khellin and Kidney Stones
khellin has been researched along with Kidney Stones in 7 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"In patients with urolithiasis "Nephrolith" has a favourable influence on many parameters which are responsible for the development of renal calculi." | 2.64 | [Experiences with nephrolith in the treatment of patients with kidney calculi]. ( Modliński, L, 1977) |
" To date, no information is available about the pharmacokinetic (PK) properties of visnagin." | 1.38 | Nonlinear pharmacokinetics of visnagin in rats after intravenous bolus administration. ( Butterweck, V; Haug, KG; Hochhaus, G; Weber, B, 2012) |
" After determination of the pharmacokinetic properties of visnagin after intravenous bolus administration in rats, the aim of the present study was to evaluate the pharmacokinetic properties of visnagin and an aqueous Ammi visnaga extract after oral administration in rats." | 1.38 | Pharmacokinetic evaluation of visnagin and Ammi visnaga aqueous extract after oral administration in rats. ( Butterweck, V; Haug, KG; Hochhaus, G; Weber, B, 2012) |
"Hyperoxaluria was induced in male Sprague-Dawley rats by giving 0." | 1.37 | Prevention of renal crystal deposition by an extract of Ammi visnaga L. and its constituents khellin and visnagin in hyperoxaluric rats. ( Butterweck, V; Chow, N; Khan, SR; Vanachayangkul, P, 2011) |
Research
Studies (7)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (14.29) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (14.29) | 29.6817 |
2010's | 5 (71.43) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Vanachayangkul, P | 2 |
Byer, K | 1 |
Khan, S | 1 |
Butterweck, V | 4 |
Chow, N | 1 |
Khan, SR | 1 |
Haug, KG | 2 |
Weber, B | 2 |
Hochhaus, G | 2 |
Kilicaslan, I | 1 |
Coskun, S | 1 |
Modliński, L | 1 |
Heyen, CA | 1 |
Delk, PR | 1 |
Bull, MJ | 1 |
Weaver, DD | 1 |
Trials
1 trial available for khellin and Kidney Stones
Article | Year |
---|---|
[Experiences with nephrolith in the treatment of patients with kidney calculi].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Calcium; Child; Child, Preschool; Clinical Trials as | 1977 |
Other Studies
6 other studies available for khellin and Kidney Stones
Article | Year |
---|---|
An aqueous extract of Ammi visnaga fruits and its constituents khellin and visnagin prevent cell damage caused by oxalate in renal epithelial cells.
Topics: Ammi; Animals; Calcium Oxalate; Cell Line; Cell Survival; Dogs; Epithelial Cells; Fruit; Khellin; Ki | 2010 |
Prevention of renal crystal deposition by an extract of Ammi visnaga L. and its constituents khellin and visnagin in hyperoxaluric rats.
Topics: Administration, Oral; Ammi; Animals; Calcium Oxalate; Disease Models, Animal; Hyperoxaluria; Khellin | 2011 |
Nonlinear pharmacokinetics of visnagin in rats after intravenous bolus administration.
Topics: Animals; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; | 2012 |
Spontaneous stone passage: is it Ammi visnaga effect?
Topics: Ammi; Humans; Khellin; Kidney Calculi; Male; Middle Aged; Phytotherapy; Remission, Spontaneous | 2012 |
Pharmacokinetic evaluation of visnagin and Ammi visnaga aqueous extract after oral administration in rats.
Topics: Administration, Oral; Ammi; Animals; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, | 2012 |
A report of an apparent new genetic syndrome consisting of joint contractures, keloids, large optic cup-to-disc ratio and renal stones.
Topics: Abnormalities, Multiple; Adult; Child; Contracture; Female; Humans; Joints; Keloid; Kidney Calculi; | 2008 |