laser imaging of skin lesions.
    Journal of biophotonics, 2008, Volume: 1, Issue:1

    Topics: Adult; Aged; Carcinoma, Basal Cell; Female; Humans; Keloid; Lasers; Male; Melanoma; Microscopy, Conf

2008
Differential and exclusive diagnosis of diseases that resemble keloids and hypertrophic scars.
    Annals of plastic surgery, 2009, Volume: 62, Issue:6

    Topics: Adenoma, Pleomorphic; Adult; Cicatrix, Hypertrophic; Cystadenoma; Diagnosis, Differential; Folliculi

2009
The pulsed-dye laser for treatment of cutaneous conditions.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2009, Volume: 144, Issue:5

    Topics: Cicatrix, Hypertrophic; Humans; Keloid; Lasers, Dye; Port-Wine Stain; Rosacea; Skin Diseases; Telang

2009
Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid.
    Biochemical and biophysical research communications, 2009, Dec-25, Volume: 390, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Chondroitin Sulfates; Elastic Tissue; Female; Humans; Keloid; Male;

2009
Automated classification of healthy and keloidal collagen patterns based on processing of SHG images of human skin.
    Journal of biophotonics, 2011, Volume: 4, Issue:9

    Topics: Algorithms; Collagen; Electron Microscope Tomography; Electronic Data Processing; Humans; Image Proc

2011
Conventional Epi-LASIK and lamellar epithelial debridement in myopic patients with dermatologic keloids.
    Korean journal of ophthalmology : KJO, 2011, Volume: 25, Issue:3

    Topics: Adult; Debridement; Eyeglasses; Female; Follow-Up Studies; Humans; Keloid; Keratomileusis, Laser In

2011
Highlights of thirty-year experience of CO2 laser use at the Florence (Italy) department of dermatology.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Cicatrix, Hypertrophic; Dermatologic Surgical Procedures; Dermatology; Female; Humans; Italy; Keloid

2012
Ethnic disparity in skin complications following bone-anchored hearing aid implantation.
    The Annals of otology, rhinology, and laryngology, 2012, Volume: 121, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone Conduction; Cicatrix, Hypertrophic; Cochlear Implan

2012
Are keloid and hypertrophic scar different forms of the same disorder? A fibroproliferative skin disorder hypothesis based on keloid findings.
    International wound journal, 2014, Volume: 11, Issue:5

    Topics: Adult; Cicatrix, Hypertrophic; Collagen; Diagnosis, Differential; Female; Fibrillar Collagens; Fibro

2014
Cutaneous cryosurgery.
    American family physician, 2012, Dec-15, Volume: 86, Issue:12

    Topics: Condylomata Acuminata; Cryosurgery; Histiocytoma, Benign Fibrous; Humans; Keloid; Keratosis, Actinic

2012
Health disparities in arthritis and musculoskeletal and skin diseases-the dermatology session: National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, Maryland, December 15-16, 2000.
    Journal of the American Academy of Dermatology, 2002, Volume: 47, Issue:5

    Topics: Acne Vulgaris; Black People; Health Surveys; Humans; Keloid; Minority Groups; Racial Groups; Researc

2002
[Comparison of the keloid, scleredema and myxedema].
    Dermatologische Wochenschrift, 1952, Volume: 126, Issue:27

    Topics: Humans; Keloid; Myxedema; Scleredema Adultorum; Skin Diseases

1952
[Medico-surgical problems in dermatology; report of some observations made in U.S.A. on the treatment of keloid, angioma, radio-dermatitis, naevus planus, naevus carcinoma and epithelioma of the face].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1953, May-20, Volume: 29, Issue:33

    Topics: Dermatitis; Dermatology; Hemangioma; Humans; Keloid; Nevus; Nevus, Pigmented; Skin Diseases; Skin Ne

1953
Reactions of healing wounds and granulation tissue in man to auto-Thiersch, autodermal, and homodermal grafts: with an analysis of the implications of the phenomena encountered for an understanding of the behaviour of grafted tissue and the genesis of sca
    British journal of plastic surgery, 1953, Volume: 6, Issue:3

    Topics: Cicatrix; Granulation Tissue; Humans; Keloid; Male; Skin Diseases; Skin Transplantation; Transplants

1953
[Keloids scattered over the thorax following a postpartum eruption of undetermined nature].
    Archives belges de dermatologie et de syphiligraphie, 1953, Volume: 9, Issue:1

    Topics: Exanthema; Female; Fibroma; Humans; Keloid; Postpartum Period; Skin Diseases; Thorax

1953
THE TREATMENT OF SKIN CONDITIONS IN THE RADIOTHERAPY DEPARTMENT.
    Radiography, 1963, Volume: 29

    Topics: Acne Vulgaris; Geriatrics; Hair Removal; Humans; Keloid; Keratosis; Neoplasms; Pruritus; Radiotherap

1963
TRIAMCINOLONE ACETONIDE INJECTED SUBLESIONALLY IN THE TREATMENT OF DERMATOSES.
    Journal of the American Geriatrics Society, 1963, Volume: 11

    Topics: Asian People; Black People; Dermatitis; Dermatology; Eczema; Geriatrics; Granuloma; Humans; Keloid;

1963
[EXPERIENCES WITH INTRALESIONAL CORTICOSTEROID TREATMENT OF SEVERAL SKIN DISEASES].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1964, Jan-01, Volume: 36

    Topics: Adrenal Cortex Hormones; Alopecia Areata; Cheilitis; Eczema; Granuloma; Humans; Injections; Keloid;

1964
CUTANEOUS COMPLICATIONS OF MASS VACCINATION AGAINST SMALLPOX IN SOUTH WALES 1962.
    Transactions of the St. John's Hospital Dermatological Society, 1964, Volume: 50

    Topics: Adolescent; Child; Communicable Diseases; Female; Fetal Diseases; Hematologic Diseases; Humans; Infa

1964
THE AETIOLOGY OF KELOIDS: A REVIEW OF THE LITERATURE AND A NEW HYPOTHESIS.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1964, Nov-21, Volume: 38

    Topics: Acromegaly; Black People; Cicatrix; Drug Therapy; Foreign Bodies; Humans; Hydrocortisone; Hyperthyro

1964
[PRIMARY BLASTOMATOUS RETICULOSIS OF THE SKIN SIMULATING MORPHEA)].
    Archiv fur klinische und experimentelle Dermatologie, 1965, Apr-26, Volume: 222

    Topics: Humans; Keloid; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma; Scalp; S

1965
[Physiotherapy. V. Physiotherapy of cicatrices, keloids and dermohypodermic scleroses].
    Concours medical, 1962, Jan-13, Volume: 84

    Topics: Cicatrix; Humans; Keloid; Physical Therapy Modalities; Sclerosis; Skin Diseases

1962
Liquid nitrogen in the treatment of skin diseases.
    California medicine, 1950, Volume: 72, Issue:3

    Topics: Cicatrix; Dermatitis, Contact; Freezing; Hemangioma; Humans; Keloid; Keratosis; Leukoplakia; Nitroge

1950
Cutaneous cysts of the head and neck.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2005, Volume: 63, Issue:11

    Topics: Adult; Dermoid Cyst; Epidermal Cyst; Female; Head and Neck Neoplasms; Hidrocystoma; Humans; Keloid;

2005
Smallpox vaccination site reactions: two cases of exaggerated scarring and a brief review.
    International journal of dermatology, 2006, Volume: 45, Issue:6

    Topics: Adult; Cicatrix; Female; Humans; Keloid; Male; Skin Diseases; Smallpox Vaccine

2006
Benign neoplasms/hyperplasia.
    Dermatology nursing, 2006, Volume: 18, Issue:4

    Topics: Bony Callus; Callosities; Cysts; Fibroma; Histiocytoma, Benign Fibrous; Humans; Hyperplasia; Keloid;

2006
Prevalence of childhood acne, ephelides, warts, atopic dermatitis, psoriasis, alopecia areata and keloid in Kaohsiung County, Taiwan: a community-based clinical survey.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:5

    Topics: Acne Vulgaris; Alopecia Areata; Chi-Square Distribution; Child; Cross-Sectional Studies; Dermatitis,

2007
[Dermatologic radiotherapy].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2007, Volume: 58, Issue:8

    Topics: Eczema; Humans; Keloid; Lymphoma, B-Cell; Lymphoma, T-Cell, Cutaneous; Palliative Care; Precancerous

2007
Strophulus in Indonesia.
    Dermatologica, 1967, Volume: 135, Issue:1

    Topics: Adolescent; Child; Dermatologic Agents; Female; Humans; Indonesia; Insect Bites and Stings; Insect R

1967
Cutaneous plastic surgery with the CO2 laser.
    The Surgical clinics of North America, 1984, Volume: 64, Issue:5

    Topics: Biopsy; Carbon Dioxide; Cicatrix; Female; Hemangioma; Humans; Keloid; Keratosis; Laser Therapy; Lent

1984
Control of connective tissue metabolism by lasers: recent developments and future prospects.
    Journal of the American Academy of Dermatology, 1984, Volume: 11, Issue:6

    Topics: Animals; Cells, Cultured; Collagen; Connective Tissue; Fibroblasts; Humans; Keloid; Laser Therapy; S

1984
Keloidal calcification.
    Archives of dermatology, 1983, Volume: 119, Issue:3

    Topics: Aged; Calcinosis; Female; Humans; Keloid; Skin Diseases

1983
Wound healing: a review. IV. Systemic medications affecting wound healing.
    The Journal of dermatologic surgery and oncology, 1982, Volume: 8, Issue:8

    Topics: Adrenal Cortex Hormones; Aminopropionitrile; Animals; Anti-Inflammatory Agents; Anticoagulants; Anti

1982
In-office care of postoperative incisions.
    Medical times, 1981, Volume: 109, Issue:9

    Topics: Ambulatory Care; Fistula; Hernia; Humans; Intestinal Fistula; Keloid; Postoperative Care; Postoperat

1981
[Cicatricial keloids after Waterhouse-Friderichsen syndrome].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1994, Volume: 45, Issue:2

    Topics: Cicatrix, Hypertrophic; Follow-Up Studies; Hemorrhage; Humans; Infant; Keloid; Male; Necrosis; Skin;

1994
[Utilization potential of the CO2-laser in dermal changes].
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 1996, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Female; Follow-Up Studies; H

1996
Linear focal elastosis: Keloidal repair of striae distensae.
    Journal of the American Academy of Dermatology, 1998, Volume: 39, Issue:2 Pt 2

    Topics: Adult; Connective Tissue Diseases; Elastic Tissue; Humans; Keloid; Male; Skin Diseases

1998
p53 in dermatology.
    Archives of dermatology, 1998, Volume: 134, Issue:8

    Topics: Animals; Carcinoma, Squamous Cell; DNA Damage; DNA Repair; Extracellular Matrix; Fibroblasts; Furoco

1998
The effectiveness of a new method for assessing induration.
    Journal of the American Academy of Dermatology, 1998, Volume: 39, Issue:6

    Topics: Female; Hardness; Humans; Keloid; Male; Predictive Value of Tests; Skin Diseases

1998
A study of the spectrum of skin disease occurring in a black population in south-east London.
    The British journal of dermatology, 1999, Volume: 141, Issue:3

    Topics: Acne Vulgaris; Acrodermatitis; Adult; Black or African American; Black People; Child; Cohort Studies

1999
Noonan syndrome: a case with recurrent keloid formation.
    Cutis, 2001, Volume: 67, Issue:4

    Topics: Child; Humans; Keloid; Male; Noonan Syndrome; Recurrence; Skin Diseases

2001
Spontaneous bleeding following steroid injection and silicone-gel sheeting in a keloid scar.
    British journal of plastic surgery, 2002, Volume: 55, Issue:2

    Topics: Child; Glucocorticoids; Hemorrhage; Humans; Keloid; Male; Silicone Gels; Skin Diseases; Triamcinolon

2002
The place of intralesional steroid therapy in dermatology.
    The British journal of dermatology, 1976, Volume: 94 suppl 12

    Topics: Acne Vulgaris; Adult; Aged; Alopecia Areata; Humans; Injections, Jet; Keloid; Lupus Erythematosus, S

1976
[Roentgen therapy of dermatoses: indications and hazards].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1978, Volume: 29, Issue:5

    Topics: Acne Vulgaris; Eczema; Foot Dermatoses; Humans; Keloid; Lichen Planus; Lymphocytosis; Neoplasms, Rad

1978
Radiotherapy of benign dermatoses: indications, practice, and results.
    The Journal of dermatologic surgery and oncology, 1978, Volume: 4, Issue:8

    Topics: Acne Vulgaris; Bacterial Infections; Dupuytren Contracture; Eczema; Female; Hemangioma; Herpes Simpl

1978
Audiofrequency electrotherapy in skin diseases.
    Chinese medical journal, 1977, Volume: 3, Issue:6

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatitis, Contact; Electric Stimulation Therapy;

1977
Acanthoma fissuratum. Histopathology and review of the literature.
    Cutis, 1979, Volume: 24, Issue:2

    Topics: Adolescent; Connective Tissue; Diagnosis, Differential; Ear; Granuloma; Humans; Keloid; Male; Skin D

1979
Electrosurgery by bipolar modalities.
    The Journal of dermatologic surgery and oncology, 1978, Volume: 4, Issue:3

    Topics: Electrosurgery; Granuloma; Humans; Keloid; Pacemaker, Artificial; Rhinophyma; Skin Diseases; Skin Ne

1978
Miscellaneous dermatoses.
    Major problems in clinical pediatrics, 1978, Volume: 19

    Topics: Acanthosis Nigricans; Adolescent; Athletic Injuries; Dermatomycoses; Female; Granuloma; Humans; Icht

1978
The diagnostic application of specific anti-procollagen sera. I. Analysis of skin biopsies.
    Clinical immunology and immunopathology, 1976, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Aged; Humans; Immune Sera; Keloid; Lichen Planus; Lupus Erythematosus, Discoid; L

1976
Skin problems of blacks.
    JAMA, 1976, Jul-19, Volume: 236, Issue:3

    Topics: Acne Keloid; Alopecia; Black People; Female; Hair Removal; Humans; Keloid; Male; Pigmentation Disord

1976
[Treatment of keloids and some skin diseases with topical injections of triamcinolone].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1976, Jun-28, Volume: 31, Issue:26

    Topics: Administration, Topical; Adolescent; Adult; Child; Female; Humans; Injections; Keloid; Male; Middle

1976
Cosmetic aspects of cryosurgery.
    Cutis, 1976, Volume: 17, Issue:3

    Topics: Adenoma; Cryosurgery; Fibroma; Humans; Keloid; Keratosis; Nevus, Pigmented; Sebaceous Gland Neoplasm

1976
[Treatment with hyaluronidase in dermatology].
    Zeitschrift fur arztliche Fortbildung, 1975, Nov-01, Volume: 69, Issue:21

    Topics: Humans; Hyaluronoglucosaminidase; Keloid; Male; Penile Induration; Scleroderma, Localized; Scleroder

1975
The prevention and management of postdermabrasion complications.
    The Journal of dermatologic surgery and oncology, 1991, Volume: 17, Issue:5

    Topics: Dermabrasion; Female; Humans; Keloid; Pigmentation Disorders; Skin Diseases

1991
Pentoxifylline inhibits the proliferation of human fibroblasts derived from keloid, scleroderma and morphoea skin and their production of collagen, glycosaminoglycans and fibronectin.
    The British journal of dermatology, 1990, Volume: 123, Issue:3

    Topics: Cell Division; Collagen; Depression, Chemical; Fibroblasts; Fibronectins; Glycosaminoglycans; Humans

1990
Laser surgery for children.
    The Journal of dermatologic surgery and oncology, 1987, Volume: 13, Issue:2

    Topics: Acne Vulgaris; Child; Cicatrix; Hemangioma; Humans; Keloid; Laser Therapy; Pigmentation Disorders; S

1987
Lasers in private dermatologic practice.
    Cutis, 1986, Volume: 37, Issue:4

    Topics: Argon; Carbon Dioxide; Hematoma; Herpes Simplex; Humans; Keloid; Laser Therapy; Lasers; Lymphadeniti

1986
Laser therapy of the skin. A review of principles and applications.
    Dermatologic clinics, 1987, Volume: 5, Issue:2

    Topics: Hemangioma; Humans; Keloid; Laser Therapy; Nevus, Pigmented; Photochemotherapy; Skin Diseases; Skin

1987
Preliminary report on use of the neodymium-YAG laser in plastic surgery.
    Lasers in surgery and medicine, 1987, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Epistaxis; Female; Granuloma; Hemangioma; Humans;

1987
[The use of lasers in medicine with special reference to dermatology].
    Wiener klinische Wochenschrift, 1985, Jun-21, Volume: 97, Issue:13

    Topics: Bowen's Disease; Carcinoma, Basal Cell; Condylomata Acuminata; Eye Protective Devices; Humans; Keloi

1985
Congenital skin defects.
    Acta dermato-venereologica, 1968, Volume: 48, Issue:6

    Topics: Anti-Infective Agents, Local; Birth Injuries; Dermatitis, Seborrheic; Diagnosis, Differential; Femal

1968
Cryosurgical therapy of benign lesions of the skin and mucous membranes.
    International surgery, 1971, Volume: 56, Issue:6

    Topics: Adult; Aged; Cryosurgery; Cysts; Dermatitis, Seborrheic; Epistaxis; Gingival Neoplasms; Hemangioma;

1971
[Treatment of dermatoses in children with synalar-forte, synalar-gel and metosyn].
    Vestnik dermatologii i venerologii, 1974, Volume: 0, Issue:8

    Topics: Acetates; Adolescent; Child; Child, Preschool; Drug Evaluation; Eczema; Fluocinolone Acetonide; Gran

1974
[Treatment of some dermatoses by the intradermal injections of a 10 percent solution of quingamine].
    Sovetskaia meditsina, 1973, Volume: 36, Issue:6

    Topics: Adult; Chloroquine; Chronic Disease; Female; Humans; Injections, Intradermal; Keloid; Lupus Erythema

1973
Perilymphatic atrophy of the skin. A side effect of topical corticosteroid injection therapy.
    Archives of dermatology, 1974, Volume: 109, Issue:4

    Topics: Atrophy; Child; Female; Humans; Keloid; Lymphatic System; Skin Diseases; Triamcinolone Acetonide

1974
Reconstruction of midline skin defects of the nose.
    Scandinavian journal of plastic and reconstructive surgery, 1969, Volume: 3, Issue:2

    Topics: Adult; Aged; Carcinoma, Basal Cell; Cicatrix; Facial Dermatoses; Female; Hodgkin Disease; Humans; Ke

1969
Indications and contraindications for the use of DMSO in clinical dermatology.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Amyloidosis; Animals; Anura; Dimethyl Sulfoxide; Dogs; Eczema; Humans; Keloid; Keratosis; Lichen Pla

1967
[Our experience in the treatment of certain dermatoses with ultra-soft roentgen rays (Bucky rays)].
    Vestnik dermatologii i venerologii, 1969, Volume: 43, Issue:11

    Topics: Adolescent; Adult; Cheilitis; Eczema; Female; Humans; Keloid; Lichen Planus; Male; Middle Aged; Neur

1969
A clinical trial of flurandrenolone tape.
    The British journal of clinical practice, 1970, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Flurandrenolone; Humans; Keloid; Male; Mid

1970
[Dermatological experience with dimethyl sulfoxide (DMSO)].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1967, Sep-15, Volume: 42, Issue:18

    Topics: Dimethyl Sulfoxide; Dupuytren Contracture; Female; Fibroma; Granuloma; Herpes Zoster; Humans; Keloid

1967
[Local treatment of skin diseases with Volon A tincture].
    Medizinische Klinik, 1967, Nov-17, Volume: 62, Issue:46

    Topics: Alopecia Areata; Benzalkonium Compounds; Dermatologic Agents; Eczema; Humans; Keloid; Lichen Planus;

1967
[Erythemato-pigmentary reaction with hypertrichosis in the site of injection of hematoporphyrin].
    Minerva dermatologica, 1967, Volume: 42, Issue:4

    Topics: Adult; Female; Hematoporphyrins; Humans; Hypertrichosis; Injections, Intramuscular; Keloid; Pigmenta

1967
[Selective action of paramethyl-isopropyl-phenol (thymol) on tissues in intense anaplastic-dysplastic proliferative activity].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Sep-15, Volume: 41, Issue:17

    Topics: Adenocarcinoma; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Division; Condylomata Acuminat

1965
Pachydermoperiostosis. Touraine-Solente-Golé syndrome.
    Archives of dermatology, 1966, Volume: 94, Issue:5

    Topics: Adult; Bone Diseases; Diagnosis, Differential; Female; Humans; Keloid; Keratosis; Male; Middle Aged;

1966