khellin has been researched along with Inflammation in 63 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the effect of intralesional tamoxifen on keloids, particularly on the concentration of fibroblasts, dermal inflammatory infiltrate, and collagen degeneration." | 7.85 | Morphological and morphometric analysis of the effects of intralesional tamoxifen on keloids. ( Alencar, AP; da Silva, BB; Filho, LL; Soares-Lopes, IM; Soares-Lopes, LR, 2017) |
| "Visnagin (VIS) is a natural bioactive component of Ammi visnaga, with promising radical scavenging and anti-inflammatory activities." | 5.62 | Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats. ( Abukhalil, MH; Al-Amarat, W; Al-Swailmi, FK; Aladaileh, SH; Alanazi, KM; Alfwuaires, MA; Algefare, AI; Althunibat, OY; Hussein, OE; Kamel, EM; Mahmoud, AM; Saghir, SA, 2021) |
| " Targeting aberrant glucose metabolism with shikonin, a pyruvate kinase M2 inhibitor, dampened NLRP3-mediated inflammation (cleaved caspase-1 [P < 0." | 3.96 | Regulation of glycolysis and the Warburg effect in wound healing. ( Abdullahi, A; Auger, C; Barayan, D; Jeschke, MG; Vinaik, R, 2020) |
| "The aim of this study was to evaluate the effect of intralesional tamoxifen on keloids, particularly on the concentration of fibroblasts, dermal inflammatory infiltrate, and collagen degeneration." | 3.85 | Morphological and morphometric analysis of the effects of intralesional tamoxifen on keloids. ( Alencar, AP; da Silva, BB; Filho, LL; Soares-Lopes, IM; Soares-Lopes, LR, 2017) |
| "Keloids and hypertrophic scars are pathological cutaneous scars." | 2.82 | Role of Inflammasomes in Keloids and Hypertrophic Scars-Lessons Learned from Chronic Diabetic Wounds and Skin Fibrosis. ( Huang, C; Ogawa, R, 2022) |
| "Coupled with few effective treatments in keloid at present, we have focused on the immunological mechanisms of keloids with an aim to unravel some new therapeutic approaches in the future." | 2.72 | Emerging insights into the immunological aspects of keloids. ( Fu, S; Ogawa, R; Wu, H; Yu, Y; Zhang, Q, 2021) |
| "Hypertrophic scars and keloids may complicate wound healing secondary to trauma or surgery." | 2.69 | Treatment of inflamed hypertrophic scars using intralesional 5-FU. ( Fitzpatrick, RE, 1999) |
| "Keloids and hypertrophic scars are pathological scars that result from aberrant wound healing." | 2.66 | The Roles of Inflammation in Keloid and Hypertrophic Scars. ( Cai, JQ; Cao, Y; Liu, YQ; Shen, XZ; Shi, P; Sun, Q; Tan, WQ; Wang, ZC; Zhao, WY, 2020) |
| "Keloids are considered as benign fibroproliferative skin tumors growing beyond the site of the original dermal injury." | 2.61 | Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies. ( Bayat, A; Khumalo, N; Tan, S, 2019) |
| "Keloids are common cutaneous pathological scars that are characterised by the histological accumulation of fibroblasts, collagen fibres, and clinically significant invasive growth." | 2.49 | Roles of lipid metabolism in keloid development. ( Huang, C; Ogawa, R, 2013) |
| "While conventional antiscarring agents target the fibroplasia phase, others such as tamoxifen ,calcium channel blockers, and imidazolaquinolines targets various phases of the scarring process ." | 2.48 | An overview of biological basis of pathologic scarring. ( Adeyemo, WL; Mofikoya, BO; Ugburo, AO, 2012) |
| " Definite dosage reductions can be achieved by suitable radioprotective measures." | 2.37 | [Radiation treatment of benign diseases--indications, results and technic]. ( Hassenstein, E, 1986) |
| "This abnormal hyperplasia is due to the chronic inflammatory reaction in the dermis caused by injury." | 1.91 | [Status of diagnosis and treatment of hypertrophic scar and keloid]. ( Zang, MQ, 2023) |
| "Keloid is a pathological scar formed by abnormal wound healing, characterized by the persistence of local inflammation and excessive collagen deposition, where the intensity of inflammation is positively correlated with the size of the scar formation." | 1.91 | Revealing the roles of glycosphingolipid metabolism pathway in the development of keloid: a conjoint analysis of single-cell and machine learning. ( Chen, G; Chen, L; Chi, H; Cui, Z; Du, Y; Gao, B; Song, B; Yu, Z; Zheng, Y; Zhu, Y, 2023) |
| "Keloid-associated pruritus is a common manifestation and has negative impacts on quality of life." | 1.91 | Pruritus in keloid scars: mechanisms and treatments. ( Biazus Soares, G; Mahmoud, O; Yosipovitch, G, 2023) |
| "Among 56 treated keloids, 89." | 1.91 | Ear keloids: An innovative 3-steps combined treatment. ( Alessandro, G; Bruno, B; Claudio, C; Daniele, B; Domenico, P; Fabrizio, M; Giuliana, C; Matteo, TC, 2023) |
| "Keloid is considered as a tumor-like skin disease with multiple aetiologies including immunological factors and mechanical microenvironment." | 1.72 | Important role of mechanical microenvironment on macrophage dysfunction during keloid pathogenesis. ( Gao, Z; Liu, W; Wang, W; Wu, X; Zhou, B, 2022) |
| "Keloids are benign fibroproliferative skin disorders characterized by chronic inflammation." | 1.72 | Secondary Cutaneous Ossification in Keloids of the Lower Abdomen: A Report of Two Cases. ( Ansai, SI; Ogawa, R; Tosa, M, 2022) |
| "Keloid is an abnormal fibrotic disease after cutaneous injury characterized by exaggerated scar tissue formation, which often extends beyond the boundaries of the original wound." | 1.72 | IL-17 Induces Autophagy Dysfunction to Promote Inflammatory Cell Death and Fibrosis in Keloid Fibroblasts ( Cho, KH; Cho, ML; Choi, JW; Lee, AR; Lee, CR; Lee, JH; Lee, SY, 2022) |
| "Visnagin (VIS) is a natural bioactive component of Ammi visnaga, with promising radical scavenging and anti-inflammatory activities." | 1.62 | Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats. ( Abukhalil, MH; Al-Amarat, W; Al-Swailmi, FK; Aladaileh, SH; Alanazi, KM; Alfwuaires, MA; Algefare, AI; Althunibat, OY; Hussein, OE; Kamel, EM; Mahmoud, AM; Saghir, SA, 2021) |
| "Visnagin (VIS) is a furanochromone with promising antioxidant and anti-inflammatory effects; however, its protective efficacy against Pb toxicity has not been investigated." | 1.62 | Effect of Visnagin on Altered Steroidogenesis and Spermatogenesis, and Testicular Injury Induced by the Heavy Metal Lead. ( Ajarem, JS; Allam, AA; Allam, GA; Hegazy, AK; Mahmoud, AM; Maodaa, SN, 2021) |
| "Keloid is an aberrant scarring process of the skin, characterized by excessive extracellular matrix synthesis and deposition." | 1.62 | Multi-Antigen Imaging Reveals Inflammatory DC, ADAM17 and Neprilysin as Effectors in Keloid Formation. ( Bauerschmitz, J; Baur, AS; Fröhlich, W; Kirr, M; Ostalecki, C; Pitiot, A; Plosnita, B; Rath, M; Schliep, S, 2021) |
| "Keloid is a hyperplastic pathological scar of body caused by infection, trauma, and surgery or formed spontaneously for unknown reasons." | 1.62 | [Research advances on inflammatory responses involved in keloid development]. ( Lei, JA; Qin, ZL; Zhou, Y, 2021) |
| "Keloid is a disease that is difficult to cure and has a high recurrence rate." | 1.56 | [Examining the pathogenesis and therapeutic strategy of keloids from the perspective of systemic inflammation]. ( Cao, ZD; Liu, W, 2020) |
| "Keloid is a representative chronic fibroproliferative condition that occurs after tissue injury." | 1.56 | Contribution of Autophagy-Notch1-Mediated NLRP3 Inflammasome Activation to Chronic Inflammation and Fibrosis in Keloid Fibroblasts. ( Kang, H; Kim, JE; Kim, SK; Lee, DG; Lee, KJ; Lee, S; Lee, YJ; Park, H; Park, SH, 2020) |
| "Keloids and hypertrophic scars are fibroproliferative disorders (FPDs) of the skin that result from abnormal healing of injured or irritated skin." | 1.43 | Endothelial dysfunction may play a key role in keloid and hypertrophic scar pathogenesis - Keloids and hypertrophic scars may be vascular disorders. ( Akaishi, S; Ogawa, R, 2016) |
| "The study included patients with 1) liver cirrhosis, showing hyperammonemia and inflammation; 2) non-alcoholic fatty liver disease (NAFLD) showing inflammation but not hyperammonemia; 3) non-alcoholic steatohepatitis (NASH) showing inflammation and very mild hyperammonemia; 4) psoriasis, showing inflammation but not hyperammonemia; 5) keloids, showing both inflammation and hyperammonemia and 6) controls without inflammation or hyperammonemia." | 1.38 | Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy. ( Cassinello, N; Civera, M; Felipo, V; Garcia-Torres, ML; Jordá, E; Martinez-Valls, J; Molina, I; Montesinos, E; Montoliu, C; Olmo, JA; Ortega, J; Serra, MA; Urios, A; Wassel, A, 2012) |
| "Keloid is a common complication of the wound healing process." | 1.37 | Cell talk: a phenomenon observed in the keloid scar by immunohistochemical study. ( Ayuob, NN; Hajrah, NH; Shaker, SA, 2011) |
| "In the event that a keloid is presented in isolation, chronic osteomyelitis should be considered as a differential diagnosis, and a high index of suspicion is required in order to establish the diagnosis." | 1.37 | Chronic osteomyelitis in the lower extremity predisposing to the unusual formation of keloids. ( Olabanji, JK; Oladele, AO; Orimolade, EA; Yusuf, MB, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (12.70) | 18.7374 |
| 1990's | 1 (1.59) | 18.2507 |
| 2000's | 6 (9.52) | 29.6817 |
| 2010's | 22 (34.92) | 24.3611 |
| 2020's | 26 (41.27) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Abukhalil, MH | 1 |
| Hussein, OE | 1 |
| Aladaileh, SH | 1 |
| Althunibat, OY | 1 |
| Al-Amarat, W | 1 |
| Saghir, SA | 1 |
| Alfwuaires, MA | 1 |
| Algefare, AI | 1 |
| Alanazi, KM | 1 |
| Al-Swailmi, FK | 1 |
| Kamel, EM | 1 |
| Mahmoud, AM | 2 |
| Ajarem, JS | 1 |
| Hegazy, AK | 1 |
| Allam, GA | 1 |
| Allam, AA | 1 |
| Maodaa, SN | 1 |
| Lee, JK | 1 |
| Jung, JS | 1 |
| Park, SH | 3 |
| Sim, YB | 1 |
| Kim, SM | 1 |
| Ha, TS | 1 |
| Suh, HW | 1 |
| Rath, M | 1 |
| Pitiot, A | 1 |
| Kirr, M | 1 |
| Fröhlich, W | 1 |
| Plosnita, B | 1 |
| Schliep, S | 1 |
| Bauerschmitz, J | 1 |
| Baur, AS | 1 |
| Ostalecki, C | 1 |
| Yu, Y | 1 |
| Wu, H | 1 |
| Zhang, Q | 4 |
| Ogawa, R | 7 |
| Fu, S | 1 |
| Zhou, B | 1 |
| Gao, Z | 1 |
| Liu, W | 3 |
| Wu, X | 1 |
| Wang, W | 2 |
| Li, Y | 2 |
| Li, M | 1 |
| Qu, C | 1 |
| Tang, Z | 1 |
| Zhou, Z | 1 |
| Yu, Z | 2 |
| Wang, X | 1 |
| Xin, L | 1 |
| Shi, T | 1 |
| Bacci, S | 1 |
| Tosa, M | 1 |
| Ansai, SI | 1 |
| Xu, Q | 1 |
| Yang, JX | 1 |
| Li, SY | 1 |
| Chen, ML | 1 |
| He, LR | 1 |
| Ud-Din, S | 1 |
| Bayat, A | 3 |
| Huang, C | 3 |
| Lee, SY | 1 |
| Lee, AR | 1 |
| Choi, JW | 1 |
| Lee, CR | 1 |
| Cho, KH | 1 |
| Lee, JH | 1 |
| Cho, ML | 1 |
| Hong, YK | 1 |
| Chang, YH | 1 |
| Lin, YC | 1 |
| Chen, B | 1 |
| Guevara, BEK | 1 |
| Hsu, CK | 1 |
| Zang, MQ | 1 |
| Lin, P | 1 |
| Zhang, G | 1 |
| Li, H | 2 |
| Song, B | 2 |
| Zheng, Y | 1 |
| Chi, H | 1 |
| Zhu, Y | 1 |
| Cui, Z | 1 |
| Chen, L | 1 |
| Chen, G | 1 |
| Gao, B | 1 |
| Du, Y | 1 |
| Li, Z | 1 |
| Zhang, C | 1 |
| Dong, Y | 1 |
| Sha, X | 1 |
| Jiang, M | 1 |
| Yan, J | 1 |
| Zhang, Y | 1 |
| Zhou, YL | 1 |
| Biazus Soares, G | 1 |
| Mahmoud, O | 1 |
| Yosipovitch, G | 1 |
| Domenico, P | 1 |
| Giuliana, C | 1 |
| Daniele, B | 1 |
| Bruno, B | 1 |
| Alessandro, G | 1 |
| Fabrizio, M | 1 |
| Matteo, TC | 1 |
| Claudio, C | 1 |
| Tan, S | 1 |
| Khumalo, N | 1 |
| Niu, X | 1 |
| Lin, X | 1 |
| Chen, X | 1 |
| Xu, S | 1 |
| Huang, Z | 1 |
| Tang, Q | 1 |
| Cao, ZD | 1 |
| Vinaik, R | 1 |
| Barayan, D | 1 |
| Auger, C | 1 |
| Abdullahi, A | 1 |
| Jeschke, MG | 1 |
| Lee, S | 1 |
| Kim, SK | 1 |
| Park, H | 1 |
| Lee, YJ | 1 |
| Lee, KJ | 1 |
| Lee, DG | 1 |
| Kang, H | 1 |
| Kim, JE | 1 |
| Wang, ZC | 1 |
| Zhao, WY | 1 |
| Cao, Y | 1 |
| Liu, YQ | 1 |
| Sun, Q | 1 |
| Shi, P | 1 |
| Cai, JQ | 1 |
| Shen, XZ | 1 |
| Tan, WQ | 1 |
| Lei, JA | 1 |
| Zhou, Y | 1 |
| Qin, ZL | 1 |
| Soares-Lopes, LR | 1 |
| Soares-Lopes, IM | 1 |
| Filho, LL | 1 |
| Alencar, AP | 1 |
| da Silva, BB | 1 |
| Coentro, JQ | 1 |
| Pugliese, E | 1 |
| Hanley, G | 1 |
| Raghunath, M | 1 |
| Zeugolis, DI | 1 |
| Fujita, M | 1 |
| Yamamoto, Y | 1 |
| Jiang, JJ | 1 |
| Atsumi, T | 1 |
| Tanaka, Y | 1 |
| Ohki, T | 1 |
| Murao, N | 1 |
| Funayama, E | 1 |
| Hayashi, T | 1 |
| Osawa, M | 1 |
| Maeda, T | 1 |
| Kamimura, D | 1 |
| Murakami, M | 1 |
| Marneros, AG | 1 |
| Wulff, BC | 1 |
| Wilgus, TA | 1 |
| Munteanu, AD | 1 |
| Bedereag, ŞI | 1 |
| NiŢescu, C | 1 |
| Florescu, IP | 1 |
| Wang, J | 1 |
| Min, P | 1 |
| Grassetti, L | 1 |
| Lazzeri, D | 1 |
| Zhang, YX | 1 |
| Nicoli, F | 1 |
| Innocenti, M | 1 |
| Torresetti, M | 1 |
| Levin, LS | 1 |
| Persichetti, P | 1 |
| Trace, AP | 1 |
| Enos, CW | 1 |
| Mantel, A | 1 |
| Harvey, VM | 1 |
| Zhao, J | 1 |
| Zhong, A | 1 |
| Friedrich, EE | 1 |
| Jia, S | 1 |
| Xie, P | 1 |
| Galiano, RD | 1 |
| Mustoe, TA | 1 |
| Hong, SJ | 1 |
| Yağmur, Ç | 1 |
| Sinan Engin, M | 1 |
| Akaishi, S | 2 |
| Jumper, N | 1 |
| Hodgkinson, T | 1 |
| Paus, R | 1 |
| Bux, S | 1 |
| Madaree, A | 1 |
| Yamaza, T | 1 |
| Kelly, AP | 2 |
| Shi, S | 2 |
| Wang, S | 1 |
| Brown, J | 1 |
| Wang, L | 1 |
| French, SW | 1 |
| Le, AD | 2 |
| Shaker, SA | 1 |
| Ayuob, NN | 1 |
| Hajrah, NH | 1 |
| Orimolade, EA | 1 |
| Olabanji, JK | 1 |
| Oladele, AO | 1 |
| Yusuf, MB | 1 |
| Felipo, V | 1 |
| Urios, A | 1 |
| Montesinos, E | 1 |
| Molina, I | 1 |
| Garcia-Torres, ML | 1 |
| Civera, M | 1 |
| Olmo, JA | 1 |
| Ortega, J | 1 |
| Martinez-Valls, J | 1 |
| Serra, MA | 1 |
| Cassinello, N | 1 |
| Wassel, A | 1 |
| Jordá, E | 1 |
| Montoliu, C | 1 |
| Mofikoya, BO | 1 |
| Adeyemo, WL | 1 |
| Ugburo, AO | 1 |
| Hyakusoku, H | 1 |
| Deng, WN | 1 |
| Wang, CY | 1 |
| Liu, L | 1 |
| Christophe, M | 1 |
| NOBLE, TB | 1 |
| JULESZ, M | 1 |
| TIBOLDI, T | 1 |
| SZALMA, J | 1 |
| LASZLO, I | 1 |
| KOVACS, K | 1 |
| SZARVAS, F | 1 |
| BALAZS, V | 1 |
| FROEHLICH, M | 1 |
| TOTH, I | 1 |
| Wu, Y | 1 |
| Messadi, DV | 1 |
| Akhondzadeh, A | 1 |
| Nguyen, AL | 1 |
| Aghaloo, TL | 1 |
| Bertolami, CN | 1 |
| Smith, FR | 1 |
| Zhivotovskiĭ, BG | 1 |
| Vinnik, LA | 1 |
| Chvapil, M | 1 |
| Koopmann, CF | 1 |
| Fitzpatrick, RE | 1 |
| Nicoletis, C | 1 |
| Bazin, S | 1 |
| Lous, ML | 1 |
| Hassenstein, E | 1 |
| Welsh, RA | 1 |
| Meyer, AT | 1 |
| Leroy, P | 1 |
| Cortese, TA | 1 |
| Dickey, RA | 1 |
18 reviews available for khellin and Inflammation
| Article | Year |
|---|---|
Emerging insights into the immunological aspects of keloids.
Topics: Fibroblasts; Humans; Inflammation; Keloid | 2021 |
Fine Regulation during Wound Healing by Mast Cells, a Physiological Role Not Yet Clarified.
Topics: Cytokines; Humans; Inflammation; Keloid; Mast Cells; Wound Healing | 2022 |
[Research advances on the influence of poor dietary habits on the development of keloids].
Topics: Diet; Feeding Behavior; Humans; Inflammation; Keloid; NF-kappa B; Tumor Necrosis Factor-alpha | 2022 |
Controlling Inflammation Pre-Emptively or at the Time of Cutaneous Injury Optimises Outcome of Skin Scarring.
Topics: Cicatrix, Hypertrophic; Humans; Inflammation; Keloid; Skin; Skin Diseases; Wound Healing | 2022 |
Role of Inflammasomes in Keloids and Hypertrophic Scars-Lessons Learned from Chronic Diabetic Wounds and Skin Fibrosis.
Topics: Cicatrix, Hypertrophic; Diabetes Mellitus; Endothelial Cells; Fibrosis; Humans; Inflammasomes; Infla | 2022 |
Inflammation in Wound Healing and Pathological Scarring.
Topics: Cicatrix, Hypertrophic; Humans; Inflammation; Keloid; Quality of Life; Wound Healing | 2023 |
The Role of Extracellular Matrix in Wound Healing.
Topics: Extracellular Matrix; Humans; Inflammation; Keloid; Skin; Wound Healing | 2023 |
Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies.
Topics: Animals; Chronic Disease; Humans; Inflammation; Keloid; Neoplasms | 2019 |
The Roles of Inflammation in Keloid and Hypertrophic Scars.
Topics: Animals; Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Collagen; Cytokines; Dermatologic Agents; | 2020 |
Current and upcoming therapies to modulate skin scarring and fibrosis.
Topics: Animals; Cicatrix, Hypertrophic; Fibrosis; Humans; Inflammation; Keloid; Skin Diseases | 2019 |
Roles of lipid metabolism in keloid development.
Topics: Cicatrix; Fibroblasts; Humans; Inflammation; Keloid; Lipid Metabolism; Mechanotransduction, Cellular | 2013 |
Mast cell activity in the healing wound: more than meets the eye?
Topics: Animals; Anti-Inflammatory Agents; Humans; Immunity, Innate; Inflammation; Keloid; Mast Cells; Neova | 2013 |
Keloids and Hypertrophic Scars: A Spectrum of Clinical Challenges.
Topics: Adjuvants, Immunologic; Aminoquinolines; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Anti | 2016 |
An overview of biological basis of pathologic scarring.
Topics: Cicatrix; Cytokines; Fibrosis; Humans; Inflammation; Keloid; Skin; Skin Physiological Phenomena; Tra | 2012 |
Elevated vascular endothelial growth factor in keloids: relevance to tissue fibrosis.
Topics: DNA-Binding Proteins; Endothelial Cells; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Hypoxi | 2004 |
Causes of and treatment options for abnormal scar tissue.
Topics: Anti-Inflammatory Agents; Causality; Cicatrix, Hypertrophic; Cryotherapy; Granulation Tissue; Growth | 2005 |
Scar formation: physiology and pathological states.
Topics: Animals; Cicatrix; Collagen; Contracture; Humans; Inflammation; Joint Diseases; Keloid; Lipid Peroxi | 1984 |
[Radiation treatment of benign diseases--indications, results and technic].
Topics: Arthritis; Breast Neoplasms; Dupuytren Contracture; Endocrine System Diseases; Eye Diseases; Female; | 1986 |
1 trial available for khellin and Inflammation
| Article | Year |
|---|---|
Treatment of inflamed hypertrophic scars using intralesional 5-FU.
Topics: Acne Vulgaris; Adult; Aged; Anti-Inflammatory Agents; Antimetabolites; Cicatrix; Female; Fluorouraci | 1999 |
44 other studies available for khellin and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats.
Topics: Adrenergic beta-Agonists; Animals; Inflammation; Isoproterenol; Khellin; Male; Myocardial Infarction | 2021 |
Effect of Visnagin on Altered Steroidogenesis and Spermatogenesis, and Testicular Injury Induced by the Heavy Metal Lead.
Topics: Animals; Dose-Response Relationship, Drug; Inflammation; Khellin; Lead; Male; Molecular Structure; O | 2021 |
Anti-inflammatory effect of visnagin in lipopolysaccharide-stimulated BV-2 microglial cells.
Topics: Ammi; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cytokines; Fruit; Inflammation; K | 2010 |
Multi-Antigen Imaging Reveals Inflammatory DC, ADAM17 and Neprilysin as Effectors in Keloid Formation.
Topics: ADAM17 Protein; Adolescent; Adult; Case-Control Studies; Cells, Cultured; Dendritic Cells; Fibroblas | 2021 |
Important role of mechanical microenvironment on macrophage dysfunction during keloid pathogenesis.
Topics: Humans; Inflammation; Keloid; Macrophages; Wound Healing | 2022 |
The Polygenic Map of Keloid Fibroblasts Reveals Fibrosis-Associated Gene Alterations in Inflammation and Immune Responses.
Topics: Computational Biology; Disease Susceptibility; Fibroblasts; Fibrosis; Gene Expression Profiling; Gen | 2021 |
Secondary Cutaneous Ossification in Keloids of the Lower Abdomen: A Report of Two Cases.
Topics: Abdomen; Endothelial Cells; Humans; Inflammation; Keloid | 2022 |
The role of altered fatty acid in pathological scars and their dermal fibroblasts.
Topics: Cicatrix, Hypertrophic; Fatty Acids; Fibroblasts; Humans; Inflammation; Keloid; Mechanotransduction, | 2022 |
IL-17 Induces Autophagy Dysfunction to Promote Inflammatory Cell Death and Fibrosis in Keloid Fibroblasts
Topics: Autophagy; Cell Death; Fibroblasts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; | 2022 |
[Status of diagnosis and treatment of hypertrophic scar and keloid].
Topics: Cicatrix, Hypertrophic; Humans; Hyperplasia; Inflammation; Keloid; Risk Factors | 2023 |
Revealing the roles of glycosphingolipid metabolism pathway in the development of keloid: a conjoint analysis of single-cell and machine learning.
Topics: Cell Differentiation; Collagen; Humans; Inflammation; Keloid; Lipid Metabolism; Sulfatases | 2023 |
Identification of a potential bioinformatics-based biomarker in keloids and its correlation with immune infiltration.
Topics: Algorithms; Biomarkers; Cell Proliferation; Computational Biology; Humans; Inflammation; Keloid | 2023 |
Pruritus in keloid scars: mechanisms and treatments.
Topics: Cryotherapy; Humans; Inflammation; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Ear keloids: An innovative 3-steps combined treatment.
Topics: Humans; Inflammation; Keloid; Lasers, Gas; Light; Recurrence; Treatment Outcome | 2023 |
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Topics: Actins; Cell Cycle; Cell Movement; Cell Survival; Cells, Cultured; Collagen; Fibroblasts; Humans; In | 2020 |
[Examining the pathogenesis and therapeutic strategy of keloids from the perspective of systemic inflammation].
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Keloid; Treatment Outcome | 2020 |
Regulation of glycolysis and the Warburg effect in wound healing.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Case-Control Studies; Female; Glucos | 2020 |
Contribution of Autophagy-Notch1-Mediated NLRP3 Inflammasome Activation to Chronic Inflammation and Fibrosis in Keloid Fibroblasts.
Topics: Adolescent; Adult; Aged; Autophagy; Chronic Disease; Female; Fibroblasts; Humans; Inflammasomes; Inf | 2020 |
[Research advances on inflammatory responses involved in keloid development].
Topics: Humans; Inflammation; Inflammation Mediators; Keloid | 2021 |
Morphological and morphometric analysis of the effects of intralesional tamoxifen on keloids.
Topics: Biopsy; Collagen; Female; Fibroblasts; Humans; Inflammation; Keloid; Male; Prospective Studies; Sele | 2017 |
NEDD4 Is Involved in Inflammation Development during Keloid Formation.
Topics: Adult; Aged; Alleles; Biomarkers; Cell Line; Child; Female; Fibroblasts; Gene Knockdown Techniques; | 2019 |
A Role for the E3 Ubiquitin Ligase NEDD4 in Keloid Pathogenesis.
Topics: Endosomal Sorting Complexes Required for Transport; Humans; Inflammation; Keloid; Nedd4 Ubiquitin Pr | 2019 |
Anatomopathological findings in scars: comparative study between different specimens.
Topics: Actins; Adult; Apoptosis; Burns; Cicatrix; Cicatrix, Hypertrophic; Collagen; Female; Humans; Inflamm | 2015 |
Preliminary Outcomes of Distal IMAP and SEAP Flaps for the Treatment of Unstable Keloids Subject to Recurrent Inflammation and Infections in the Lower Sternal and Upper Abdominal Areas.
Topics: Abdomen; Adult; Aged; Epigastric Arteries; Female; Humans; Inflammation; Keloid; Male; Mammary Arter | 2015 |
S100A12 Induced in the Epidermis by Reduced Hydration Activates Dermal Fibroblasts and Causes Dermal Fibrosis.
Topics: Animals; Cell Culture Techniques; Cell Line, Tumor; Cicatrix, Hypertrophic; Coculture Techniques; Cu | 2017 |
Can subphysiological cold application be utilized in excessive dermal scarring prophylaxis and treatment?: A promising hypothetical perspective.
Topics: Animals; Burns; Cold Temperature; Cryotherapy; Dogs; Humans; Inflammation; Keloid; Models, Theoretic | 2016 |
Endothelial dysfunction may play a key role in keloid and hypertrophic scar pathogenesis - Keloids and hypertrophic scars may be vascular disorders.
Topics: Adrenal Cortex Hormones; Burns; Cell Movement; Cicatrix, Hypertrophic; Disease Progression; Endothel | 2016 |
Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology.
Topics: Biopsy; Collagen; Epidermis; Epithelial-Mesenchymal Transition; Fibroblasts; Gene Expression Profili | 2017 |
Keloids show regional distribution of proliferative and degenerate connective tissue elements.
Topics: Adolescent; Adult; Cell Proliferation; Child; Collagen; DNA; Extracellular Matrix; Female; Fibroblas | 2010 |
Tumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axis.
Topics: Adult; Animals; Cell Proliferation; Cell Separation; Cytokines; Fibroblasts; Humans; Inflammation; I | 2009 |
Cell talk: a phenomenon observed in the keloid scar by immunohistochemical study.
Topics: Antigens, CD; Cell Communication; Cicatrix; Collagen; Cytokines; Female; Fibroblasts; Humans; Immuno | 2011 |
Chronic osteomyelitis in the lower extremity predisposing to the unusual formation of keloids.
Topics: Ankle; Child; Chronic Disease; Fibula; Humans; Inflammation; Keloid; Lower Extremity; Male; Nigeria; | 2011 |
Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy.
Topics: Adult; Aged; Ammonia; Cognitive Dysfunction; Fatty Liver; Female; Hepatic Encephalopathy; Humans; Hy | 2012 |
Are keloid and hypertrophic scar different forms of the same disorder? A fibroproliferative skin disorder hypothesis based on keloid findings.
Topics: Adult; Cicatrix, Hypertrophic; Collagen; Diagnosis, Differential; Female; Fibrillar Collagens; Fibro | 2014 |
[The mast cell and trauma].
Topics: Burns; Forensic Medicine; Fractures, Bone; Humans; Inflammation; Keloid; Mast Cells; Wound Healing; | 2002 |
[Scarring, a complex phenomenon].
Topics: Cicatrix; Humans; Inflammation; Keloid | 2003 |
The uterus and the products of inflammation: fundal keloid.
Topics: Disease; Female; Humans; Inflammation; Keloid; Uterine Diseases; Uterus | 1959 |
EFFECT OF THYROTROPIC HORMONE ON GRANULATION TISSUE.
Topics: Electrophoresis; Exudates and Transudates; Gonadotropins; Granulation Tissue; Hexosamines; Inflammat | 1964 |
[An inflammation reaction in the postvaccinal keloid scar].
Topics: Adjuvants, Immunologic; Adolescent; BCG Vaccine; Female; Humans; Inflammation; Keloid; Tuberculosis | 2005 |
Clinical and biochemical features of normal, defective, and pathologic scars.
Topics: Cicatrix; Connective Tissue; Glycosaminoglycans; Granulation Tissue; Humans; Hypertrophy; Inflammati | 1977 |
Intracellular collagen fibers. In human mesenchymal tumors and inflammatory states.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Collagen; Female; Fibroma; Fibrosarcoma; Histiocyt | 1967 |
[The use of benzene adhesives in the closure of wounds].
Topics: Benzene Derivatives; Cicatrix; Humans; Inflammation; Keloid; Surgical Procedures, Operative; Tissue | 1973 |
Complications of ear piercing.
Topics: Culture; Cysts; Dermatitis; Ear Diseases; Ear, External; Esthetics; Ethnicity; Female; Humans; Hyper | 1971 |