Page last updated: 2024-10-30

khellin and Dermatitis, Atopic

khellin has been researched along with Dermatitis, Atopic in 16 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Research Excerpts

ExcerptRelevanceReference
"The association with uterine leiomyoma was borderline significant in Black women (OR, 1."1.91Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank. ( Barker, JN; Dand, N; McGrath, JA; Onoufriadis, A; Parsons, M; Shaw, TJ; Ung, CY; Warwick, A, 2023)
"The etiology of keloid is largely unknown; however, AD and keloid share inflammatory pathways characterized by T-helper cell 2 cytokines and increased dermal fibroblast activity."1.62The increased prevalence of keloids in atopic dermatitis patients with allergic comorbidities: a nationwide retrospective cohort study. ( Ahn, HJ; Jeong, SJ; Kwon, HE; Shin, MK, 2021)
"Because keloid and atopic dermatitis have overlapping pathophysiological mechanisms, we aimed to evaluate keloid risk in patients with atopic dermatitis."1.48Keloid risk in patients with atopic dermatitis: a nationwide retrospective cohort study in Taiwan. ( Lu, CC; Lu, YY; Wang, QR; Wu, CH; Yu, WW; Zhang, CL; Zhang, L, 2018)
"Keloid was identified in 13 boys and 10 girls, accounting for 0."1.34Prevalence of childhood acne, ephelides, warts, atopic dermatitis, psoriasis, alopecia areata and keloid in Kaohsiung County, Taiwan: a community-based clinical survey. ( Chen, W; Cheng, YW; Lai, CS; Yang, YC, 2007)
"In the childhood population, atopic eczema and tinea capitis were the most frequent dermatoses, comprising 63% of diagnoses recorded."1.30A study of the spectrum of skin disease occurring in a black population in south-east London. ( Child, FJ; Du Vivier, AW; Fuller, LC; Higgins, EM, 1999)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's2 (12.50)18.2507
2000's1 (6.25)29.6817
2010's3 (18.75)24.3611
2020's7 (43.75)2.80

Authors

AuthorsStudies
Tirgan, MH1
Uitto, J1
Guttman-Yassky, E1
Diaz, A1
Pavel, AB1
Tan, K1
He, H1
Xu, H1
Cueto, I1
Krueger, JG1
Kwon, HE1
Ahn, HJ1
Jeong, SJ1
Shin, MK1
Luk, K1
Fakhoury, J1
Ozog, D1
Limmer, EE2
Knowles, A2
Deng, J2
Parthasarathy, V2
Kwatra, SG2
Glass, DA2
Ludwig, RJ1
von Stebut, E1
Ung, CY1
Warwick, A1
Onoufriadis, A1
Barker, JN1
Parsons, M1
McGrath, JA1
Shaw, TJ1
Dand, N1
Lu, YY1
Lu, CC1
Yu, WW1
Zhang, L1
Wang, QR1
Zhang, CL1
Wu, CH1
Guevara, BE1
Dayrit, JF1
Haddad, V1
Zhang, X1
KUHN, BH1
Yang, YC1
Cheng, YW1
Lai, CS1
Chen, W1
Paradisi, M1
Angelo, C1
Conti, G1
Mostaccioli, S1
Cianchini, G1
Atzori, F1
Puddu, P1
Child, FJ1
Fuller, LC1
Higgins, EM1
Du Vivier, AW1
Achten, G1
Bourlond, A1
Haven, E1
Lapière, CM1
Piérard, J1
Reynaers, H1
Groel, JT1

Reviews

2 reviews available for khellin and Dermatitis, Atopic

ArticleYear
[Inflammatory dermatoses in skin of color].
    Dermatologie (Heidelberg, Germany), 2023, Volume: 74, Issue:2

    Topics: Acne Vulgaris; Dermatitis, Atopic; Humans; Hyperpigmentation; Keloid; Psoriasis; Rosacea; Skin Pigme

2023
Genome-wide association study of skin complex diseases.
    Journal of dermatological science, 2012, Volume: 66, Issue:2

    Topics: Alopecia; Carcinoma, Basal Cell; Dermatitis, Atopic; Female; Genetic Predisposition to Disease; Geno

2012

Trials

2 trials available for khellin and Dermatitis, Atopic

ArticleYear
[Bufexamac cream and ointment for the treatment of various dermatoses].
    Dermatologica, 1973, Volume: 146, Issue:1

    Topics: Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Chronic Disease; Clinical Trials as Topic;

1973
Dimethyl sulfoxide as a vehicle for corticosteroids. A comparison with the occlusive dressing technique.
    Archives of dermatology, 1968, Volume: 97, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatitis, Atopic; Dermatitis, Contact; Eczema; F

1968

Other Studies

12 other studies available for khellin and Dermatitis, Atopic

ArticleYear
Lack of efficacy of dupilumab in the treatment of keloid disorder.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2022, Volume: 36, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Dermatitis, Atopic; Humans; Keloid; Treatment Outcome

2022
Response to 'Lack of efficacy of dupilumab in the treatment of keloid disorder' by MH Tirgan and J Uitto.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2022, Volume: 36, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Dermatitis, Atopic; Humans; Keloid

2022
The increased prevalence of keloids in atopic dermatitis patients with allergic comorbidities: a nationwide retrospective cohort study.
    Scientific reports, 2021, 12-08, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Child; Child, Preschool; Comorbidity; Dermatitis, Ato

2021
Nonresponse and Progression of Diffuse Keloids to Dupilumab Therapy.
    Journal of drugs in dermatology : JDD, 2022, Feb-01, Volume: 21, Issue:2

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Cytokines; Dermatitis, Atopic; Disease Progression; F

2022
Atopic dermatitis is associated with an increased risk of keloids: A case-control study.
    Journal of the American Academy of Dermatology, 2023, Volume: 88, Issue:5

    Topics: Case-Control Studies; Dermatitis, Atopic; Eczema; Hand Dermatoses; Humans; Keloid

2023
Atopic dermatitis is associated with an increased risk of keloids: A case-control study.
    Journal of the American Academy of Dermatology, 2023, Volume: 88, Issue:5

    Topics: Case-Control Studies; Dermatitis, Atopic; Eczema; Hand Dermatoses; Humans; Keloid

2023
Atopic dermatitis is associated with an increased risk of keloids: A case-control study.
    Journal of the American Academy of Dermatology, 2023, Volume: 88, Issue:5

    Topics: Case-Control Studies; Dermatitis, Atopic; Eczema; Hand Dermatoses; Humans; Keloid

2023
Atopic dermatitis is associated with an increased risk of keloids: A case-control study.
    Journal of the American Academy of Dermatology, 2023, Volume: 88, Issue:5

    Topics: Case-Control Studies; Dermatitis, Atopic; Eczema; Hand Dermatoses; Humans; Keloid

2023
Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank.
    JAMA dermatology, 2023, 02-01, Volume: 159, Issue:2

    Topics: Biological Specimen Banks; Cicatrix, Hypertrophic; Cohort Studies; Cross-Sectional Studies; Dermatit

2023
Keloid risk in patients with atopic dermatitis: a nationwide retrospective cohort study in Taiwan.
    BMJ open, 2018, 07-18, Volume: 8, Issue:7

    Topics: Adult; Cohort Studies; Dermatitis, Atopic; Female; Humans; Incidence; Keloid; Male; Middle Aged; Mul

2018
Delayed allergic dermatitis presenting as a keloid-like reaction caused by sting from an Indo-Pacific Portuguese man-o'-war (Physalia utriculus).
    Clinical and experimental dermatology, 2017, Volume: 42, Issue:2

    Topics: Animals; Biopsy; Bites and Stings; Dermatitis, Atopic; Humans; Hydrozoa; Keloid; Male; Time Factors;

2017
CLINICAL EVALUATION OF A STEROID-VITAMIN A-ESTROGEN LOTION.
    Journal of the American Medical Women's Association, 1963, Volume: 18

    Topics: Acne Vulgaris; Alopecia Areata; Dermatitis; Dermatitis, Atopic; Dermatology; Estrogens; Humans; Hydr

1963
Prevalence of childhood acne, ephelides, warts, atopic dermatitis, psoriasis, alopecia areata and keloid in Kaohsiung County, Taiwan: a community-based clinical survey.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:5

    Topics: Acne Vulgaris; Alopecia Areata; Chi-Square Distribution; Child; Cross-Sectional Studies; Dermatitis,

2007
Dubowitz syndrome with keloidal lesions.
    Clinical and experimental dermatology, 1994, Volume: 19, Issue:5

    Topics: Abnormalities, Multiple; Child; Dermatitis, Atopic; Facial Expression; Growth Disorders; Humans; Kel

1994
A study of the spectrum of skin disease occurring in a black population in south-east London.
    The British journal of dermatology, 1999, Volume: 141, Issue:3

    Topics: Acne Vulgaris; Acrodermatitis; Adult; Black or African American; Black People; Child; Cohort Studies

1999