Page last updated: 2024-10-30

khellin and Contracture

khellin has been researched along with Contracture in 32 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Contracture: Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.

Research Excerpts

ExcerptRelevanceReference
"A scar contracture is the result of a contractile wound-healing process occurring in a scar that has already been reepithelialized and adequately healed."2.41Scar contractures, hypertrophic scars, and keloids. ( Brissett, AE; Sherris, DA, 2001)
"Polyfibromatosis is a rare fibrosing condition characterized by fibromatosis in different body areas and by keloid formation, and which can be associated with arthropathy and osteolysis."1.39Arthropathy, osteolysis, keloids, relapsing conjunctival pannus and gingival overgrowth: a variant of polyfibromatosis? ( Cinotti, E; Di Maria, E; Faravelli, F; Ferrero, G; Papadia, M; Paparo, F; Rongioletti, F; Traverso, C, 2013)
"Large and multiple keloids are difficult to treat radically and are currently only treatable by multimodal therapies that aim to relieve symptoms."1.36The most current algorithms for the treatment and prevention of hypertrophic scars and keloids. ( Ogawa, R, 2010)
"Hypertrophic scarring and keloids are frequent sequelae following trauma."1.27Pressure garments in the prevention and treatment of keloids. ( Lee, ST; Ng, CL; Wong, KL, 1983)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199012 (37.50)18.7374
1990's7 (21.88)18.2507
2000's5 (15.63)29.6817
2010's7 (21.88)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Zanoteli, E1
Soares, PS1
Silva, AMSD1
Camelo, CG1
Fonseca, ATQSM1
Albuquerque, MAV1
Moreno, CAM1
Lopes Abath Neto, O1
Novo Filho, GM1
Kulikowski, LD1
Reed, UC1
Cinotti, E1
Ferrero, G1
Paparo, F1
Papadia, M1
Faravelli, F1
Rongioletti, F1
Traverso, C1
Di Maria, E1
Cubitt, JJ1
Chesney, A1
Brown, L1
Nguyen, DQ1
Echeverría, C1
Diaz, A1
Suarez, B1
Bevilacqua, JA1
Bonnemann, C1
Bertini, E1
Castiglioni, C1
Berman, B1
Viera, MH1
Amini, S1
Huo, R1
Jones, IS1
Davoodi, P1
Fernandez, JM1
O, SJ1
Heyen, CA1
Delk, PR1
Bull, MJ1
Weaver, DD1
Grishkevich, VM1
Ogawa, R2
Ono, S1
Chung, KC1
Hayashi, H1
Takami, Y1
Hyakusoku, H1
Collins, J1
Foley, AR1
Straub, V1
Bönnemann, CG1
TANZER, RC1
Chvapil, M1
Koopmann, CF1
Surveyer, JA1
Clougherty, DM1
Ng, CL1
Lee, ST1
Wong, KL1
Rintala, AE1
Piironen, J1
Sherris, DA2
Larrabee, WF1
Murakami, CS1
Tredget, EE2
Nedelec, B1
Scott, PG1
Ghahary, A1
Wang, W1
Qian, Y1
Cui, L1
Panje, WR1
Morris, MR1
Brissett, AE1
Nasilowski, W1
Economides, NG1
Ferrell, TH1
Bayley, EW1
Muguti, GI1
Karabaev, KhK1
Tursunov, BS1
Khaĭdarov, GA1
Robitaille, A1
Halpern, D1
Kottke, FJ1
Burrill, C1
Payne, L1
Crockett, DJ1
Ito, E1
Iso, R1
Flowers, RS1
Podilachak, MD1
Podil'chak, EM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Effectiveness in Prevention of Hypertrophic Scars or Keloids Between Silicone Sheet, Silicone Gel and Paper Steri-strip-A Randomised Controlled Trial.[NCT00849004]75 participants (Anticipated)Interventional2009-03-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for khellin and Contracture

ArticleYear
Prevention and management of hypertrophic scars and keloids after burns in children.
    The Journal of craniofacial surgery, 2008, Volume: 19, Issue:4

    Topics: Adolescent; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Contracture; Dermatologic Surgic

2008
Postburn sequelae in the pediatric patient: clinical presentations and treatment options.
    The Journal of craniofacial surgery, 2008, Volume: 19, Issue:4

    Topics: Adolescent; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Contracture; Humans; Hypopigment

2008
Scar formation: physiology and pathological states.
    Otolaryngologic clinics of North America, 1984, Volume: 17, Issue:2

    Topics: Animals; Cicatrix; Collagen; Contracture; Humans; Inflammation; Joint Diseases; Keloid; Lipid Peroxi

1984
Management of scar contractures, hypertrophic scars, and keloids.
    Otolaryngologic clinics of North America, 1995, Volume: 28, Issue:5

    Topics: Cicatrix; Cicatrix, Hypertrophic; Combined Modality Therapy; Contracture; Follow-Up Studies; Humans;

1995
Hypertrophic scars, keloids, and contractures. The cellular and molecular basis for therapy.
    The Surgical clinics of North America, 1997, Volume: 77, Issue:3

    Topics: Adult; Child; Cicatrix, Hypertrophic; Contracture; Cytokines; Female; Fibroblasts; Humans; Interfero

1997
Pathophysiology and treatment of fibroproliferative disorders following thermal injury.
    Annals of the New York Academy of Sciences, 1999, Oct-30, Volume: 888

    Topics: Animals; Burns; Cicatrix, Hypertrophic; Contracture; Humans; Keloid; Wound Healing

1999
Scar contractures, hypertrophic scars, and keloids.
    Facial plastic surgery : FPS, 2001, Volume: 17, Issue:4

    Topics: Adrenal Cortex Hormones; Cicatrix; Cicatrix, Hypertrophic; Contracture; Humans; Injections, Intrales

2001
[Paramount problems in the rehabilitation of severely burned patients].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1975, May-19, Volume: 30, Issue:20

    Topics: Adaptation, Psychological; Adrenergic alpha-Antagonists; Burns; Contracture; Expectorants; Hemodynam

1975
Wound healing in the patient with burns.
    The Nursing clinics of North America, 1990, Volume: 25, Issue:1

    Topics: Bandages; Burns; Cicatrix; Contracture; Humans; Keloid; Nutritional Physiological Phenomena; Skin Tr

1990

Other Studies

23 other studies available for khellin and Contracture

ArticleYear
Clinical features of collagen VI-related dystrophies: A large Brazilian cohort.
    Clinical neurology and neurosurgery, 2020, Volume: 192

    Topics: Adolescent; Adult; Age of Onset; Brazil; Child; Cohort Studies; Collagen Type VI; Contracture; Disea

2020
Arthropathy, osteolysis, keloids, relapsing conjunctival pannus and gingival overgrowth: a variant of polyfibromatosis?
    American journal of medical genetics. Part A, 2013, Volume: 161A, Issue:6

    Topics: Abnormalities, Multiple; Arthrography; Cleft Palate; Comparative Genomic Hybridization; Conjunctival

2013
Evaluating an outreach service for paediatric burns follow up.
    Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:6

    Topics: Adolescent; Aftercare; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Contracture; Cost-Ben

2015
Keloids, Spontaneous or After Minor Skin Injury: Importance of Not Missing Bethlem Myopathy.
    Acta dermato-venereologica, 2017, 02-08, Volume: 97, Issue:2

    Topics: Adolescent; Collagen Type VI; Contracture; Female; Humans; Keloid; Male; Middle Aged; Muscular Dystr

2017
A report of an apparent new genetic syndrome consisting of joint contractures, keloids, large optic cup-to-disc ratio and renal stones.
    American journal of medical genetics. Part A, 2008, Dec-15, Volume: 146A, Issue:24

    Topics: Abnormalities, Multiple; Adult; Child; Contracture; Female; Humans; Joints; Keloid; Kidney Calculi;

2008
Trapeze-flap plasty: effective method for postburn neck contracture elimination.
    Burns : journal of the International Society for Burn Injuries, 2010, Volume: 36, Issue:3

    Topics: Adolescent; Adult; Burns; Child; Contracture; Female; Follow-Up Studies; Humans; Keloid; Male; Middl

2010
The most current algorithms for the treatment and prevention of hypertrophic scars and keloids.
    Plastic and reconstructive surgery, 2010, Volume: 125, Issue:2

    Topics: Adrenal Cortex Hormones; Algorithms; Bandages; Cicatrix, Hypertrophic; Combined Modality Therapy; Co

2010
Application of multidetector-row computed tomography in propeller flap planning.
    Plastic and reconstructive surgery, 2011, Volume: 127, Issue:2

    Topics: Adolescent; Adult; Burns; Contracture; Female; Foot Ulcer; Humans; Keloid; Male; Middle Aged; Plasti

2011
Spontaneous keloid formation in patients with Bethlem myopathy.
    Neurology, 2012, Nov-20, Volume: 79, Issue:21

    Topics: Adult; Contracture; Female; Humans; Keloid; Male; Middle Aged; Muscular Dystrophies

2012
BURN CONTRACTURE OF THE NECK.
    Plastic and reconstructive surgery, 1964, Volume: 33

    Topics: Bandages; Burns; Child; Contracture; Humans; Keloid; Neck; Skin Transplantation; Splints

1964
Burn scars. Fighting the effects.
    The American journal of nursing, 1983, Volume: 83, Issue:5

    Topics: Adult; Bandages; Burns; Child; Cicatrix; Contracture; Cosmetics; Exercise Therapy; Humans; Keloid; P

1983
Pressure garments in the prevention and treatment of keloids.
    Annals of the Academy of Medicine, Singapore, 1983, Volume: 12, Issue:2 Suppl

    Topics: Burns; Cicatrix; Contracture; Follow-Up Studies; Humans; Keloid; Postoperative Complications; Pressu

1983
Secondary reconstructive surgery in burns.
    Annales chirurgiae et gynaecologiae, 1980, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Age Factors; Burns; Child; Child, Preschool; Cicatrix; Contracture; Humans; Keloi

1980
[Determination of intracellular calcium ions in fibroblasts of contractured scar].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 1998, Volume: 12, Issue:6

    Topics: Biological Transport, Active; Calcium; Cells, Cultured; Cicatrix, Hypertrophic; Contracture; Fibrobl

1998
[Plastic reconstructions in the neck area. Superficial soft tissues of the neck: scar revisions].
    Laryngo- rhino- otologie, 2000, Volume: 79, Issue:6

    Topics: Cicatrix; Cicatrix, Hypertrophic; Contracture; Dermabrasion; Esthetics; Humans; Keloid; Neck; Postop

2000
Neck resurfacing with free tram flap.
    Microsurgery, 1992, Volume: 13, Issue:5

    Topics: Adult; Burns; Contracture; Female; Humans; Keloid; Male; Neck; Neck Injuries; Surgical Flaps

1992
Early experience with reconstructive surgery at Mpilo Central Hospital, Zimbabwe.
    Journal of the Royal College of Surgeons of Edinburgh, 1990, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Burns; Child; Contracture; Female; Humans; Keloid; Male; Middle Aged; Pressure Ul

1990
[Late results of the treatment and rehabilitation of children who suffered burns at an early age].
    Klinicheskaia khirurgiia, 1987, Issue:3

    Topics: Burns; Child, Preschool; Cicatrix; Contracture; Follow-Up Studies; Humans; Infant; Keloid; Time Fact

1987
Correction of keloids and finger contractures in burn patients.
    Archives of physical medicine and rehabilitation, 1973, Volume: 54, Issue:11

    Topics: Burns; Child, Preschool; Cicatrix; Clothing; Contracture; Elasticity; Face; Fingers; Humans; Keloid;

1973
Aspects of plastic surgery. Scars.
    British medical journal, 1974, Jun-22, Volume: 2, Issue:5920

    Topics: Cicatrix; Collagen; Contracture; Humans; Hypertrophy; Keloid; Methods; Surgery, Plastic

1974
[Tension reducing incision and grafting for scar contracture at the joints. 1].
    Keisei geka. Plastic & reconstructive surgery, 1967, Volume: 10, Issue:2

    Topics: Adult; Child; Child, Preschool; Cicatrix; Contracture; Female; Humans; Infant; Joints; Keloid; Male;

1967
Unexpected postoperative problems in skin grafting.
    The Surgical clinics of North America, 1970, Volume: 50, Issue:2

    Topics: Cellulitis; Cicatrix; Contracture; Hematoma; Humans; Infections; Keloid; Necrosis; Postoperative Com

1970
[Use of hyaluronidase in clinical practice].
    Klinicheskaia khirurgiia, 1969, Volume: 12

    Topics: Arthritis, Rheumatoid; Contracture; Humans; Hyaluronoglucosaminidase; Keloid; Sinusitis; Tuberculosi

1969