Page last updated: 2024-10-30

khellin and Hypopigmentation

khellin has been researched along with Hypopigmentation in 12 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Hypopigmentation: A condition caused by a deficiency or a loss of melanin pigmentation in the epidermis, also known as hypomelanosis. Hypopigmentation can be localized or generalized, and may result from genetic defects, trauma, inflammation, or infections.

Research Excerpts

ExcerptRelevanceReference
"This prospective study evaluates an argon gas-based system for the treatment of keloids in a patient population including all Fitzpatrick skin types with a 1-year follow-up."9.19A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy. ( Bulstra, AE; Niessen, FB; van Leeuwen, MC; van Leeuwen, PA, 2014)
"This prospective study evaluates an argon gas-based system for the treatment of keloids in a patient population including all Fitzpatrick skin types with a 1-year follow-up."5.19A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy. ( Bulstra, AE; Niessen, FB; van Leeuwen, MC; van Leeuwen, PA, 2014)
"Different approaches are used aiming to improve these scars, including intralesional corticosteroids, surgery and more recently, laser therapy."2.82Laser therapy for treating hypertrophic and keloid scars. ( da Silva, CA; da Silva, EM; Kuczynski, U; Leszczynski, R; Pinto, ACPN, 2022)
"Intralesional cryotherapy is a novel treatment for keloid scars in which the scar is frozen from inside."2.80Intralesional cryotherapy for treatment of keloid scars: a prospective study. ( Bulstra, AJ; Galindo-Garre, F; Molier, J; Niessen, FB; van der Wal, MBA; van Leeuwen, MCE; van Leeuwen, PAM; van Zuijlen, PPM, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's3 (25.00)29.6817
2010's4 (33.33)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Lubov, JE1
Rohan, CA1
Travers, JB1
Hill, MJ1
Aranda, A1
Leszczynski, R1
da Silva, CA1
Pinto, ACPN1
Kuczynski, U1
da Silva, EM1
Bjorklund, KA1
Fernandez Faith, E1
Adotama, P1
Papac, N1
Alexis, A1
Wysong, A1
Collins, L1
Doong, JC1
Chapman, LW1
Smith, J1
van Leeuwen, MC2
Bulstra, AE2
van Leeuwen, PA2
Niessen, FB3
van Leeuwen, MCE1
van der Wal, MBA1
Bulstra, AJ1
Galindo-Garre, F1
Molier, J1
van Zuijlen, PPM1
van Leeuwen, PAM1
van der Veen, AJ1
Bloem, WB1
Davoodi, P1
Fernandez, JM1
O, SJ1
Raulin, C1
Greve, B1
Warncke, SH1
Gundogan, C1
Har-Shai, Y1
Dujovny, E1
Rohde, E1
Zouboulis, CC1
Kumar, P1
Adolph, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intralesional Cryotherapy With a Argon Gas Based Device for the Treatment of Keloid and Hypertrophic Scars[NCT02063243]33 participants (Actual)Interventional2010-01-31Completed
Intralesional Cryotherapy for Treatment of Keloid Scars: a Prospective Evaluation[NCT01994616]30 participants (Actual)Observational2009-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for khellin and Hypopigmentation

ArticleYear
Laser therapy for treating hypertrophic and keloid scars.
    The Cochrane database of systematic reviews, 2022, 09-26, Volume: 9

    Topics: Adrenal Cortex Hormones; Adult; Aluminum; Atrophy; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Di

2022
Common Dermatologic Procedures and the Associated Complications Unique to Skin of Color.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2021, 03-01, Volume: 47, Issue:3

    Topics: Chemexfoliation; Cosmetic Techniques; Dermatologic Surgical Procedures; Dry Needling; Humans; Hyperp

2021
Postburn sequelae in the pediatric patient: clinical presentations and treatment options.
    The Journal of craniofacial surgery, 2008, Volume: 19, Issue:4

    Topics: Adolescent; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Contracture; Humans; Hypopigment

2008
Hypopigmentation along subcutaneous veins following intrakeloid triamcinolone injection: a case report and review of literature.
    Burns : journal of the International Society for Burn Injuries, 1998, Volume: 24, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents; Burns; Drug Administration Schedule; Female; Follow-Up Studies

1998

Trials

3 trials available for khellin and Hypopigmentation

ArticleYear
A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2014, Volume: 67, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Argon; Cryosurgery; Elasticity; Female; Gases; Humans; H

2014
Intralesional cryotherapy for treatment of keloid scars: a prospective study.
    Plastic and reconstructive surgery, 2015, Volume: 135, Issue:2

    Topics: Adolescent; Adult; Aged; Asian People; Black People; Child; Cryosurgery; Female; Humans; Hypopigment

2015
Comparison of two devices for the treatment of keloid scars with the use of intralesional cryotherapy: An experimental study.
    Cryobiology, 2015, Volume: 71, Issue:1

    Topics: Albinism, Oculocutaneous; Argon; Cryotherapy; Freezing; Humans; Hypopigmentation; Keloid; Nitrogen;

2015

Other Studies

5 other studies available for khellin and Hypopigmentation

ArticleYear
Stellate Hypopigmentation in a Pediatric Patient After Treatment with Intralesionally-Injected Corticosteroid.
    The American journal of case reports, 2022, Jun-20, Volume: 23

    Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Glucocorticoids; Humans; Hypopigmentation; Injecti

2022
Branching hypopigmentation following intralesional corticosteroid injection: Case report and review of the literature.
    Pediatric dermatology, 2020, Volume: 37, Issue:1

    Topics: Child; Glucocorticoids; Humans; Hypopigmentation; Injections, Intralesional; Keloid; Male; Triamcino

2020
Hypopigmentation on the ear.
    Cutis, 2018, Volume: 102, Issue:1

    Topics: Adrenal Cortex Hormones; Diagnosis, Differential; Ear Diseases; Female; Humans; Hypopigmentation; In

2018
[Excimer laser. Treatment of iatrogenic hypopigmentation following skin resurfacing].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:8

    Topics: Aged; Cosmetic Techniques; Female; Follow-Up Studies; Humans; Hypopigmentation; Iatrogenic Disease;

2004
Effect of skin surface temperature on skin pigmentation during contact and intralesional cryosurgery of keloids.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:2

    Topics: Adult; Cryosurgery; Female; Humans; Hypopigmentation; Keloid; Male; Skin Pigmentation; Skin Temperat

2007