Page last updated: 2024-10-30

khellin and Hyperpigmentation

khellin has been researched along with Hyperpigmentation in 16 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Hyperpigmentation: Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.

Research Excerpts

ExcerptRelevanceReference
"Psoriasis is a papulosquamous disorder that causes significant social and psychological trauma to the patient."5.72Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis. ( Attwa, E; Essam, R; Khater, MH; Selim, HM, 2022)
"Keloidal morphea is a rare variant of scleroderma, which often can be clinically confused with keloid or scar formation."2.66Morphea With Keloidal Features: A Case Report and Review of the Literature. ( Ahn, C; Akkurt, ZM; Ibarra, BS; Sangüeza, OP; Yu, D, 2020)
"Random individual scarring may be minimized by a dynamic personalized accompanying scarring."2.53[How to optimize scarring in dermatologic surgery?] ( Amici, JM; Chaussade, V, 2016)
"Once pseudofolliculitis has become established, treatment consists of avoiding shaving and the use of medical treatment similar to that used in acne."2.46[Pseudofolliculitis barbae]. ( Casals, M; Fernández-Chico, N; Ribera, M, 2010)
"Standard treatment for keloids includes combination intralesional therapy with triamcinolone and fluorouracil."1.91Common Dermatologic Conditions in Skin of Color. ( Frazier, WT; Proddutur, S; Swope, K, 2023)
"Psoriasis is a papulosquamous disorder that causes significant social and psychological trauma to the patient."1.72Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis. ( Attwa, E; Essam, R; Khater, MH; Selim, HM, 2022)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's2 (12.50)29.6817
2010's5 (31.25)24.3611
2020's8 (50.00)2.80

Authors

AuthorsStudies
Moravej, H1
Forghanian, A1
Dadkhahfar, S1
Mozafari, N1
Attwa, E1
Khater, MH1
Selim, HM1
Essam, R1
Ludwig, RJ1
von Stebut, E1
Frazier, WT1
Proddutur, S1
Swope, K1
Yu, D1
Ibarra, BS1
Akkurt, ZM1
Ahn, C1
Sangüeza, OP1
Ismail, SA1
Mohammed, NHK1
Sotohy, M1
Abou-Taleb, DAE1
Li, L2
Yuan, C1
Zhang, X1
Wang, B1
Yan, Y1
Adotama, P1
Papac, N1
Alexis, A1
Wysong, A1
Collins, L1
Amici, JM1
Chaussade, V1
Salmon, NE1
Roberts, N1
Agnew, K1
Koh, WL1
Lim, SP1
Wadhwa, R1
Priyandoko, D1
Gao, R1
Widodo, N1
Nigam, N1
Ahn, HM1
Yun, CO1
Ando, N1
Mahe, C1
Kaul, SC1
Ribera, M1
Fernández-Chico, N1
Casals, M1
Labandeira, J1
León-Mateos, A1
Suárez-Peñaranda, JM1
Garea, MT1
Toribio, J1
Saray, Y1
Güleç, AT1
Bork, K1
Nagel, C1

Reviews

5 reviews available for khellin and Hyperpigmentation

ArticleYear
[Inflammatory dermatoses in skin of color].
    Dermatologie (Heidelberg, Germany), 2023, Volume: 74, Issue:2

    Topics: Acne Vulgaris; Dermatitis, Atopic; Humans; Hyperpigmentation; Keloid; Psoriasis; Rosacea; Skin Pigme

2023
Morphea With Keloidal Features: A Case Report and Review of the Literature.
    The American Journal of dermatopathology, 2020, Volume: 42, Issue:10

    Topics: Adult; Antibodies, Antinuclear; Biopsy; Diagnosis, Differential; Erythema; Female; Humans; Hyperpigm

2020
Common Dermatologic Procedures and the Associated Complications Unique to Skin of Color.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2021, 03-01, Volume: 47, Issue:3

    Topics: Chemexfoliation; Cosmetic Techniques; Dermatologic Surgical Procedures; Dry Needling; Humans; Hyperp

2021
[How to optimize scarring in dermatologic surgery?]
    Annales de dermatologie et de venereologie, 2016, Volume: 143 Suppl 2

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Cicatrix; Cicatrix, Hypertrophic; Combined Modali

2016
[Pseudofolliculitis barbae].
    Actas dermo-sifiliograficas, 2010, Volume: 101, Issue:9

    Topics: Benzoyl Peroxide; Black People; Cicatrix; Combined Modality Therapy; Dermatologic Agents; Disease Su

2010

Trials

2 trials available for khellin and Hyperpigmentation

ArticleYear
Botulinum toxin type A versus 5-Fluorouracil in treatment of keloid.
    Archives of dermatological research, 2021, Volume: 313, Issue:7

    Topics: Adolescent; Adult; Botulinum Toxins, Type A; Female; Fluorouracil; Follow-Up Studies; Humans; Hyperp

2021
Treatment of keloids and hypertrophic scars with dermojet injections of bleomycin: a preliminary study.
    International journal of dermatology, 2005, Volume: 44, Issue:9

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Bleomycin; Cicatrix, Hypertrophic; Female; Fol

2005

Other Studies

9 other studies available for khellin and Hyperpigmentation

ArticleYear
Intralesional bleomycin versus intralesional triamcinolone in the treatment of keloids and hypertrophic scars.
    Dermatologic therapy, 2022, Volume: 35, Issue:9

    Topics: Bleomycin; Cicatrix, Hypertrophic; Humans; Hyperpigmentation; Injections, Intralesional; Keloid; Pai

2022
Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis.
    Dermatologic therapy, 2022, Volume: 35, Issue:11

    Topics: Drug Therapy, Combination; Fluorouracil; Humans; Hyperpigmentation; Injections, Intralesional; Keloi

2022
Common Dermatologic Conditions in Skin of Color.
    American family physician, 2023, Volume: 107, Issue:1

    Topics: Acne Keloid; Humans; Hyperpigmentation; Keloid; Quality of Life; Skin Pigmentation

2023
Superficial X-ray-induced hyperpigmentation in postoperative keloid radiotherapy: A study of 70 keloids to identify clinical features and risk factors.
    Journal of cosmetic dermatology, 2021, Volume: 20, Issue:9

    Topics: Humans; Hyperpigmentation; Keloid; Risk Factors; Treatment Outcome; X-Rays

2021
Keloid-like morphoea.
    Clinical and experimental dermatology, 2014, Volume: 39, Issue:1

    Topics: Child; Female; Humans; Hyperpigmentation; Keloid; Scleroderma, Localized

2014
Dramatic hyperpigmentation of keloids after intralesional triamcinolone acetonide injection.
    Dermatology online journal, 2015, May-18, Volume: 21, Issue:5

    Topics: Diagnosis, Differential; Female; Glucocorticoids; Humans; Hyperpigmentation; Injections, Intralesion

2015
Stress chaperone mortalin regulates human melanogenesis.
    Cell stress & chaperones, 2016, Volume: 21, Issue:4

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Diglycerides; HSP70 Heat-Shock Proteins; Humans; Hy

2016
Polymorphic fibrosing reaction mimicking keloidal scleroderma but without associated classic scleroderma.
    Dermatology (Basel, Switzerland), 2003, Volume: 207, Issue:2

    Topics: Adult; Female; Fibrosis; Humans; Hyperpigmentation; Keloid; Scleroderma, Localized; Scleroderma, Sys

2003
Long-standing pigmented keloid of the ears induced by electrical torture.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:3 Pt 1

    Topics: Adult; Ear, External; Electric Injuries; Humans; Hyperpigmentation; Keloid; Male; Torture

1997