khellin has been researched along with Skin Aging in 10 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
Skin Aging: The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No reports of keloid formation, hypertrophic scarring, hypo- or hyperpigmentation, or other clinically significant adverse events were recorded." | 2.74 | Six-month safety results of calcium hydroxylapatite for treatment of nasolabial folds in Fitzpatrick skin types IV to VI. ( Boyd, CM; Grimes, PE; Marmur, ES; Porter, JP; Taylor, SC; Yoo, JY, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, JL | 1 |
| Scuderi, N | 1 |
| Connolly, D | 1 |
| Schilling, L | 1 |
| Saedi, N | 1 |
| Shook, BA | 1 |
| Wasko, RR | 1 |
| Rivera-Gonzalez, GC | 1 |
| Salazar-Gatzimas, E | 1 |
| López-Giráldez, F | 1 |
| Dash, BC | 1 |
| Muñoz-Rojas, AR | 1 |
| Aultman, KD | 1 |
| Zwick, RK | 1 |
| Lei, V | 1 |
| Arbiser, JL | 1 |
| Miller-Jensen, K | 1 |
| Clark, DA | 1 |
| Hsia, HC | 1 |
| Horsley, V | 1 |
| Ibrahim, O | 1 |
| Keller, EC | 1 |
| Arndt, KA | 1 |
| Marmur, ES | 1 |
| Taylor, SC | 1 |
| Grimes, PE | 1 |
| Boyd, CM | 1 |
| Porter, JP | 1 |
| Yoo, JY | 1 |
| Brissett, AE | 1 |
| Naylor, MC | 1 |
| Rossi, A | 1 |
| Alexis, AF | 1 |
| Raulin, C | 1 |
| Greve, B | 1 |
| Warncke, SH | 1 |
| Gundogan, C | 1 |
| Galus, R | 1 |
| Antiszko, M | 1 |
| Włodarski, P | 1 |
| Odunze, M | 1 |
| Cohn, A | 1 |
| Few, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Post-Marketing Study of Radiesse® Injectable Dermal Filler for the Treatment of Nasolabial Folds in Persons of Color[NCT01012388] | Phase 4 | 100 participants (Actual) | Interventional | 2007-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Skin type IV - Burns minimally, tans moderately and easily, Skin type V - Rarely burns, tans profusely; Skin type VI - Never burns, tans profusely (NCT01012388)
Timeframe: 3 months
| Intervention | Participants (Number) |
|---|---|
| Radiesse Injectable Dermal Filler | 0 |
Skin type IV - Burns minimally, tans moderately and easily, Skin type V - Rarely burns, tans profusely; Skin type VI - Never burns, tans profusely (NCT01012388)
Timeframe: 6 months
| Intervention | participants (Number) |
|---|---|
| Radiesse Injectable Dermal Filler | 0 |
4 reviews available for khellin and Skin Aging
| Article | Year |
|---|---|
Safety and Patient Satisfaction of AbobotulinumtoxinA for Aesthetic Use: A Systematic Review.
Topics: Antibodies, Neutralizing; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Clinical Trials as Topic | 2017 |
Advances in fractional technology for skin rejuvenation, skin tightening, drug delivery, and treating scars and skin defects.
Topics: Administration, Cutaneous; Cicatrix; Cicatrix, Hypertrophic; Cosmetic Techniques; Drug Delivery Syst | 2017 |
Update on botulinum neurotoxin use in aesthetic dermatology.
Topics: Administration, Topical; Botulinum Toxins, Type A; Cosmetic Techniques; Hot Flashes; Humans; Injecti | 2014 |
[Clinical applications of hyaluronic acid].
Topics: Adult; Child; Cicatrix; Humans; Hyaluronic Acid; Keloid; Osteoarthritis; Secondary Prevention; Skin | 2006 |
1 trial available for khellin and Skin Aging
| Article | Year |
|---|---|
Six-month safety results of calcium hydroxylapatite for treatment of nasolabial folds in Fitzpatrick skin types IV to VI.
Topics: Adult; Aged; Biocompatible Materials; Cosmetic Techniques; Dermatologic Agents; Durapatite; Female; | 2009 |
5 other studies available for khellin and Skin Aging
| Article | Year |
|---|---|
Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair.
Topics: Adipocytes; Animals; Cell Proliferation; Extracellular Matrix; Fibrosis; Integrin beta1; Keloid; Lec | 2018 |
The aging African-American face.
Topics: Alopecia; Black or African American; Blepharoplasty; Botulinum Toxins, Type A; Chemexfoliation; Derm | 2010 |
Cosmetic procedures in skin of color.
Topics: Chemexfoliation; Cosmetic Techniques; Culture; Esthetics; Hair Removal; Hirsutism; Humans; Keloid; L | 2011 |
[Excimer laser. Treatment of iatrogenic hypopigmentation following skin resurfacing].
Topics: Aged; Cosmetic Techniques; Female; Follow-Up Studies; Humans; Hypopigmentation; Iatrogenic Disease; | 2004 |
Restylane and people of color.
Topics: Cicatrix, Hypertrophic; Cosmetic Techniques; Female; Genetic Predisposition to Disease; Humans; Hyal | 2007 |