khellin has been researched along with Disease Models, Animal in 42 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (7.14) | 18.7374 |
1990's | 3 (7.14) | 18.2507 |
2000's | 8 (19.05) | 29.6817 |
2010's | 20 (47.62) | 24.3611 |
2020's | 8 (19.05) | 2.80 |
Authors | Studies |
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Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Anchi, P; Annaldas, S; Aslam Saifi, M; Godugu, C; Khurana, A; Pasari, LP | 1 |
Butterweck, V; Chow, N; Khan, SR; Vanachayangkul, P | 1 |
Dai, X; Li, C; Li, Y; Liu, L; Yuan, R | 1 |
Almudéver, P; Alonso-Carpio, M; Cortijo, J; Marín, S; Milara, J; Montero, P; Peiró, T; Ribera, P; Roger, I | 1 |
Cho, ML; Choi, JW; Lee, AR; Lee, JH; Lee, SY; Na, HS; Um, IG | 1 |
Ahmad, N; Cai, J; Chen, Q; Guo, R; Hui, Q; Li, W; Wang, X; Wang, Z; Yang, R; Yang, X; Zhou, Q | 1 |
Chen, AD; Chen, RF; Huang, YT; Kuo, YR; Lai, CS; Li, YT; Lin, SD | 1 |
Chen, X; Cui, X; Wu, X; Xu, P; Yang, S; Yao, X; Zhu, J; Zhu, W | 1 |
Ding, J; Guan, Z; Jing, M; Li, Y; Tang, Z; Zhai, X | 1 |
Bayat, A; Ud-Din, S; Wilgus, TA | 1 |
Choi, MH; Ha, JH; Kim, J; Park, JU | 1 |
Chen, C; Li, F; Luo, S; Sun, Z; Wang, H; Xu, X; Zhu, G | 1 |
Bao, B; Fu, K; Li, X; Zheng, X; Zhu, X | 1 |
Bezdjian, A; Caglar, D; Daniel, SJ; Fanous, A; Fanous, N; Lenhart, SF; Mlynarek, A | 1 |
Alp Göksel, B; Çalışkan, E; Fuat Çiçek, A; Gamsızkan, M; Tunca, M; Yürekli, A | 1 |
de Kerckhove, M; Hirano, A; Ikematsu, K; Kashiyama, K; Kawata, T; Kim, S; Komatsu, T; Martin, P; Mori, R; Okamoto, M; Park, S; Shimokawa, I; Tanaka, K | 1 |
Benya, PD; Chiu, WC; Choi, A; Hsu, T; Kim, EW; Kulber, DA; Lee, YS; Sarkozy, H; Tuan, TL | 1 |
Jin, S; Kim, H; Kim, SH; Lee, DW; Lee, JH; Lee, KH; Lee, WJ; Noh, JY; Park, CO; Shin, JU | 1 |
Andrews, JP; Marttala, J; Rosenbloom, J; Uitto, J | 1 |
Chang, CH; Kim, SY; Park, TH; Rah, DK | 1 |
Chuang, SS; Hsiao, YC; Yang, JY; Yang, SY | 1 |
Ogawa, R | 1 |
Blondel, WC; Chassagne, JF; Gisquet, H; Guillemin, F; Latarche, C; Leroux, A; Liu, H; Merlin, JL; Peiffert, D | 1 |
Cen, Y; Chen, JJ; Duan, WQ; Jin, PS; Liu, Y; Wang, HS; Xu, XW; Zhao, S | 1 |
Boyce, ST; Glaser, K; Hahn, JM; McFarland, KL; Supp, DM | 1 |
Amiranashvili, I; Gogilashvili, Q; Imnadze, I; Sukhitashvili, N; Tabaghua, G | 1 |
Andrac-Meyer, L; Bruno, M; Gonnelli, D; Magalon, G; Mordon, S; Philandrianos, C | 1 |
Ikehara, S; Isogai, Z; Matsui, S; Miyachi, Y; Muroga, E; Naitoh, M; Suzuki, S; Utani, A; Yagi, Y | 1 |
Luo, S; Wang, H | 1 |
Luo, SK; Wang, HB | 1 |
Gao, JH; Li, F | 1 |
Cen, Y; Chen, JJ; Jin, PS; Li, JJ; Liu, XX; Liu, Y; Wang, Y; Xu, XW | 1 |
Ansorge, S; Faust, J; Gollnick, HP; Lindenlaub, P; Neubert, K; Reinhold, D; Schultze, B; Simeoni, L; Thielitz, A; Vetter, RW; Wrenger, S | 1 |
Gao, JH; Lu, F | 1 |
Blazek, J; Muehlberger, T; Ottomann, C | 1 |
Hayward, PG; Kim, YJ; Ko, F; Kucukcelebi, A; Polo, M; Robson, MC | 1 |
Arai, N; Hamano, S; Ichikawa, K; Kikuchi, S; Momose, Y; Shibata, N; Sugimoto, C; Suzawa, H; Tazawa, S; Tsuchiya, O | 1 |
Hamano, S; Ichikawa, K; Kikuchi, S; Komatsu, H; Miyata, H; Suzawa, H; Tsuchiya, O; Yamada, K | 1 |
Kischer, CW; Pindur, J; Sheridan, D | 1 |
Bardach, J; Cram, AE; Domayer, M; Estrem, SA | 1 |
Hendricks, L; Kischer, CW; Shetlar, CL; Shetlar, MR | 1 |
2 review(s) available for khellin and Disease Models, Animal
Article | Year |
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A Review of the Evidence for and against a Role for Mast Cells in Cutaneous Scarring and Fibrosis.
Topics: Animals; Biomarkers; Cell Communication; Cicatrix; Cicatrix, Hypertrophic; Disease Models, Animal; Disease Susceptibility; Fibroblasts; Fibrosis; Humans; Keloid; Mast Cells; Mechanotransduction, Cellular | 2020 |
Keloids: Animal models and pathologic equivalents to study tissue fibrosis.
Topics: Animals; Cicatrix, Hypertrophic; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Keloid; Mice; Protein Serine-Threonine Kinases | 2016 |
40 other study(ies) available for khellin and Disease Models, Animal
Article | Year |
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Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction.
Topics: Acute Disease; Ammi; Amylases; Animals; Anti-Inflammatory Agents; Ceruletide; Disease Models, Animal; Dose-Response Relationship, Drug; Khellin; Lipase; Male; Mice; Multiple Organ Failure; NF-E2-Related Factor 2; NF-kappa B; Pancreatitis; Signal Transduction | 2019 |
Prevention of renal crystal deposition by an extract of Ammi visnaga L. and its constituents khellin and visnagin in hyperoxaluric rats.
Topics: Administration, Oral; Ammi; Animals; Calcium Oxalate; Disease Models, Animal; Hyperoxaluria; Khellin; Kidney; Kidney Calculi; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2011 |
Exosomes from miR-29a-modified adipose-derived mesenchymal stem cells reduce excessive scar formation by inhibiting TGF-β2/Smad3 signaling.
Topics: Animals; Cell Line; Cicatrix, Hypertrophic; Disease Models, Animal; Down-Regulation; Exosomes; Fibroblasts; Humans; Keloid; Male; Mesenchymal Stem Cells; Mice; MicroRNAs; Skin; Smad3 Protein; Transforming Growth Factor beta2; Wound Healing | 2021 |
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies.
Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Keloid; Mice; Quality of Life; Scleroderma, Systemic; Skin; Skin Diseases | 2022 |
Establishment of a humanized mouse model of keloid diseases following the migration of patient immune cells to the lesion: Patient-derived keloid xenograft (PDKX) model.
Topics: Animals; Disease Models, Animal; Fibroblasts; Heterografts; Humans; Keloid; Mice; Mice, Inbred NOD; Mice, SCID; Quality of Life | 2023 |
Comparative Analysis of KGF-2 and bFGF in Prevention of Excessive Wound Healing and Scar Formation in a Corneal Alkali Burn Model.
Topics: Alkalies; Animals; Burns, Chemical; Cell Movement; Cell Proliferation; Cells, Cultured; Cornea; Corneal Injuries; Disease Models, Animal; Eye Burns; Fibroblast Growth Factor 10; Fibroblast Growth Factor 2; Keloid; Microscopy, Acoustic; Rats; Wound Healing | 2019 |
Triamcinolone Acetonide Suppresses Keloid Formation Through Enhancing Apoptosis in a Nude Mouse Model.
Topics: Animals; Apoptosis; Disease Models, Animal; In Situ Nick-End Labeling; Injections, Intralesional; Keloid; Mice; Mice, Nude; Triamcinolone Acetonide | 2019 |
Hematoporphyrin monomethyl ether-mediated photodynamic therapy inhibits the growth of keloid graft by promoting fibroblast apoptosis and reducing vessel formation.
Topics: Adult; Animals; Apoptosis; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Fibroblasts; Hematoporphyrins; Humans; Keloid; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Photochemotherapy; Photosensitizing Agents; Young Adult | 2020 |
MicroRNA-21 may be involved in the therapeutic effects of Galla chinensis ointment on keloid.
Topics: Animals; Biomarkers; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fibroblasts; Humans; Immunohistochemistry; Keloid; Male; Mice; MicroRNAs; Models, Biological; Ointments; PTEN Phosphohydrolase | 2020 |
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model.
Topics: Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Fibroblasts; Humans; Keloid; Male; Mice; Mice, SCID; Proto-Oncogene Proteins c-met; Small Molecule Libraries | 2021 |
Three-dimensional poly lactic-co-glycolic acid scaffold containing autologous platelet-rich plasma supports keloid fibroblast growth and contributes to keloid formation in a nude mouse model.
Topics: Adult; Animals; Cells, Cultured; Collagen; Disease Models, Animal; Female; Fibroblasts; Genetic Vectors; Glycolates; Green Fluorescent Proteins; Humans; Keloid; Lentivirus; Luciferases; Male; Mice; Mice, Nude; Platelet-Rich Plasma; Polyesters; Primary Cell Culture; Tissue Engineering; Tissue Scaffolds; Transfection; Young Adult | 2018 |
[ESTABLISHING AN ANIMAL MODEL OF DEFECATION RECONSTRUCTION AFTER SPINAL CORD INJURY IN RATS BY MECHANICAL POLISHING METHOD].
Topics: Animals; Cauda Equina; Defecation; Disease Models, Animal; Epidermis; Female; Humans; Immunohistochemistry; Keloid; Plastic Surgery Procedures; PPAR gamma; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Treatment Outcome | 2016 |
Treatment of Keloid Scars with Botulinum Toxin Type A versus Triamcinolone in an Athymic Nude Mouse Model.
Topics: Acetylcholine Release Inhibitors; Adult; Animals; Botulinum Toxins, Type A; Disease Models, Animal; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Male; Mice; Mice, Nude; Skin Transplantation; Treatment Outcome; Triamcinolone; Young Adult | 2019 |
Cryosurgery to remove perichondrium for the rabbit ear hypertrophic scar model: a simplified method.
Topics: Animals; Cicatrix, Hypertrophic; Cryosurgery; Disease Models, Animal; Keloid; Rabbits; Wound Healing | 2019 |
Reduced FOXO1 expression accelerates skin wound healing and attenuates scarring.
Topics: Animals; Blotting, Western; Cicatrix; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Keloid; Macrophages; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Wound Healing | 2014 |
Keloid-derived, plasma/fibrin-based skin equivalents generate de novo dermal and epidermal pathology of keloid fibrosis in a mouse model.
Topics: Animals; Cells, Cultured; Collagen Type I; Dermis; Disease Models, Animal; Epidermal Cells; Fibrin; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Keloid; Mice; Mice, Nude; Plasminogen Activator Inhibitor 1; Transplantation, Heterologous; Wound Healing | 2016 |
TSLP Is a Potential Initiator of Collagen Synthesis and an Activator of CXCR4/SDF-1 Axis in Keloid Pathogenesis.
Topics: Animals; Blotting, Western; Cells, Cultured; Chemokine CXCL12; Collagen; Cytokines; Disease Models, Animal; Female; Fibroblasts; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Keloid; Mice; Mice, Inbred BALB C; Real-Time Polymerase Chain Reaction; Receptors, CXCR4; Sampling Studies; Thymic Stromal Lymphopoietin | 2016 |
Establishment of Patient-Derived Keloid Xenograft Model.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Fibroblasts; Heterografts; Humans; Keloid; Male; Mice; Mice, Nude; Rats; Rats, Nude; RNA, Messenger; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2016 |
A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study.
Topics: Adolescent; Adult; Animals; Burns; Calcium Channel Blockers; Child; Child, Preschool; Cicatrix; Cicatrix, Hypertrophic; Decorin; Dermatologic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; Glucocorticoids; Humans; Injections, Intradermal; Injections, Intralesional; Interferon alpha-2; Interferon-alpha; Keloid; Matrix Metalloproteinase 13; Mice; Mice, Inbred BALB C; Mice, Nude; Triamcinolone Acetonide; Verapamil; Young Adult | 2017 |
Keloid and hypertrophic scarring may result from a mechanoreceptor or mechanosensitive nociceptor disorder.
Topics: Animals; Cicatrix, Hypertrophic; Disease Models, Animal; Humans; Keloid; Mechanoreceptors; Models, Theoretical; Nociceptors | 2008 |
Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis.
Topics: Animals; Cicatrix, Hypertrophic; Dermoscopy; Disease Models, Animal; Ear, External; Female; Hypertrophy; Immunosuppressive Agents; Injections, Intradermal; Keloid; Rabbits; Spectrum Analysis; Tacrolimus; Wounds and Injuries | 2011 |
Effect of heat shock protein 47 on collagen synthesis of keloid in vivo.
Topics: Adolescent; Adult; Animals; Blotting, Western; Collagen; Disease Models, Animal; Female; Fibroblasts; Follow-Up Studies; Gene Expression Regulation; HSP47 Heat-Shock Proteins; Humans; Keloid; Male; Mice; Mice, Inbred BALB C; Real-Time Polymerase Chain Reaction; RNA, Messenger; Young Adult | 2011 |
Deep and superficial keloid fibroblasts contribute differentially to tissue phenotype in a novel in vivo model of keloid scar.
Topics: Adolescent; Animals; Cells, Cultured; Child; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Female; Fibroblasts; Humans; Keloid; Keratinocytes; Male; Mice; Mice, Nude; Phenotype; Skin Transplantation; Tissue Engineering; Wound Healing | 2012 |
Characterization of oral ulcer and pathological scar in nude mice model.
Topics: Animals; Cicatrix; Disease Models, Animal; Fibrosis; Humans; Hydrochloric Acid; Immunohistochemistry; Keloid; Mice; Mice, Nude; Mouth; Mouth Mucosa; Oral Ulcer | 2012 |
[Establishment of a keloid model by transplanting human keloid onto the backs of nude mice].
Topics: Animals; Disease Models, Animal; Female; Humans; Keloid; Mice; Mice, Nude; Transplantation, Heterologous | 2014 |
An ex vivo model employing keloid-derived cell-seeded collagen sponges for therapy development.
Topics: Adult; Animals; Chondroitin ABC Lyase; Disease Models, Animal; Extracellular Matrix; Female; Fibroblasts; Gene Expression; Glycosaminoglycans; Humans; Interleukin-1beta; Keloid; Male; Mice; Mice, Nude; Primary Cell Culture; Surgical Sponges; Up-Regulation; Versicans | 2013 |
[The research of assembling animal models of keloid employing the method of tissue engineering].
Topics: Adult; Animals; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Humans; Keloid; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Engineering | 2005 |
[Construction of animal models of keloid by tissue engineering].
Topics: Animals; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Humans; Keloid; Mice; Mice, Inbred BALB C; Mice, Nude; Tissue Engineering | 2005 |
[Experimental gene therapy of keloid in vivo using recombinant adenovirus coding for Fas gene with steroid hormone].
Topics: Adenoviridae; Animals; Disease Models, Animal; fas Receptor; Genetic Therapy; Genetic Vectors; Hormones; Keloid; Mice; Mice, Inbred BALB C; Mice, Nude; Transfection; Viral Vaccines | 2007 |
[Replication of pathological scar in nude mice].
Topics: Animals; Cicatrix, Hypertrophic; Disease Models, Animal; Keloid; Mice; Mice, Inbred BALB C; Mice, Nude | 2007 |
Inhibitors of dipeptidyl peptidase IV-like activity mediate antifibrotic effects in normal and keloid-derived skin fibroblasts.
Topics: Actins; Animals; Collagen Type I; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Keloid; Lysine; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrrolidines; Skin; Thiazoles; Transforming Growth Factor beta1 | 2008 |
[Experimental gene therapy of keloid in vivo using recombinant adenovirus carrying Fas gene].
Topics: Adenoviridae; Animals; Disease Models, Animal; fas Receptor; Female; Genetic Therapy; Genetic Vectors; Humans; Keloid; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Transfection | 2007 |
[Pharmacological therapy of keloids in an athymic mouse model].
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Colchicine; Data Interpretation, Statistical; Disease Models, Animal; Glucocorticoids; Histological Techniques; Homozygote; Humans; Immunohistochemistry; Injections, Intraperitoneal; Keloid; Male; Mice; Mice, Nude; Nicardipine; Skin Transplantation; Time Factors; Transplantation, Heterologous; Triamcinolone | 2008 |
An in vivo model of human proliferative scar.
Topics: Animals; Cell Count; Cicatrix, Hypertrophic; Dermatologic Surgical Procedures; Disease Models, Animal; Factor VIII; Humans; Keloid; Male; Mucins; Peptide Fragments; Procollagen; Rats; Rats, Nude; Skin; Skin Transplantation; Surgical Flaps | 1998 |
[Effect of tranilast, an anti-allergic drug, on the human keloid tissues].
Topics: Animals; Cell Division; Cells, Cultured; Collagen; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Histamine H1 Antagonists; Humans; Hydroxyproline; Keloid; Male; Mice; Mice, Inbred BALB C; Mice, Nude; ortho-Aminobenzoates; Tissue Transplantation; Triamcinolone | 1992 |
[Effect of tranilast, an anti-allergic drug, on carrageenin-induced granulation and capillary permeability in rats].
Topics: Adult; Animals; Capillary Permeability; Carrageenan; Cicatrix; Disease Models, Animal; Dose-Response Relationship, Drug; Granulation Tissue; Histamine H1 Antagonists; Humans; Keloid; Male; Neutrophils; ortho-Aminobenzoates; Rats; Rats, Inbred Strains; Superoxides | 1992 |
Use of nude (athymic) mice for the study of hypertrophic scars and keloids: vascular continuity between mouse and implants.
Topics: Anastomosis, Surgical; Animals; Cicatrix; Dermatologic Surgical Procedures; Disease Models, Animal; Hypertrophy; Keloid; Mice; Mice, Nude; Skin Transplantation | 1989 |
Implantation of human keloid into athymic mice.
Topics: Adult; Animals; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Humans; Keloid; Male; Mice; Mice, Nude; Skin Transplantation | 1987 |
The use of athymic nude mice for the study of human keloids.
Topics: Animals; Disease Models, Animal; Glycosaminoglycans; Humans; Keloid; Mice; Mice, Nude | 1985 |