Page last updated: 2024-10-30

khellin and Erythema

khellin has been researched along with Erythema in 17 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.

Research Excerpts

ExcerptRelevanceReference
"Keloid is conventionally treated with intra-lesional (IL) triamcinolone, which is highly operator dependent and has its own adverse effects."9.24A Randomized, Single-Blind Trial of Clobetasol Propionate 0.05% Cream Under Silicone Dressing Occlusion Versus Intra-Lesional Triamcinolone for Treatment of Keloid. ( Imran, FH; Ismail, R; Jamil, A; Nor, NM; Shah, SA, 2017)
"Twenty-eight patients with vitiligo were treated with a new photochemotherapeutic regimen using khellin, a furanochromone, as photosensitizer, together with ultraviolet A (UVA) irradiation."7.67Treatment of vitiligo with khellin and ultraviolet A. ( Hönigsmann, H; Ortel, B; Tanew, A, 1988)
"Keloid is conventionally treated with intra-lesional (IL) triamcinolone, which is highly operator dependent and has its own adverse effects."5.24A Randomized, Single-Blind Trial of Clobetasol Propionate 0.05% Cream Under Silicone Dressing Occlusion Versus Intra-Lesional Triamcinolone for Treatment of Keloid. ( Imran, FH; Ismail, R; Jamil, A; Nor, NM; Shah, SA, 2017)
"Twenty-eight patients with vitiligo were treated with a new photochemotherapeutic regimen using khellin, a furanochromone, as photosensitizer, together with ultraviolet A (UVA) irradiation."3.67Treatment of vitiligo with khellin and ultraviolet A. ( Hönigsmann, H; Ortel, B; Tanew, A, 1988)
"Keloidal morphea is a rare variant of scleroderma, which often can be clinically confused with keloid or scar formation."2.66Morphea With Keloidal Features: A Case Report and Review of the Literature. ( Ahn, C; Akkurt, ZM; Ibarra, BS; Sangüeza, OP; Yu, D, 2020)
"Random individual scarring may be minimized by a dynamic personalized accompanying scarring."2.53[How to optimize scarring in dermatologic surgery?] ( Amici, JM; Chaussade, V, 2016)
"Of course, the best treatment for keloids remains prevention."2.47Advances in the treatment of keloids. ( Berman, B; Caperton, CV; Viera, MH, 2011)
"The color of 33 untreated keloids from 30 patients was measured with a narrow-band reflectance colorimeter."1.43Objective Spectrometric Measurement of Keloid Color in the East Asian Population: Pitfalls of Subjective Color Measurements. ( Akaishi, S; Aoki, M; Dohi, T; Hyakusoku, H; Nakao, J; Ogawa, R, 2016)
" Twenty-five lesions were treated with intralesional cryotherapy combined with postoperative silicone gel sheeting (the cryotherapy + silicone group), and 7 keloids were treated with intralesional cryotherapy alone (the cryotherapy group)."1.40Intralesional cryosurgery combined with topical silicone gel sheeting for the treatment of refractory keloids. ( Babic, D; Dunda, S; Eppstein, RJ; Har-Shai, Y; Pallua, N; Stromps, JP, 2014)
"Only mild and transient post treatment erythema was noted as an adverse effect."1.39The use of the 300 microsecond 1064 nm Nd:YAG laser in the treatment of keloids. ( Frey, MK; Kubota, T; Lu, R; Perez, M; Rossi, A; Smith, LA, 2013)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's1 (5.88)18.2507
2000's1 (5.88)29.6817
2010's7 (41.18)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
GRIFFIN, AC1
HAKIM, RE1
KNOX, J1
Ortel, B1
Tanew, A1
Hönigsmann, H1
Bik, L1
Sangers, T1
Greveling, K1
Prens, E1
Haedersdal, M1
van Doorn, M1
Yu, D1
Ibarra, BS1
Akkurt, ZM1
Ahn, C1
Sangüeza, OP1
Falk, H1
Vissing, M1
Wooler, G1
Gehl, J1
Ruccia, F1
Zoccali, G1
Cooper, L1
Rosten, C1
Nduka, C1
Amici, JM1
Chaussade, V1
Elrefaie, AM1
Salem, RM1
Faheem, MH1
Rossi, A1
Lu, R1
Frey, MK1
Kubota, T1
Smith, LA1
Perez, M1
Stromps, JP1
Dunda, S1
Eppstein, RJ1
Babic, D1
Har-Shai, Y1
Pallua, N1
Aoki, M1
Akaishi, S1
Nakao, J1
Dohi, T1
Hyakusoku, H1
Ogawa, R1
Nor, NM1
Ismail, R1
Jamil, A1
Shah, SA1
Imran, FH1
Cassuto, DA1
Scrimali, L1
Siragò, P1
Viera, MH1
Caperton, CV1
Berman, B2
WEBER, G1
RIESE, W1
Mustoe, TA1
Bieley, HC1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Longitudinal, Intraindividual Clinical Study in Keloid With Multimodal Ultrasound Assessment[NCT06034587]34 participants (Actual)Observational2021-07-21Completed
EGF-loaded Chitosan to Facilitate Epithelial Healing And Prevent Scar Formation of Cesarean Wound[NCT04211597]60 participants (Actual)Interventional2017-09-05Completed
Silicone Taping for the Improvement of Abdominal Donor Site Scars Following Autologous Breast Reconstruction; A Randomized, Prospective Controlled Trial[NCT04506255]32 participants (Anticipated)Interventional2020-11-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for khellin and Erythema

ArticleYear
Efficacy and tolerability of intralesional bleomycin in dermatology: A systematic review.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:3

    Topics: Bleomycin; Cicatrix, Hypertrophic; Erythema; Hemangioma; Humans; Injections, Intralesional; Keloid;

2020
Morphea With Keloidal Features: A Case Report and Review of the Literature.
    The American Journal of dermatopathology, 2020, Volume: 42, Issue:10

    Topics: Adult; Antibodies, Antinuclear; Biopsy; Diagnosis, Differential; Erythema; Female; Humans; Hyperpigm

2020
[How to optimize scarring in dermatologic surgery?]
    Annales de dermatologie et de venereologie, 2016, Volume: 143 Suppl 2

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Cicatrix; Cicatrix, Hypertrophic; Combined Modali

2016
Advances in the treatment of keloids.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:5

    Topics: Erythema; Humans; Keloid; Patient Education as Topic; Pruritus; Racial Groups; Skin Pigmentation; Ti

2011
[SKIN LESIONS FOLLOWING VACCINATIONS].
    Deutsche medizinische Wochenschrift (1946), 1963, Sep-27, Volume: 88

    Topics: BCG Vaccine; Dermatology; Diphtheria Toxoid; Erysipelas; Erythema; Keloid; Mycobacterium bovis; Pert

1963
Evolution of silicone therapy and mechanism of action in scar management.
    Aesthetic plastic surgery, 2008, Volume: 32, Issue:1

    Topics: Administration, Topical; Cicatrix, Hypertrophic; Dermatologic Agents; Erythema; Female; Humans; Kelo

2008
Evolution of silicone therapy and mechanism of action in scar management.
    Aesthetic plastic surgery, 2008, Volume: 32, Issue:1

    Topics: Administration, Topical; Cicatrix, Hypertrophic; Dermatologic Agents; Erythema; Female; Humans; Kelo

2008
Evolution of silicone therapy and mechanism of action in scar management.
    Aesthetic plastic surgery, 2008, Volume: 32, Issue:1

    Topics: Administration, Topical; Cicatrix, Hypertrophic; Dermatologic Agents; Erythema; Female; Humans; Kelo

2008
Evolution of silicone therapy and mechanism of action in scar management.
    Aesthetic plastic surgery, 2008, Volume: 32, Issue:1

    Topics: Administration, Topical; Cicatrix, Hypertrophic; Dermatologic Agents; Erythema; Female; Humans; Kelo

2008

Trials

3 trials available for khellin and Erythema

ArticleYear
Calcium Electroporation for Keloids: A First-in-Man Phase I Study.
    Dermatology (Basel, Switzerland), 2021, Volume: 237, Issue:6

    Topics: Adult; Calcium Chloride; Electrochemotherapy; Erythema; Female; Follow-Up Studies; Humans; Keloid; M

2021
A Randomized, Single-Blind Trial of Clobetasol Propionate 0.05% Cream Under Silicone Dressing Occlusion Versus Intra-Lesional Triamcinolone for Treatment of Keloid.
    Clinical drug investigation, 2017, Volume: 37, Issue:3

    Topics: Administration, Topical; Adult; Clobetasol; Erythema; Female; Humans; Keloid; Male; Occlusive Dressi

2017
Treatment of hypertrophic scars and keloids with an LBO laser (532 nm) and silicone gel sheeting.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2010, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Erythema; Female; Humans; Keloid; Low-Level

2010

Other Studies

8 other studies available for khellin and Erythema

ArticleYear
The wave length effect upon erythemal and carcinogenic response in psoralen treated mice.
    The Journal of investigative dermatology, 1958, Volume: 31, Issue:5

    Topics: Animals; Carcinogens; Erythema; Ficusin; Khellin; Mice; Neoplasms; Neoplasms, Experimental; Ultravio

1958
Treatment of vitiligo with khellin and ultraviolet A.
    Journal of the American Academy of Dermatology, 1988, Volume: 18, Issue:4 Pt 1

    Topics: Adolescent; Adult; Child; Erythema; Female; Humans; Khellin; Male; Middle Aged; Photochemotherapy; S

1988
A three-dimensional scar assessment tool for keloid scars: Volume, erythema and melanin quantified.
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2021, Volume: 27, Issue:6

    Topics: Erythema; Humans; Keloid; Melanins

2021
High-resolution ultrasound for keloids and hypertrophic scar assessment.
    Lasers in medical science, 2020, Volume: 35, Issue:2

    Topics: Adolescent; Cicatrix, Hypertrophic; Erythema; Female; Humans; Keloid; Lasers, Solid-State; Male; Reg

2020
The use of the 300 microsecond 1064 nm Nd:YAG laser in the treatment of keloids.
    Journal of drugs in dermatology : JDD, 2013, Volume: 12, Issue:11

    Topics: Adult; Analysis of Variance; Chemotherapy, Adjuvant; Erythema; Glucocorticoids; Humans; Injections,

2013
Intralesional cryosurgery combined with topical silicone gel sheeting for the treatment of refractory keloids.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2014, Volume: 40, Issue:9

    Topics: Administration, Cutaneous; Adult; Combined Modality Therapy; Cryosurgery; Erythema; Female; Humans;

2014
Objective Spectrometric Measurement of Keloid Color in the East Asian Population: Pitfalls of Subjective Color Measurements.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2016, Volume: 83, Issue:4

    Topics: Adolescent; Adult; Asia, Eastern; Asian People; Erythema; Female; Humans; Keloid; Male; Melanins; Mi

2016
Effects of a water-impermeable, non-silicone-based occlusive dressing on keloids.
    Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Aged; Equipment Design; Erythema; Female; Folliculitis; Follow-Up Studies; Humans

1996