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khellin and Kidney Stones

khellin has been researched along with Kidney Stones in 7 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Research Excerpts

ExcerptRelevanceReference
"In patients with urolithiasis "Nephrolith" has a favourable influence on many parameters which are responsible for the development of renal calculi."2.64[Experiences with nephrolith in the treatment of patients with kidney calculi]. ( Modliński, L, 1977)
" To date, no information is available about the pharmacokinetic (PK) properties of visnagin."1.38Nonlinear pharmacokinetics of visnagin in rats after intravenous bolus administration. ( Butterweck, V; Haug, KG; Hochhaus, G; Weber, B, 2012)
" After determination of the pharmacokinetic properties of visnagin after intravenous bolus administration in rats, the aim of the present study was to evaluate the pharmacokinetic properties of visnagin and an aqueous Ammi visnaga extract after oral administration in rats."1.38Pharmacokinetic evaluation of visnagin and Ammi visnaga aqueous extract after oral administration in rats. ( Butterweck, V; Haug, KG; Hochhaus, G; Weber, B, 2012)
"Hyperoxaluria was induced in male Sprague-Dawley rats by giving 0."1.37Prevention of renal crystal deposition by an extract of Ammi visnaga L. and its constituents khellin and visnagin in hyperoxaluric rats. ( Butterweck, V; Chow, N; Khan, SR; Vanachayangkul, P, 2011)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vanachayangkul, P2
Byer, K1
Khan, S1
Butterweck, V4
Chow, N1
Khan, SR1
Haug, KG2
Weber, B2
Hochhaus, G2
Kilicaslan, I1
Coskun, S1
Modliński, L1
Heyen, CA1
Delk, PR1
Bull, MJ1
Weaver, DD1

Trials

1 trial available for khellin and Kidney Stones

ArticleYear
[Experiences with nephrolith in the treatment of patients with kidney calculi].
    Zeitschrift fur Urologie und Nephrologie, 1977, Volume: 70, Issue:6

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Calcium; Child; Child, Preschool; Clinical Trials as

1977

Other Studies

6 other studies available for khellin and Kidney Stones

ArticleYear
An aqueous extract of Ammi visnaga fruits and its constituents khellin and visnagin prevent cell damage caused by oxalate in renal epithelial cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:8-9

    Topics: Ammi; Animals; Calcium Oxalate; Cell Line; Cell Survival; Dogs; Epithelial Cells; Fruit; Khellin; Ki

2010
Prevention of renal crystal deposition by an extract of Ammi visnaga L. and its constituents khellin and visnagin in hyperoxaluric rats.
    Urological research, 2011, Volume: 39, Issue:3

    Topics: Administration, Oral; Ammi; Animals; Calcium Oxalate; Disease Models, Animal; Hyperoxaluria; Khellin

2011
Nonlinear pharmacokinetics of visnagin in rats after intravenous bolus administration.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Jan-23, Volume: 45, Issue:1-2

    Topics: Animals; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug;

2012
Spontaneous stone passage: is it Ammi visnaga effect?
    Urological research, 2012, Volume: 40, Issue:6

    Topics: Ammi; Humans; Khellin; Kidney Calculi; Male; Middle Aged; Phytotherapy; Remission, Spontaneous

2012
Pharmacokinetic evaluation of visnagin and Ammi visnaga aqueous extract after oral administration in rats.
    Planta medica, 2012, Volume: 78, Issue:17

    Topics: Administration, Oral; Ammi; Animals; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy,

2012
A report of an apparent new genetic syndrome consisting of joint contractures, keloids, large optic cup-to-disc ratio and renal stones.
    American journal of medical genetics. Part A, 2008, Dec-15, Volume: 146A, Issue:24

    Topics: Abnormalities, Multiple; Adult; Child; Contracture; Female; Humans; Joints; Keloid; Kidney Calculi;

2008
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