khellin has been researched along with Pain in 55 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Keloids are abnormal overgrowth of collagen fibers, and the first-line treatment includes intralesional injection of triamcinolone acetonide (TA), which is associated with pain." | 9.24 | A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial. ( Burusapat, C; Usanakornkul, A, 2017) |
| "This prospective study evaluates an argon gas-based system for the treatment of keloids in a patient population including all Fitzpatrick skin types with a 1-year follow-up." | 9.19 | A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy. ( Bulstra, AE; Niessen, FB; van Leeuwen, MC; van Leeuwen, PA, 2014) |
| "When comparing with topical lidocaine/prilocaine (EMLA) cream, a 1:1 mixture of 1% lidocaine and epinephrine significantly alleviated pain during and after the corticosteroid injection." | 8.31 | Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study. ( Park, TH, 2023) |
| "The histopathological changes and immunohistochemical studies occurring in keloids in vivo after treatment by intralesional (IL) verapamil are not yet assessed." | 8.02 | Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study. ( Abou-Taleb, DAE; Badary, DM, 2021) |
| "Because intralesional injection of triamcinolone acetonide (TA), a widely used for the treatment of keloid, is painful, many patients discontinue treatment." | 7.75 | Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid. ( Hyakusoku, H; Murakami, M; Tosa, M, 2009) |
| "We studied the long-term outcome of injection of triamcinolone acetonide into keloid scars in Asian patients." | 7.73 | Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients. ( Hata, Y; Igawa, HH; Ito, O; Muneuchi, G; Onodera, M; Suzuki, S, 2006) |
| "The feasibility of iontophoretic transdermal delivery of tranilast (N-(3,4-dimethoxycinnamoyl) anthranilic acid) for the treatment of keloid and hypertrophic scars was evaluated in hairless rats and humans." | 7.69 | Treatment of keloid and hypertrophic scars by iontophoretic transdermal delivery of tranilast. ( Ikuta, Y; Murakami, T; Shigeki, S; Yata, N, 1997) |
| "Hyperpigmentation was the most irritating side effect of 5-FU that occurred." | 5.72 | Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis. ( Attwa, E; Essam, R; Khater, MH; Selim, HM, 2022) |
| "Keloids are abnormal overgrowth of collagen fibers, and the first-line treatment includes intralesional injection of triamcinolone acetonide (TA), which is associated with pain." | 5.24 | A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial. ( Burusapat, C; Usanakornkul, A, 2017) |
| "This prospective study evaluates an argon gas-based system for the treatment of keloids in a patient population including all Fitzpatrick skin types with a 1-year follow-up." | 5.19 | A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy. ( Bulstra, AE; Niessen, FB; van Leeuwen, MC; van Leeuwen, PA, 2014) |
| "We investigated treatment outcomes of intralesional triamcinolone acetonide (IL TAC) compared with combination IL TAC and cryotherapy, including changes in pruritus, pain, and keloid size." | 4.31 | Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids. ( Banner, L; Cohen, AJ; Gleason, L; Lazarevic, B; Malkani, K; Nikbakht, N; Talasila, S; Uitto, J, 2023) |
| "When comparing with topical lidocaine/prilocaine (EMLA) cream, a 1:1 mixture of 1% lidocaine and epinephrine significantly alleviated pain during and after the corticosteroid injection." | 4.31 | Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study. ( Park, TH, 2023) |
| "The histopathological changes and immunohistochemical studies occurring in keloids in vivo after treatment by intralesional (IL) verapamil are not yet assessed." | 4.02 | Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study. ( Abou-Taleb, DAE; Badary, DM, 2021) |
| "After intralesional injection of triamcinolone acetonide, most of the hypertrophic scars and keloids improved in color, thickness, softness, and vascular distribution." | 3.91 | Comparative efficacy of intralesional triamcinolone acetonide injection during early and static stage of pathological scarring. ( Ao, M; Fu, Q; Huang, L; Song, H; Tan, J, 2019) |
| "The authors recruited 40 patients with 58 keloids who were scheduled to undergo intralesional triamcinolone acetonide (TA) injections." | 3.85 | Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment. ( Chung, WS; Hong, JY; Kim, BJ; Kim, MN; Lee, Y; Park, KY, 2017) |
| "Because intralesional injection of triamcinolone acetonide (TA), a widely used for the treatment of keloid, is painful, many patients discontinue treatment." | 3.75 | Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid. ( Hyakusoku, H; Murakami, M; Tosa, M, 2009) |
| "We studied the long-term outcome of injection of triamcinolone acetonide into keloid scars in Asian patients." | 3.73 | Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients. ( Hata, Y; Igawa, HH; Ito, O; Muneuchi, G; Onodera, M; Suzuki, S, 2006) |
| "Intralesional injection of triamcinolone acetonide (TA) for the treatment of keloid is painful, and lidocaine-mixed preparations are much the same." | 3.70 | Pain-free intralesional injection of triamcinolone for the treatment of keloid. ( Ono, N, 1999) |
| "The feasibility of iontophoretic transdermal delivery of tranilast (N-(3,4-dimethoxycinnamoyl) anthranilic acid) for the treatment of keloid and hypertrophic scars was evaluated in hairless rats and humans." | 3.69 | Treatment of keloid and hypertrophic scars by iontophoretic transdermal delivery of tranilast. ( Ikuta, Y; Murakami, T; Shigeki, S; Yata, N, 1997) |
| "Cryoanesthesia is ideally intended to cool only the epidermis during treatment and has advantage which did not require application time." | 3.30 | Cold anesthesia for pain reduction during intralesional steroid injection for nodulocystic acne. ( Kim, GH; Koh, YG; Park, KY; Park, SJ; Rho, NK; Shin, SH, 2023) |
| "Keloids are chronic progressive dermal pseudo-tumors that can grow considerably in volume and surface area but do not invade other tissues." | 3.01 | Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis. ( Charvet, E; Delaleu, J; Petit, A, 2023) |
| "First-line treatment of formed keloids involves topical or intralesional steroids." | 2.90 | Intralesional triamcinolone alone or in combination with botulinium toxin A is ineffective for the treatment of formed keloid scar: A double blind controlled pilot study. ( Bakhshaeekia, A; Feily, A; Gianfaldoni, S; Hadibarhaghtalab, M; Lange, CS; Lotti, T; Matta, J; Pazyar, N; Ramirez-Fort, MK; Ramirez-Pacheco, LA; Rasaii, S; Seifi, V; Sohrabian, N, 2019) |
| "Keloids are a burden for patients due to physical, aesthetic and social consequences." | 2.87 | Intralesional cryotherapy versus excision with corticosteroid injections or brachytherapy for keloid treatment: Randomised controlled trials. ( Bijlard, E; Hovius, SER; Mureau, MAM; Niessen, FB; Timman, R; Verduijn, GM, 2018) |
| "Different approaches are used aiming to improve these scars, including intralesional corticosteroids, surgery and more recently, laser therapy." | 2.82 | Laser therapy for treating hypertrophic and keloid scars. ( da Silva, CA; da Silva, EM; Kuczynski, U; Leszczynski, R; Pinto, ACPN, 2022) |
| "Recurrence was seen in seven keloids (24 percent) and hypopigmentation recovered in 69 percent of all keloid scars within 12 months." | 2.80 | Intralesional cryotherapy for treatment of keloid scars: a prospective study. ( Bulstra, AJ; Galindo-Garre, F; Molier, J; Niessen, FB; van der Wal, MBA; van Leeuwen, MCE; van Leeuwen, PAM; van Zuijlen, PPM, 2015) |
| "The symptom of pruritus is frequently overlooked by dermatologists, and treatments are often primarily focused on the gross appearance of the scar." | 2.72 | Pruritus in Keloid Scars: Mechanisms and Treatments. ( Hawash, AA; Ingrasci, G; Nouri, K; Yosipovitch, G, 2021) |
| "Keloid is characterized by tumor-like invasive growth, high incidence, and low remission rate." | 2.58 | [Advances in the research of drug intralesional injection therapy in keloid]. ( Guo, QG; Yao, M, 2018) |
| "The minimal treatment-related pain and high patient satisfaction makes it a promising treatment for patients with needle-phobia and/or severe pain during needle injections." | 1.91 | Needle-free electronically controlled jet injection with corticosteroids in recalcitrant keloid scars: a retrospective study and patient survey. ( Bik, L; Elmzoon, I; Prens, EP; van Doorn, MBA; Wolkerstorfer, A, 2023) |
| "Keloid-associated pruritus is a common manifestation and has negative impacts on quality of life." | 1.91 | Pruritus in keloid scars: mechanisms and treatments. ( Biazus Soares, G; Mahmoud, O; Yosipovitch, G, 2023) |
| "Improvement of skin parameters (scar elasticity, thickness, regularity, color) was also noticed." | 1.91 | Effectiveness of various methods of manual scar therapy. ( Garncarczyk, A; Lubczyńska, A; Wcisło-Dziadecka, D, 2023) |
| "Keloids are the result of abnormal wound healing, and they differ from the normal skin of the patient in the level of blood perfusion and the degrees of inflammation, hypoxia, regeneration of vessels, and expression of sensory receptors." | 1.72 | Relative perfusion index: An objective, quantitative and noninvasive method for evaluating the severity of keloids. ( Li, S; Long, X; Wang, X; Zhang, M, 2022) |
| "Hyperpigmentation was the most irritating side effect of 5-FU that occurred." | 1.72 | Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis. ( Attwa, E; Essam, R; Khater, MH; Selim, HM, 2022) |
| "Keloids are disfiguring pathological scars that could cause pain and pruritus." | 1.62 | Enhanced Drug Permeation into Human Keloid Tissues by Sonophoresis-Assisted Microneedling. ( Hu, T; Liu, W; Ning, X; Xia, L; Xu, C; Yang, Y, 2021) |
| "The keloids were most commonly located on the trunk, and seven patients had intralesional steroid injections prior to presentation with persistence of symptoms." | 1.62 | Treatment of Pain in Keloids Using Only a Long-Pulsed 1064 nm Nd:YAG Laser. ( Bakus, AD; Garden, BC; Garden, JM; Jones, VA; Lai, O; Patel, PM, 2021) |
| "The keloids were examined and the sizes were grouped into small, medium, and large keloids; the severities of symptoms were determined using the visual analog scale." | 1.51 | Demographic and clinical characteristics of keloids in an urban center in Sub-Sahara Africa. ( Belie, O; Mofikoya, BO; Ugburo, AO, 2019) |
| "Keloids are associated with small-fiber neuropathy and typically present with itching, pain, and allodynia." | 1.36 | Treatment of a painful keloid with botulinum toxin type A. ( Dave, S; Lippincott, B; Uyesugi, B, 2010) |
| "Acute pain was evaluated in all 21 patients." | 1.35 | Reduction of pain in the treatment of vascular lesions with a pulsed dye laser and pneumatic skin flattening. ( Lanigan, S, 2009) |
| "This pilot study suggests that treatment of keloid and hypertrophic scars with intra-lesional injections of collagenase is ineffective." | 1.33 | Intra-lesional injections of collagenase are ineffective in the treatment of keloid and hypertrophic scars. ( Gault, D; Kang, N; Nduka, C; Sanders, R; Sivakumar, B, 2006) |
| "Itch and pain are common presentations in keloids and are associated with abnormalities in small nerve fiber function, suggesting a small nerve fiber neuropathy." | 1.32 | Pruritus, pain, and small nerve fiber function in keloids: a controlled study. ( Chan, YH; Goh, CL; Lee, SS; Yosipovitch, G, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (7.27) | 18.7374 |
| 1990's | 3 (5.45) | 18.2507 |
| 2000's | 10 (18.18) | 29.6817 |
| 2010's | 17 (30.91) | 24.3611 |
| 2020's | 21 (38.18) | 2.80 |
| Authors | Studies |
|---|---|
| Hawash, AA | 1 |
| Ingrasci, G | 1 |
| Nouri, K | 1 |
| Yosipovitch, G | 3 |
| Chobpenthai, T | 1 |
| Poosiripinyo, T | 1 |
| Tuntarattanapong, P | 1 |
| Thanindratarn, P | 1 |
| Trathitephun, W | 1 |
| Kim, M | 1 |
| Mirsky, N | 1 |
| Spielman, A | 1 |
| Mathew, P | 1 |
| Yechieli, R | 1 |
| Tang, JC | 1 |
| Thaller, SR | 1 |
| Vanhooteghem, O | 1 |
| Erlendsson, AM | 1 |
| Rosenberg, LK | 1 |
| Lerche, CM | 1 |
| Togsverd-Bo, K | 1 |
| Wiegell, SR | 1 |
| Karmisholt, K | 1 |
| Philipsen, PA | 1 |
| Hansen, ACN | 1 |
| Janfelt, C | 1 |
| Holmes, J | 1 |
| Rossi, A | 1 |
| Haedersdal, M | 1 |
| Li, S | 1 |
| Zhang, M | 1 |
| Long, X | 1 |
| Wang, X | 2 |
| Moravej, H | 1 |
| Forghanian, A | 1 |
| Dadkhahfar, S | 1 |
| Mozafari, N | 1 |
| Attwa, E | 1 |
| Khater, MH | 1 |
| Selim, HM | 1 |
| Essam, R | 1 |
| Leszczynski, R | 1 |
| da Silva, CA | 1 |
| Pinto, ACPN | 1 |
| Kuczynski, U | 1 |
| da Silva, EM | 1 |
| Cohen, AJ | 3 |
| Talasila, S | 3 |
| Lazarevic, B | 3 |
| Banner, L | 3 |
| Gleason, L | 3 |
| Malkani, K | 3 |
| Uitto, J | 3 |
| Nikbakht, N | 3 |
| Delaleu, J | 2 |
| Charvet, E | 2 |
| Petit, A | 2 |
| Lubczyńska, A | 1 |
| Garncarczyk, A | 1 |
| Wcisło-Dziadecka, D | 1 |
| Park, SJ | 1 |
| Shin, SH | 1 |
| Koh, YG | 1 |
| Kim, GH | 1 |
| Rho, NK | 1 |
| Park, KY | 2 |
| Park, TH | 1 |
| Biazus Soares, G | 1 |
| Mahmoud, O | 1 |
| Bik, L | 1 |
| Elmzoon, I | 1 |
| Wolkerstorfer, A | 1 |
| Prens, EP | 1 |
| van Doorn, MBA | 1 |
| Belie, O | 1 |
| Ugburo, AO | 1 |
| Mofikoya, BO | 1 |
| Abou-Taleb, DAE | 1 |
| Badary, DM | 1 |
| Morales-Sánchez, MA | 1 |
| De Villafranca-Dugelby, A | 1 |
| Cruz, FJ | 1 |
| Peralta-Pedrero, ML | 1 |
| Patel, PM | 1 |
| Bakus, AD | 1 |
| Garden, BC | 1 |
| Lai, O | 1 |
| Jones, VA | 1 |
| Garden, JM | 1 |
| Falk, H | 1 |
| Vissing, M | 1 |
| Wooler, G | 1 |
| Gehl, J | 1 |
| Yang, Y | 1 |
| Xia, L | 2 |
| Ning, X | 1 |
| Hu, T | 1 |
| Xu, C | 1 |
| Liu, W | 2 |
| Wu, X | 1 |
| Liu, K | 1 |
| Lin, X | 1 |
| Gao, Z | 1 |
| Bijlard, E | 3 |
| Timman, R | 2 |
| Verduijn, GM | 1 |
| Niessen, FB | 3 |
| Hovius, SER | 2 |
| Mureau, MAM | 2 |
| Song, H | 1 |
| Tan, J | 1 |
| Fu, Q | 1 |
| Huang, L | 1 |
| Ao, M | 1 |
| Guo, QG | 1 |
| Yao, M | 1 |
| Saffari, TM | 1 |
| Van Bodegraven, EAM | 1 |
| Huygen, FJPM | 1 |
| Rasaii, S | 1 |
| Sohrabian, N | 1 |
| Gianfaldoni, S | 1 |
| Hadibarhaghtalab, M | 1 |
| Pazyar, N | 1 |
| Bakhshaeekia, A | 1 |
| Lotti, T | 1 |
| Ramirez-Pacheco, LA | 1 |
| Lange, CS | 1 |
| Matta, J | 1 |
| Seifi, V | 1 |
| Ramirez-Fort, MK | 1 |
| Feily, A | 1 |
| van Leeuwen, MC | 1 |
| Bulstra, AE | 1 |
| van Leeuwen, PA | 1 |
| van Leeuwen, MCE | 1 |
| van der Wal, MBA | 1 |
| Bulstra, AJ | 1 |
| Galindo-Garre, F | 1 |
| Molier, J | 1 |
| van Zuijlen, PPM | 1 |
| van Leeuwen, PAM | 1 |
| El-Zawahry, BM | 1 |
| Sobhi, RM | 1 |
| Bassiouny, DA | 1 |
| Tabak, SA | 1 |
| Frioui, S | 1 |
| Khachnaoui, F | 1 |
| Kouwenberg, CA | 1 |
| Hovius, SE | 1 |
| Busschbach, JJ | 1 |
| Mureau, MA | 1 |
| Usanakornkul, A | 1 |
| Burusapat, C | 1 |
| Lee, Y | 1 |
| Hong, JY | 1 |
| Chung, WS | 1 |
| Kim, MN | 1 |
| Kim, BJ | 1 |
| Chuang, GS | 1 |
| Rogers, GS | 1 |
| Zeltser, R | 1 |
| Lanigan, S | 1 |
| Tosa, M | 1 |
| Murakami, M | 1 |
| Hyakusoku, H | 1 |
| Mishra, S | 1 |
| Uyesugi, B | 1 |
| Lippincott, B | 1 |
| Dave, S | 1 |
| Kamerath, JH | 1 |
| De Luigi, AJ | 1 |
| Mandal, A | 1 |
| Imran, D | 1 |
| NAEGELI, T | 1 |
| THOREK, P | 1 |
| PANDIT, JK | 1 |
| Eishi, K | 1 |
| Bae, SJ | 1 |
| Ogawa, F | 1 |
| Hamasaki, Y | 1 |
| Shimizu, K | 1 |
| Katayama, I | 1 |
| Lim, K | 1 |
| Lee, SS | 1 |
| Chan, YH | 1 |
| Goh, CL | 1 |
| Saray, Y | 1 |
| Güleç, AT | 1 |
| Muneuchi, G | 1 |
| Suzuki, S | 1 |
| Onodera, M | 1 |
| Ito, O | 1 |
| Hata, Y | 1 |
| Igawa, HH | 1 |
| Kang, N | 1 |
| Sivakumar, B | 1 |
| Sanders, R | 1 |
| Nduka, C | 1 |
| Gault, D | 1 |
| Leung, CY | 1 |
| Roccia, L | 1 |
| Manfredi, C | 1 |
| Shigeki, S | 1 |
| Murakami, T | 1 |
| Yata, N | 1 |
| Ikuta, Y | 1 |
| Ono, N | 1 |
| Wong, TW | 1 |
| Lee, JY | 1 |
| Sheu, HM | 1 |
| Chao, SC | 1 |
| Nasilowski, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effectiveness of Dry Needling in Treating Linear Hypertrophic Scar Tissue: a Randomized Sham-controlled Trial[NCT06033430] | 80 participants (Anticipated) | Interventional | 2023-10-10 | Recruiting | |||
| Intralesional Cryotherapy With a Argon Gas Based Device for the Treatment of Keloid and Hypertrophic Scars[NCT02063243] | 33 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| Intralesional Cryotherapy for Treatment of Keloid Scars: a Prospective Evaluation[NCT01994616] | 30 participants (Actual) | Observational | 2009-01-31 | Completed | |||
| Investigation of the Effectiveness of Vibratory Stimulus in Trigger Finger Injections[NCT05405452] | Phase 4 | 1,000 participants (Anticipated) | Interventional | 2023-08-14 | Recruiting | ||
| Vibration Anesthesia for Pain Reduction During Trigger Point Injection to the Gastrocnemius[NCT03365674] | 60 participants (Actual) | Interventional | 2017-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for khellin and Pain
| Article | Year |
|---|---|
Pruritus in Keloid Scars: Mechanisms and Treatments.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Humans; Keloid; Pain; Pruritus; Quality of Life | 2021 |
Remarkable efficiency of surgical shave excision of keloids followed by intralesional injection of Bleomycin. A retrospective study of 314 cases.
Topics: Adult; Bleomycin; Humans; Injections, Intralesional; Keloid; Middle Aged; Pain; Pruritus; Retrospect | 2022 |
Laser therapy for treating hypertrophic and keloid scars.
Topics: Adrenal Cortex Hormones; Adult; Aluminum; Atrophy; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Di | 2022 |
Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis.
Topics: Cicatrix, Hypertrophic; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis.
Topics: Cicatrix, Hypertrophic; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis.
Topics: Cicatrix, Hypertrophic; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis.
Topics: Cicatrix, Hypertrophic; Keloid; Pain; Pruritus; Quality of Life | 2023 |
[Advances in the research of drug intralesional injection therapy in keloid].
Topics: Female; Humans; Injections, Intralesional; Keloid; Pain | 2018 |
[Paramount problems in the rehabilitation of severely burned patients].
Topics: Adaptation, Psychological; Adrenergic alpha-Antagonists; Burns; Contracture; Expectorants; Hemodynam | 1975 |
11 trials available for khellin and Pain
| Article | Year |
|---|---|
A one-time pneumatic jet-injection of 5-fluorouracil and triamcinolone acetonide for treatment of hypertrophic scars-A blinded randomized controlled trial.
Topics: Cicatrix, Hypertrophic; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intralesional; | 2022 |
Cold anesthesia for pain reduction during intralesional steroid injection for nodulocystic acne.
Topics: Acne Vulgaris; Anesthesia; Humans; Injections, Intralesional; Keloid; Pain; Steroids; Treatment Outc | 2023 |
Calcium Electroporation for Keloids: A First-in-Man Phase I Study.
Topics: Adult; Calcium Chloride; Electrochemotherapy; Erythema; Female; Follow-Up Studies; Humans; Keloid; M | 2021 |
Topical cryoanesthesia for the relief of pain caused by steroid injections used to treat hypertrophic scars and keloids.
Topics: Adolescent; Adult; Anesthetics, Local; Cicatrix, Hypertrophic; Cryoanesthesia; Female; Glucocorticoi | 2017 |
Intralesional cryotherapy versus excision with corticosteroid injections or brachytherapy for keloid treatment: Randomised controlled trials.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Brachytherapy; Combined Modality Therapy; Cryotherapy; | 2018 |
Intralesional triamcinolone alone or in combination with botulinium toxin A is ineffective for the treatment of formed keloid scar: A double blind controlled pilot study.
Topics: Botulinum Toxins, Type A; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; H | 2019 |
A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Argon; Cryosurgery; Elasticity; Female; Gases; Humans; H | 2014 |
Intralesional cryotherapy for treatment of keloid scars: a prospective study.
Topics: Adolescent; Adult; Aged; Asian People; Black People; Child; Cryosurgery; Female; Humans; Hypopigment | 2015 |
Ablative CO2 fractional resurfacing in treatment of thermal burn scars: an open-label controlled clinical and histopathological study.
Topics: Adolescent; Adult; Burns; Cicatrix, Hypertrophic; Female; Humans; Keloid; Lasers, Gas; Male; Middle | 2015 |
A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Do | 2017 |
Treatment of keloids and hypertrophic scars with dermojet injections of bleomycin: a preliminary study.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Bleomycin; Cicatrix, Hypertrophic; Female; Fol | 2005 |
38 other studies available for khellin and Pain
| Article | Year |
|---|---|
Outcomes of 2-octyl cyanoacrylate skin adhesives following musculoskeletal oncology surgery: A STROBE-compliant observational study.
Topics: Administration, Topical; Adult; Aged; Cyanoacrylates; Female; Hematoma; Humans; Keloid; Male; Middle | 2021 |
Evaluating Symptomatic and Psychosocial Well-being After Keloid Treatment With SCAR-Q.
Topics: Humans; Injections, Intralesional; Keloid; Pain; Pruritus; Treatment Outcome | 2022 |
Relative perfusion index: An objective, quantitative and noninvasive method for evaluating the severity of keloids.
Topics: Cross-Sectional Studies; Humans; Hypoxia; Interleukin-17; Keloid; Pain; Perfusion Index; Pruritus; S | 2022 |
Intralesional bleomycin versus intralesional triamcinolone in the treatment of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Humans; Hyperpigmentation; Injections, Intralesional; Keloid; Pai | 2022 |
Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis.
Topics: Drug Therapy, Combination; Fluorouracil; Humans; Hyperpigmentation; Injections, Intralesional; Keloi | 2022 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Effectiveness of various methods of manual scar therapy.
Topics: Cicatrix; Cicatrix, Hypertrophic; Complementary Therapies; Cupping Therapy; Dry Needling; Humans; Ke | 2023 |
Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Hum | 2023 |
Pruritus in keloid scars: mechanisms and treatments.
Topics: Cryotherapy; Humans; Inflammation; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Needle-free electronically controlled jet injection with corticosteroids in recalcitrant keloid scars: a retrospective study and patient survey.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Injections, Jet; | 2023 |
Demographic and clinical characteristics of keloids in an urban center in Sub-Sahara Africa.
Topics: Adult; Demography; Female; Humans; Keloid; Male; Nigeria; Pain; Visual Analog Scale; Wound Healing | 2019 |
Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Pain; Treatment Outcome; Verapamil | 2021 |
Methodological quality of clinical trials of keloid scars.
Topics: Cicatrix, Hypertrophic; Clinical Trials as Topic; Humans; Keloid; Pain; Quality of Life | 2020 |
Treatment of Pain in Keloids Using Only a Long-Pulsed 1064 nm Nd:YAG Laser.
Topics: Humans; Keloid; Lasers, Solid-State; Low-Level Light Therapy; Pain; Treatment Outcome | 2021 |
Enhanced Drug Permeation into Human Keloid Tissues by Sonophoresis-Assisted Microneedling.
Topics: Humans; Keloid; Pain; Pharmaceutical Preparations; Treatment Outcome | 2021 |
Comparative efficacy of intralesional triamcinolone acetonide injection during early and static stage of pathological scarring.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Glucocorticoids; H | 2019 |
Sensory perception and nerve fibre innervation in patients with keloid scars: an investigative study.
Topics: Biopsy; Humans; Hyperalgesia; Keloid; Nerve Fibers; Neuralgia; Pain; Pain Measurement; Skin | 2018 |
[External branch spinal nerve paralysis on keloid scar].
Topics: Humans; Keloid; Male; Pain; Paralysis; Plastic Surgery Procedures; Spinal Nerves; Young Adult | 2016 |
Burden of Keloid Disease: A Cross-sectional Health-related Quality of Life Assessment.
Topics: Adolescent; Adult; Cross-Sectional Studies; Elasticity; Emotions; Female; Humans; Keloid; Male; Midd | 2017 |
Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment.
Topics: Adolescent; Adult; Anesthesia; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans; Injections, | 2017 |
Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment.
Topics: Adolescent; Adult; Anesthesia; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans; Injections, | 2017 |
Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment.
Topics: Adolescent; Adult; Anesthesia; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans; Injections, | 2017 |
Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment.
Topics: Adolescent; Adult; Anesthesia; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans; Injections, | 2017 |
Poiseuille's law and large-bore needles: insights into the delivery of corticosteroid injections in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Anesthetics, Local; Humans; Injections, Intralesional; Keloid; Needles; Pai | 2008 |
Reduction of pain in the treatment of vascular lesions with a pulsed dye laser and pneumatic skin flattening.
Topics: Adult; Child; Humans; Intermittent Pneumatic Compression Devices; Keloid; Keratosis; Lasers, Dye; Lo | 2009 |
Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Female; Humans; Injections, Intralesional; Kel | 2009 |
Safe and less painful injection of triamcenolone acetonide into a keloid--a technique.
Topics: Anesthetics, Local; Bupivacaine; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Lidocai | 2010 |
Treatment of a painful keloid with botulinum toxin type A.
Topics: Aged, 80 and over; Botulinum Toxins, Type A; Female; Humans; Keloid; Neuromuscular Agents; Pain | 2010 |
Analgesic benefit of niacin for shrapnel wound pain in war veteran.
Topics: Aged, 80 and over; Analgesia; Blast Injuries; Cicatrix, Hypertrophic; Humans; Hyperlipidemias; Hypol | 2010 |
Painless steroid injections for hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Humans; Injections; Keloid; Pain; Steroids | 2003 |
[SECONDARY EFFECTS, SYMPTOMS AND UNDESIRABLE EARLY SEQUELAE IN SURGERY OF THE ABDOMINAL CAVITY. GENERAL PATHOLOGICAL AND CLINICAL PROBLEMS].
Topics: Abdomen; Abdominal Cavity; Anuria; Blood Glucose; Enterocolitis; Humans; Keloid; Laparotomy; Pain; P | 1963 |
PROTEOLYTIC ENZYMES IN WOUND REPAIR; IMMEDIATE POSTOPERATIVE EFFECTS.
Topics: Biomedical Research; Drug Therapy; Edema; Hematoma; Humans; Keloid; Pain; Peptide Hydrolases; Postop | 1964 |
Silicone gel sheets relieve pain and pruritus with clinical improvement of keloid: possible target of mast cells.
Topics: Administration, Topical; Adult; Aged; Biopsy, Needle; Female; Humans; Immunohistochemistry; Keloid; | 2003 |
Painless steroid injections for hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Pain; Steroids; Therapy, Computer | 2004 |
Pruritus, pain, and small nerve fiber function in keloids: a controlled study.
Topics: Adult; Female; Humans; Keloid; Male; Middle Aged; Nerve Fibers; Pain; Pain Threshold; Pruritus; Sens | 2004 |
Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients.
Topics: Adolescent; Adult; Aged; Asian People; Child; Child, Preschool; Cicatrix; Female; Glucocorticoids; H | 2006 |
Intra-lesional injections of collagenase are ineffective in the treatment of keloid and hypertrophic scars.
Topics: Adult; Anti-Inflammatory Agents; Blister; Child; Cicatrix, Hypertrophic; Drug Administration Schedul | 2006 |
[1st observations on the side effects of soft-laser therapy].
Topics: Female; Humans; Keloid; Laser Therapy; Lasers; Pain; Sensation; Tachycardia; Voice Quality | 1983 |
Treatment of keloid and hypertrophic scars by iontophoretic transdermal delivery of tranilast.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Animals; Child; Cicatrix; | 1997 |
Pain-free intralesional injection of triamcinolone for the treatment of keloid.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Middle Aged; Needles; Pain; Pain Measure | 1999 |
Relief of pain and itch associated with keloids on treatment with oxpentifylline.
Topics: Adult; Aged; Dermatologic Agents; Female; Humans; Keloid; Male; Pain; Pentoxifylline; Pruritus | 1999 |