khellin has been researched along with Melanoma in 27 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to test the effect of khellin and KUVA on proliferation and melanogenesis of normal human melanocytes and Mel-1 melanoma cells in vitro." | 7.72 | KUVA (khellin plus ultraviolet A) stimulates proliferation and melanogenesis in normal human melanocytes and melanoma cells in vitro. ( Carlie, G; Hulley, PA; Kidson, SH; Ntusi, NB, 2003) |
| "Visnagin was induced apoptosis due to the intracellular generation of reactive oxygen species (ROS) and showed an apoptotic effect against HT 144 cell lines by 25." | 5.51 | The anticancer activity of visnagin, isolated from Ammi visnaga L., against the human malignant melanoma cell lines, HT 144. ( Aydoğmuş-Öztürk, F; Beyazit, N; Choudhary, MI; Günaydın, K; Jahan, H, 2019) |
| "The aim of this study was to test the effect of khellin and KUVA on proliferation and melanogenesis of normal human melanocytes and Mel-1 melanoma cells in vitro." | 3.72 | KUVA (khellin plus ultraviolet A) stimulates proliferation and melanogenesis in normal human melanocytes and melanoma cells in vitro. ( Carlie, G; Hulley, PA; Kidson, SH; Ntusi, NB, 2003) |
| "Visnagin was induced apoptosis due to the intracellular generation of reactive oxygen species (ROS) and showed an apoptotic effect against HT 144 cell lines by 25." | 1.51 | The anticancer activity of visnagin, isolated from Ammi visnaga L., against the human malignant melanoma cell lines, HT 144. ( Aydoğmuş-Öztürk, F; Beyazit, N; Choudhary, MI; Günaydın, K; Jahan, H, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (51.85) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 3 (11.11) | 29.6817 |
| 2010's | 6 (22.22) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Aydoğmuş-Öztürk, F | 1 |
| Jahan, H | 1 |
| Beyazit, N | 1 |
| Günaydın, K | 1 |
| Choudhary, MI | 1 |
| Carlie, G | 1 |
| Ntusi, NB | 1 |
| Hulley, PA | 1 |
| Kidson, SH | 1 |
| Dore, R | 1 |
| McClelland, K | 1 |
| Brady, A | 1 |
| Reid, P | 1 |
| Houghton, J | 1 |
| Nakamura, Y | 1 |
| Ishitsuka, Y | 1 |
| Fujisawa, Y | 1 |
| Konishi, R | 1 |
| Maruyama, H | 1 |
| Inoue, S | 1 |
| Okiyama, N | 1 |
| Watanabe, R | 1 |
| Fujimoto, M | 1 |
| Wadhwa, R | 1 |
| Priyandoko, D | 1 |
| Gao, R | 1 |
| Widodo, N | 1 |
| Nigam, N | 1 |
| Li, L | 1 |
| Ahn, HM | 1 |
| Yun, CO | 1 |
| Ando, N | 1 |
| Mahe, C | 1 |
| Kaul, SC | 1 |
| Cicchi, R | 1 |
| Sestini, S | 1 |
| De Giorgi, V | 1 |
| Massi, D | 1 |
| Lotti, T | 1 |
| Pavone, FS | 1 |
| Lazarus, M | 1 |
| Kaufman, H | 1 |
| Liodaki, E | 1 |
| Eirini, L | 1 |
| Liodakis, E | 1 |
| Emmanouil, L | 1 |
| Papadopoulos, O | 1 |
| Othonas, P | 1 |
| Machens, HG | 1 |
| Hans-Günther, M | 1 |
| Papadopulos, NA | 1 |
| Nikolaos, PA | 1 |
| Zhang, X | 1 |
| VILANOVA, X | 1 |
| MATO, J | 1 |
| JOHNSON, WC | 1 |
| HELWIG, EB | 1 |
| SCHULZ, MD | 1 |
| WANG, CC | 1 |
| Theopold, C | 1 |
| Pritchard, S | 1 |
| McGrouther, DA | 1 |
| Bayat, A | 1 |
| Pircher, FJ | 1 |
| Anderson, B | 1 |
| Cavanaugh, PJ | 1 |
| Sharp, KW | 1 |
| Thomas, JR | 1 |
| Doyle, JA | 1 |
| Parlette, HL | 1 |
| Hendrix, JD | 1 |
| Dompmartin, A | 1 |
| Zabel, M | 1 |
| Hiss, Y | 1 |
| Shafir, R | 1 |
| Gay, S | 1 |
| Müller, PK | 1 |
| Meigel, WN | 1 |
| Kühn, K | 1 |
| Morgan, JE | 1 |
| Gilchrest, B | 1 |
| Goldwyn, RM | 1 |
| Smoller, BR | 1 |
| McNutt, NS | 1 |
| Hsu, A | 1 |
| Ronnen, M | 1 |
| Sokol, MS | 1 |
| Huszar, M | 1 |
| Kahana, M | 1 |
| Schewach-Millet, M | 1 |
| Morelli, JG | 1 |
| Parrish, JA | 2 |
| Walsh, J | 1 |
| Morelli, J | 1 |
| Conley, J | 1 |
8 reviews available for khellin and Melanoma
| Article | Year |
|---|---|
Dark Skin Representation in Mobile Applications for Dermatology Education: A Scoping Review.
Topics: Dermatology; Humans; Keloid; Melanoma; Mobile Applications; Skin Neoplasms; Skin Pigmentation | 2023 |
An association between corticosteroid use and melanoma recurrence: a case report and review of the literature.
Topics: Adrenal Cortex Hormones; Aged; Carcinoma in Situ; Carcinoma, Basal Cell; Humans; Keloid; Male; Melan | 2012 |
PET scanning in plastic and reconstructive surgery.
Topics: Breast Neoplasms; Diabetic Foot; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Ke | 2012 |
Genome-wide association study of skin complex diseases.
Topics: Alopecia; Carcinoma, Basal Cell; Dermatitis, Atopic; Female; Genetic Predisposition to Disease; Geno | 2012 |
The therapeutic uses of topical vitamin A acid.
Topics: Acne Vulgaris; Animals; Callosities; Cocarcinogenesis; Fox-Fordyce Disease; Humans; Ichthyosis; Kelo | 1981 |
Cutaneous and cartilaginous lesions of the auricle.
Topics: Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cysts; Ear Cartilage; Ear Diseas | 1995 |
Skin pigmentation. Current concepts and relevance to plastic surgery.
Topics: Adolescent; Adult; Dermabrasion; Female; Ficusin; Humans; Keloid; Male; Melanins; Melanocyte-Stimula | 1975 |
Lasers in dermatology: a selective historical review.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatology; Humans; Keloid; Laser Therapy; Melanom | 1985 |
19 other studies available for khellin and Melanoma
| Article | Year |
|---|---|
The anticancer activity of visnagin, isolated from Ammi visnaga L., against the human malignant melanoma cell lines, HT 144.
Topics: Ammi; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromones; Furans; Hum | 2019 |
KUVA (khellin plus ultraviolet A) stimulates proliferation and melanogenesis in normal human melanocytes and melanoma cells in vitro.
Topics: Blotting, Northern; Blotting, Western; Cell Division; Cell Line, Tumor; Cells, Cultured; Fibroblasts | 2003 |
Keloidal atypical fibroxanthoma of the scalp.
Topics: Aged; Biomarkers, Tumor; Carcinoma, Squamous Cell; Diagnosis, Differential; Humans; Keloid; Melanoma | 2023 |
Pelvic reactive lymphadenopathy mimicking lymph node metastasis of heel malignant melanoma.
Topics: Diagnosis, Differential; Heel; Humans; Keloid; Lymphadenopathy; Lymphatic Metastasis; Male; Melanoma | 2018 |
Stress chaperone mortalin regulates human melanogenesis.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Diglycerides; HSP70 Heat-Shock Proteins; Humans; Hy | 2016 |
Nonlinear laser imaging of skin lesions.
Topics: Adult; Aged; Carcinoma, Basal Cell; Female; Humans; Keloid; Lasers; Male; Melanoma; Microscopy, Conf | 2008 |
[Melanoma treated at the initial site with formation of a keloid scar, with residual lymph node metastases].
Topics: Cicatrix; Humans; Keloid; Lymph Nodes; Lymphatic Metastasis; Melanoma | 1952 |
HISTOCHEMISTRY OF THE ACID MUCOPOLYSACCHARIDES OF SKIN IN NORMAL AND IN CERTAIN PATHOLOGIC CONDITIONS.
Topics: Adenocarcinoma, Mucinous; Calcinosis; Classification; Coloring Agents; Glycosaminoglycans; Histocyto | 1963 |
RADIOTHERAPY OF LESIONS OF THE LIDS.
Topics: Conjunctiva; Conjunctivitis; Cornea; Eyelashes; Eyelids; Humans; Keloid; Lens, Crystalline; Lymphoma | 1964 |
Keloid scar harbouring malignant blue naevus emphasises the need for excision biopsy and routine histology.
Topics: Aged; Diagnosis, Differential; Ear Neoplasms; Ear, External; Humans; Keloid; Male; Melanoma; Nevus, | 2009 |
Experiences with a solid state detector for surface counting of phosphorus-32.
Topics: Ciliary Body; Eye Neoplasms; Humans; Keloid; Melanoma; Neoplasm Metastasis; Phosphorus Isotopes; Rad | 1967 |
[Nodules of the external ear].
Topics: Angiolymphoid Hyperplasia with Eosinophilia; Calcinosis; Carcinoma, Basal Cell; Carcinoma, Squamous | 1999 |
[Scar keloids, eruptive xanthomas, mollusca contagiosa, juvenile melanoma, circumscript pretibial myxedema].
Topics: Adolescent; Adult; Aged; Female; Humans; Keloid; Melanoma; Middle Aged; Molluscum Contagiosum; Myxed | 1978 |
"Pseudomelanoma" in a keloid.
Topics: Adult; Diagnosis, Differential; Female; Humans; Keloid; Melanoma; Nevus, Pigmented; Recurrence; Skin | 1978 |
[The polymorphism of collagen. New viewpoints on the structure and function of connective tissue].
Topics: Age Factors; Amino Acid Sequence; Antibodies; Aorta; Cartilage; Chemical Phenomena; Chemistry; Colla | 1976 |
HMB-45 recognizes stimulated melanocytes.
Topics: Antibodies, Monoclonal; Antigens; Binding Sites, Antibody; Cicatrix; Cytoplasm; Ecchymosis; Fibroma; | 1989 |
Pseudomelanoma following treatment with surgical excision and intralesional triamcinolone acetonide to prevent keloid formation.
Topics: Adult; Female; Humans; Keloid; Melanoma; Neoplasm Recurrence, Local; Nevus, Pigmented; Skin Neoplasm | 1986 |
Laser-tissue interactions and their clinical applications.
Topics: Forecasting; Hematoporphyrin Photoradiation; Humans; Keloid; Laser Therapy; Melanoma; Nevus, Pigment | 1986 |
Irradiation as an etiologic factor in the development of melanoma.
Topics: Adult; Aged; Burns; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Head and Neck Neoplasms; Hum | 1970 |