Page last updated: 2024-10-30

khellin and Fibroid

khellin has been researched along with Fibroid in 15 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Research Excerpts

ExcerptRelevanceReference
"Diseases such as uterine leiomyomata (fibroids and benign tumors of the uterus) and keloids (raised scars) may share common etiology."3.01Uterine leiomyomata and keloids fibrosis origins: a mini-review of fibroproliferative diseases. ( Edwards, TL; Hampton, G; Hellwege, JN; Kim, J; Velez Edwards, DR, 2023)
"The association with uterine leiomyoma was borderline significant in Black women (OR, 1."1.91Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank. ( Barker, JN; Dand, N; McGrath, JA; Onoufriadis, A; Parsons, M; Shaw, TJ; Ung, CY; Warwick, A, 2023)
"Both keloids and fibroids are fibroproliferative conditions that have been reported to be more prevalent among Blacks than Whites, and they share similar fibrotic tissue structures, including extracellular matrix composition, gene expression, and protein profiles."1.91Keloids, hypertrophic scars, and uterine fibroid development: a prospective ultrasound study of Black and African American women. ( Baird, DD; Gerety, M; Harmon, QE; Langton, CR, 2023)
"Pilar leiomyoma is the most common subtype originating from arrector pili muscles of pilosebaceous unit."1.56Cutaneous Leiomyoma Mimicking a Keloid. ( Arık, D; Boyuk, E; Saracoğlu, ZN, 2020)
"A 43-year-old man developed an abnormal scar 6 months following excision of a leiomyoma from his left shoulder."1.48Delayed diagnosis of dermal leiomyosarcoma mimicking keloid scar. ( Clinton, A; Herbert, K; Sleiwah, A, 2018)
"Keloids is a fibroproliferative disease."1.40Keloid incidence in Asian people and its comorbidity with other fibrosis-related diseases: a nationwide population-based study. ( Lee, YC; Sun, LM; Wang, KH, 2014)
"Our analysis indicates that uterine fibroids and keloid scars contain higher amounts of glycosaminoglycans relative to normal myometrium and normal adult skin respectively."1.38Proteoglycans of uterine fibroids and keloid scars: similarity in their proteoglycan composition. ( Barker, NM; Caplan, AI; Carrino, DA; Hurd, WW; Mesiano, S, 2012)
"Leiomyoma have often been compared to keloids because of their fibrotic characteristic and higher rate of occurrence among African Americans as compared to other ethnic groups."1.34Genomic and proteomic profiling II: comparative assessment of gene expression profiles in leiomyomas, keloids, and surgically-induced scars. ( Chegini, N; Liu, L; Luo, X; Pan, Q, 2007)
"Uterine leiomyomas are prevalent estrogen-responsive clonal tumors, but the specific genetic alterations that contribute to their development have not been elucidated."1.32Reduced dermatopontin expression is a molecular link between uterine leiomyomas and keloids. ( Catherino, WH; Leppert, PC; Nieman, LK; Payson, M; Potlog-Nahari, C; Segars, JH; Stenmark, MH, 2004)
"One hundred and eighty cases of uterine fibroids out of the two hundred treated in a gynaecological unit in a 7-year period are reviewed."1.27Management of uterine fibroids at the University of Benin Teaching Hospital. ( Ihejerika, IJ; Omu, AE; Tabowei, G, 1984)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's1 (6.67)18.2507
2000's3 (20.00)29.6817
2010's5 (33.33)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Ung, CY1
Warwick, A1
Onoufriadis, A1
Barker, JN1
Parsons, M1
McGrath, JA1
Shaw, TJ1
Dand, N1
Langton, CR1
Gerety, M1
Harmon, QE1
Baird, DD1
Hampton, G1
Kim, J1
Edwards, TL1
Hellwege, JN1
Velez Edwards, DR1
Boyuk, E1
Saracoğlu, ZN1
Arık, D1
Sleiwah, A1
Clinton, A1
Herbert, K1
Sun, LM1
Wang, KH1
Lee, YC1
Morariu, SH1
Suciu, M1
Badea, MA1
Vartolomei, MD1
Buicu, CF1
Cotoi, OS1
Eiser, AR1
Carrino, DA1
Mesiano, S1
Barker, NM1
Hurd, WW1
Caplan, AI1
HUMBY, G1
Catherino, WH2
Leppert, PC2
Stenmark, MH1
Payson, M1
Potlog-Nahari, C1
Nieman, LK1
Segars, JH2
Luo, X1
Pan, Q1
Liu, L1
Chegini, N1
Omu, AE1
Ihejerika, IJ1
Tabowei, G1
Mentzel, T1
Calonje, E1
Fletcher, CD1

Reviews

2 reviews available for khellin and Fibroid

ArticleYear
Uterine leiomyomata and keloids fibrosis origins: a mini-review of fibroproliferative diseases.
    American journal of physiology. Cell physiology, 2023, 10-01, Volume: 325, Issue:4

    Topics: Female; Fibrosis; Humans; Keloid; Leiomyoma; Uterus

2023
A new hypothesis about the origin of uterine fibroids based on gene expression profiling with microarrays.
    American journal of obstetrics and gynecology, 2006, Volume: 195, Issue:2

    Topics: Extracellular Matrix; Female; Gene Expression Profiling; Humans; Keloid; Leiomyoma; Oligonucleotide

2006

Other Studies

13 other studies available for khellin and Fibroid

ArticleYear
Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank.
    JAMA dermatology, 2023, 02-01, Volume: 159, Issue:2

    Topics: Biological Specimen Banks; Cicatrix, Hypertrophic; Cohort Studies; Cross-Sectional Studies; Dermatit

2023
Keloids, hypertrophic scars, and uterine fibroid development: a prospective ultrasound study of Black and African American women.
    F&S science, 2023, Volume: 4, Issue:2

    Topics: Adult; Black or African American; Cicatrix, Hypertrophic; Cohort Studies; Female; Humans; Keloid; Le

2023
Cutaneous Leiomyoma Mimicking a Keloid.
    Acta dermatovenerologica Croatica : ADC, 2020, Volume: 28, Issue:2

    Topics: Adult; Biopsy; Diagnosis, Differential; Female; Humans; Keloid; Leiomyoma; Male; Middle Aged; Skin N

2020
Delayed diagnosis of dermal leiomyosarcoma mimicking keloid scar.
    BMJ case reports, 2018, Jan-26, Volume: 2018

    Topics: Adult; Cicatrix; Delayed Diagnosis; Diagnosis, Differential; Humans; Keloid; Leiomyoma; Leiomyosarco

2018
Keloid incidence in Asian people and its comorbidity with other fibrosis-related diseases: a nationwide population-based study.
    Archives of dermatological research, 2014, Volume: 306, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asian People; Child; Child, Preschool; China; Comorbidit

2014
Multiple asymptomatic cutaneous pilar leiomyoma versus spontaneous eruptive keloids - a case report.
    Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2016, Volume: 57, Issue:1

    Topics: Adolescent; Humans; Keloid; Leiomyoma; Male; Skin Neoplasms

2016
Does over-expression of transforming growth factor-beta account for the increased morbidity in African-Americans?: possible clinical study and therapeutic implications.
    Medical hypotheses, 2010, Volume: 75, Issue:5

    Topics: Black People; Female; Glaucoma; Heart Transplantation; Humans; Keloid; Leiomyoma; Male; Sarcoidosis;

2010
Proteoglycans of uterine fibroids and keloid scars: similarity in their proteoglycan composition.
    The Biochemical journal, 2012, Apr-15, Volume: 443, Issue:2

    Topics: Adolescent; Adult; Extracellular Matrix; Female; Humans; Keloid; Leiomyoma; Middle Aged; Proteoglyca

2012
Keloid.
    The West Indian medical journal, 1957, Volume: 6, Issue:2

    Topics: Female; Humans; Keloid; Leiomyoma; Uterine Neoplasms

1957
Reduced dermatopontin expression is a molecular link between uterine leiomyomas and keloids.
    Genes, chromosomes & cancer, 2004, Volume: 40, Issue:3

    Topics: Adult; Carrier Proteins; Cell Adhesion Molecules; Chondroitin Sulfate Proteoglycans; Extracellular M

2004
Genomic and proteomic profiling II: comparative assessment of gene expression profiles in leiomyomas, keloids, and surgically-induced scars.
    Reproductive biology and endocrinology : RB&E, 2007, Aug-24, Volume: 5

    Topics: Adult; Black or African American; Cicatrix; Cluster Analysis; Female; Gene Expression; Gene Expressi

2007
Management of uterine fibroids at the University of Benin Teaching Hospital.
    Tropical doctor, 1984, Volume: 14, Issue:2

    Topics: Adult; Age Factors; Female; Hospitalization; Humans; Hysterectomy; Infertility, Female; Keloid; Leio

1984
Dermatomyofibroma: additional observations on a distinctive cutaneous myofibroblastic tumour with emphasis on differential diagnosis.
    The British journal of dermatology, 1993, Volume: 129, Issue:1

    Topics: Actins; Adolescent; Adult; Diagnosis, Differential; Female; Fibrosarcoma; Humans; Immunohistochemist

1993