khellin has been researched along with Necrosis in 12 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we evaluated the in vitro cytotoxic effect of PDT at 5J/cm(2) and 10J/cm(2) of red light (633 ± 3nm) using 5-aminolevulinic acid (ALA) and methyl aminolevulinate (MAL) with and without DW, on keloid fibroblasts compared to normal skin fibroblasts." | 3.77 | Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy. ( Allan, D; Allan, E; Bayat, A; Colthurst, J; Sebastian, A, 2011) |
| "Keloids are considered the manifestation of a fibroproliferative disease characterized by chronic inflammation that is induced following skin injury." | 1.91 | IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation. ( Chao, H; He, J; Hsu, P; Liu, H; Ma, H; Tang, Q; Wu, R; Xu, S; Zeng, R; Zheng, L; Zhou, Y, 2023) |
| "Keloids are a hyperproliferative response of connective tissue in response to trauma." | 1.33 | Defective induction of senescence during wound healing is a possible mechanism of keloid formation. ( Blazić, TM; Brajac, I, 2006) |
| "Keloids are collagenous lesions acquired as a result of abnormal wound heating." | 1.29 | Apoptosis, necrosis, and proliferation: possible implications in the etiology of keloids. ( Appleton, I; Brown, NJ; Willoughby, DA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chao, H | 1 |
| Zheng, L | 1 |
| Hsu, P | 1 |
| He, J | 1 |
| Wu, R | 1 |
| Xu, S | 1 |
| Zeng, R | 1 |
| Zhou, Y | 1 |
| Ma, H | 1 |
| Liu, H | 1 |
| Tang, Q | 1 |
| Bux, S | 1 |
| Madaree, A | 1 |
| Wazen, JJ | 1 |
| Wycherly, B | 1 |
| Daugherty, J | 1 |
| Sebastian, A | 1 |
| Allan, E | 1 |
| Allan, D | 1 |
| Colthurst, J | 1 |
| Bayat, A | 1 |
| Blazić, TM | 1 |
| Brajac, I | 1 |
| Weerda, H | 1 |
| Siegert, R | 1 |
| Kahle, B | 1 |
| Zilow, E | 1 |
| Springer, W | 1 |
| Näher, H | 1 |
| Appleton, I | 1 |
| Brown, NJ | 1 |
| Willoughby, DA | 1 |
| Fukuda, O | 1 |
| Yamada, A | 1 |
| Solomon, LM | 1 |
| Caputo, R | 1 |
| Davis, J | 1 |
| Evans, D | 1 |
| Greenberg, M | 1 |
| Hill, C | 1 |
| Keuer, E | 1 |
| Koya, D | 1 |
| Morgan, N | 1 |
| Pedvis-Leftick, A | 1 |
| Abdel-Fattah, AM | 1 |
| Flowers, RS | 1 |
1 review available for khellin and Necrosis
| Article | Year |
|---|---|
Complications of bone-anchored hearing devices.
Topics: Hearing Aids; Hearing Loss, Conductive; Hematoma; Hemorrhage; Humans; Hygiene; Keloid; Necrosis; Pai | 2011 |
11 other studies available for khellin and Necrosis
| Article | Year |
|---|---|
IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation.
Topics: Animals; Down-Regulation; Extracellular Matrix; Fibroblasts; Humans; Janus Kinases; Keloid; Mice; Ne | 2023 |
Keloids show regional distribution of proliferative and degenerate connective tissue elements.
Topics: Adolescent; Adult; Cell Proliferation; Child; Collagen; DNA; Extracellular Matrix; Female; Fibroblas | 2010 |
Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy.
Topics: Adult; Aged; Aminolevulinic Acid; Apoptosis; Blotting, Western; Case-Control Studies; Caspase 3; Cel | 2011 |
Defective induction of senescence during wound healing is a possible mechanism of keloid formation.
Topics: Amphotericin B; Apoptosis; Cell Proliferation; Cellular Senescence; Extracellular Matrix; Fibroblast | 2006 |
Complications in otoplastic surgery and their treatment.
Topics: Ear Deformities, Acquired; Ear, External; Hematoma; Humans; Keloid; Necrosis; Pain, Postoperative; P | 1994 |
[Cicatricial keloids after Waterhouse-Friderichsen syndrome].
Topics: Cicatrix, Hypertrophic; Follow-Up Studies; Hemorrhage; Humans; Infant; Keloid; Male; Necrosis; Skin; | 1994 |
Apoptosis, necrosis, and proliferation: possible implications in the etiology of keloids.
Topics: Acridine Orange; Apoptosis; Cell Division; Humans; In Situ Hybridization; Keloid; Necrosis; Prolifer | 1996 |
Reconstruction of the microtic ear with autogenous cartilage.
Topics: Age Factors; Bacterial Infections; Cartilage; Child; Child, Preschool; Ear, External; Female; Humans | 1978 |
Miscellaneous dermatoses.
Topics: Acanthosis Nigricans; Adolescent; Athletic Injuries; Dermatomycoses; Female; Granuloma; Humans; Icht | 1978 |
Unusual complications of triamcinolone injected keloids: tissue necrosis and systemic corticosteroid effects.
Topics: Adolescent; Adult; Cushing Syndrome; Female; Humans; Keloid; Necrosis; Triamcinolone Acetonide | 1976 |
Unexpected postoperative problems in skin grafting.
Topics: Cellulitis; Cicatrix; Contracture; Hematoma; Humans; Infections; Keloid; Necrosis; Postoperative Com | 1970 |