Page last updated: 2024-10-30

khellin and Benign Neoplasms

khellin has been researched along with Benign Neoplasms in 48 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Research Excerpts

ExcerptRelevanceReference
"To clarify the dosimetric characteristics of a real-time variable shape rubber-containing tungsten (STR) bolus in a clinical plan and investigate the efficacy of the STR bolus in photon radiotherapy for keloids and other superficial tumors."8.31Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors. ( Monzen, H; Nakamura, K; Nishimura, Y; Sakai, Y; Tamura, M, 2023)
"To clarify the dosimetric characteristics of a real-time variable shape rubber-containing tungsten (STR) bolus in a clinical plan and investigate the efficacy of the STR bolus in photon radiotherapy for keloids and other superficial tumors."4.31Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors. ( Monzen, H; Nakamura, K; Nishimura, Y; Sakai, Y; Tamura, M, 2023)
"Keloids are fibroproliferative disorders described by excessive growth of fibrotic tissue, which also invades adjacent areas (beyond the original wound borders)."3.01Modelling Keloids Dynamics: A Brief Review and New Mathematical Perspectives. ( Adebayo, OE; Bordas, SPA; Chouly, F; Eftimie, R; Rolin, G; Urcun, S, 2023)
"Keloids are considered as benign fibroproliferative skin tumors growing beyond the site of the original dermal injury."2.61Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies. ( Bayat, A; Khumalo, N; Tan, S, 2019)
"Therefore, tailor made manipulation of cancer stroma can have important therapeutic consequences."2.55How Signaling Molecules Regulate Tumor Microenvironment: Parallels to Wound Repair. ( Fáber, L; Gál, P; Mirossay, A; Mitrengová, P; Mučaji, P; Novák, Š; Smetana, K; Szabo, P; Varinská, L, 2017)
"New approaches to wound/scar therapy are discussed."2.47Mechanisms of pathological scarring: role of myofibroblasts and current developments. ( Billet, F; Coulomb, B; Desmoulière, A; Micallef, L; Sarrazy, V, 2011)
"Khellin was successfully extracted from Ammi visnaga fruits with a recovery percent of 96."1.62Extraction, purification and radioiodination of Khellin as cancer theranostic agent. ( Abdelmonem, IM; Amin, MA; Essa, BM; Sarhan, MO; Selim, AA, 2021)
"Keloid is a skin disease characterized by exaggerated scar formation, excessive fibroblast proliferation, and excessive collagen deposition."1.62Risk of cancer development in patients with keloids. ( Chang, KL; Hong, CH; Lee, CH; Lu, YY; Tu, HP; Wu, CH; Yang, HJ; Yang, KC, 2021)
"Children accounted for 78."1.38Plastic and reconstructive surgery in Zambia: epidemiology of 16 years of practice. ( Bowman, KG; Corlew, DS; Jovic, G, 2012)
"The array of malignant neoplasms does not suggest an etiology or pathogenesis in common."1.28Keloids and neoplasms in the Rubinstein-Taybi syndrome. ( Miller, RW; Rubinstein, JH; Siraganian, PA, 1989)
"Keloids are benign dermal tumors that form during an abnormal wound-healing process in genetically susceptible individuals."1.27Reduced growth-factor requirement of keloid-derived fibroblasts may account for tumor growth. ( Rodríguez-Eaton, S; Russell, JD; Russell, SB; Trupin, JS; Trupin, KM, 1988)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199031 (64.58)18.7374
1990's1 (2.08)18.2507
2000's1 (2.08)29.6817
2010's7 (14.58)24.3611
2020's8 (16.67)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Selim, AA1
Essa, BM1
Abdelmonem, IM1
Amin, MA1
Sarhan, MO1
GRIFFIN, AC1
HAKIM, RE1
KNOX, J1
VERMEL, EM1
TSETLIN, AL1
APFFEL, CA1
Wang, CH1
Shan, MJ1
Liu, H1
Hao, Y1
Song, KX1
Wu, HW1
Meng, T1
Feng, C1
Qi, Z1
Wang, Z1
Wang, YB1
Su, Z1
Jiao, H1
Sakai, Y2
Monzen, H2
Tamura, M2
Nakamura, K2
Nishimura, Y2
Bensa, T1
Tekkela, S1
Rognoni, E1
Eftimie, R1
Rolin, G1
Adebayo, OE1
Urcun, S1
Chouly, F1
Bordas, SPA1
Tan, S1
Khumalo, N1
Bayat, A1
Jia, CY1
Chen, LX1
Lu, YY1
Tu, HP1
Wu, CH1
Hong, CH1
Yang, KC1
Yang, HJ1
Chang, KL1
Lee, CH1
Rengeng, L1
Qianyu, Z1
Yuehong, L1
Zhongzhong, P1
Libo, L1
Gál, P1
Varinská, L1
Fáber, L1
Novák, Š1
Szabo, P1
Mitrengová, P1
Mirossay, A1
Mučaji, P1
Smetana, K1
Zhao, MJ1
Chen, SY1
Qu, XY1
Abdul-Fattah, B1
Lai, T1
Xie, M1
Wu, SD1
Zhou, YW1
Huang, CZ1
Cai, JL1
Jovic, G1
Corlew, DS1
Bowman, KG1
Sarrazy, V1
Billet, F1
Micallef, L1
Coulomb, B1
Desmoulière, A1
DESFORGES, JA1
LUCCHELLI, P1
MADERNA, C1
CHYTILOVA, M1
KULHANEK, V1
HORN, V1
DE STEFANO, C1
ADAMS, WS1
HARGREAVES, A1
FUJITA, H1
CROCKETT, DJ1
MAJOROS, M1
DEVINE, KD1
PARKHILL, EM1
WOODMAN, EN1
SIELER, H1
BIEMANS, RG1
SCHULZ, MD1
WANG, CC1
CARAYON, A1
RESILLOT, A1
SCHIMPF, A1
HESS, P1
HEINEMANN, L1
PLASCHKES, J1
KAPLAN, I1
RUSSELL, B1
DALICHO, W1
Lemont, H1
Siraganian, PA1
Rubinstein, JH1
Miller, RW1
Russell, SB1
Trupin, KM1
Rodríguez-Eaton, S1
Russell, JD1
Trupin, JS1
Sailer, HF1
Kimura, M1
Schumann, E1
Weiss, E1
Zabolotskiĭ, AT1
Glaser, FH1
Watanabe, T1

Reviews

8 reviews available for khellin and Benign Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Skin fibroblast functional heterogeneity in health and disease.
    The Journal of pathology, 2023, Volume: 260, Issue:5

    Topics: Fibroblasts; Humans; Keloid; Neoplasms; Skin; Wound Healing

2023
Modelling Keloids Dynamics: A Brief Review and New Mathematical Perspectives.
    Bulletin of mathematical biology, 2023, 10-19, Volume: 85, Issue:12

    Topics: Animals; Humans; Keloid; Mathematical Concepts; Models, Biological; Neoplasms; Wound Healing

2023
Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Animals; Chronic Disease; Humans; Inflammation; Keloid; Neoplasms

2019
Sonodynamic therapy, a treatment developing from photodynamic therapy.
    Photodiagnosis and photodynamic therapy, 2017, Volume: 19

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Atherosclerosis; Dendriti

2017
How Signaling Molecules Regulate Tumor Microenvironment: Parallels to Wound Repair.
    Molecules (Basel, Switzerland), 2017, Oct-26, Volume: 22, Issue:11

    Topics: Animals; Cellular Microenvironment; Cytokines; Galectins; Humans; Immune System; Intercellular Signa

2017
Mechanisms of pathological scarring: role of myofibroblasts and current developments.
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2011, Volume: 19 Suppl 1

    Topics: Cicatrix; Cicatrix, Hypertrophic; Granulation Tissue; Humans; Keloid; Liver; Myofibroblasts; Neoplas

2011
[Side reaction following smallpox vaccination].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:4

    Topics: Encephalomyelitis, Acute Disseminated; Exanthema; gamma-Globulins; Humans; Indoles; Keloid; Neoplasm

1971

Other Studies

40 other studies available for khellin and Benign Neoplasms

ArticleYear
Extraction, purification and radioiodination of Khellin as cancer theranostic agent.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2021, Volume: 178

    Topics: Animals; Chromatography, High Pressure Liquid; Humans; Iodine Radioisotopes; Khellin; Male; Mice; Mo

2021
The wave length effect upon erythemal and carcinogenic response in psoralen treated mice.
    The Journal of investigative dermatology, 1958, Volume: 31, Issue:5

    Topics: Animals; Carcinogens; Erythema; Ficusin; Khellin; Mice; Neoplasms; Neoplasms, Experimental; Ultravio

1958
[ON THE ANTINEOPLASTIC ACTIVITY OF SOME FUROCOUMARINS].
    Voprosy onkologii, 1964, Volume: 10

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coumarins; Furans; Furocoumarins; Khellin;

1964
[The cytostatic effects of quinones and of their derivatives; growth inhibition of human tumors with khellin].
    Deutsche medizinische Wochenschrift (1946), 1955, Mar-25, Volume: 80, Issue:12

    Topics: Humans; Khellin; Neoplasms; Quinones

1955
Hyperbaric oxygen treatment on keloid tumor immune gene expression.
    Chinese medical journal, 2021, Sep-13, Volume: 134, Issue:18

    Topics: Gene Expression; Humans; Hyperbaric Oxygenation; Keloid; Neoplasms; Oxygen

2021
Reply: Metabolic reprogramming and Warburg effect in keloids.
    Burns : journal of the International Society for Burn Injuries, 2022, Volume: 48, Issue:5

    Topics: Burns; Cell Proliferation; Humans; Keloid; Neoplasms

2022
Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors.
    Physical and engineering sciences in medicine, 2023, Volume: 46, Issue:1

    Topics: Humans; Keloid; Neoplasms; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Rubber; Tu

2023
Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors.
    Physical and engineering sciences in medicine, 2023, Volume: 46, Issue:1

    Topics: Humans; Keloid; Neoplasms; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Rubber; Tu

2023
Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors.
    Physical and engineering sciences in medicine, 2023, Volume: 46, Issue:1

    Topics: Humans; Keloid; Neoplasms; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Rubber; Tu

2023
Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors.
    Physical and engineering sciences in medicine, 2023, Volume: 46, Issue:1

    Topics: Humans; Keloid; Neoplasms; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Rubber; Tu

2023
[Tumor characteristics of keloid].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2021, Apr-20, Volume: 37, Issue:4

    Topics: Apoptosis; Cicatrix, Hypertrophic; Humans; Keloid; Neoplasms; Skin

2021
Risk of cancer development in patients with keloids.
    Scientific reports, 2021, 04-30, Volume: 11, Issue:1

    Topics: Adult; Case-Control Studies; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Keloid; Mal

2021
Increased Cthrc1 Activates Normal Fibroblasts and Suppresses Keloid Fibroblasts by Inhibiting TGF-β/Smad Signal Pathway and Modulating YAP Subcellular Location.
    Current medical science, 2018, Volume: 38, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Adventitia; Extracellular Matrix Proteins; Fibroblasts; Gene E

2018
[Tumor source theory of keloid occurrence].
    Zhonghua yi xue za zhi, 2009, Apr-28, Volume: 89, Issue:16

    Topics: Humans; Keloid; Neoplasms; Skin

2009
Plastic and reconstructive surgery in Zambia: epidemiology of 16 years of practice.
    World journal of surgery, 2012, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Age Distribution; Child; Child, Preschool; Congenital Abnormalities; Developing C

2012
Non-surgical reduction of granuloma and keloids.
    Journal of the American Podiatry Association, 1958, Volume: 48, Issue:8

    Topics: Fibroma; Foot; Foot Diseases; Granuloma; Humans; Hydrocortisone; Keloid; Neoplasms; Syndrome

1958
[Notes on three cases of perineo-vaginal keloid manifestations].
    Minerva ginecologica, 1958, Jul-31, Volume: 10, Issue:14

    Topics: Female; Fibroma; Humans; Keloid; Medical Records; Neoplasms; Perineum; Vaginal Neoplasms

1958
[Keloids as a form of auto-aggression in the scar].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1960, Volume: 39

    Topics: Aggression; Cicatrix; Fibroma; Humans; Keloid; Neoplasms

1960
Carcinoma with adenomatous structure in skin transplanted in the region of keloid acne of the neck.
    Panminerva medica, 1960, Volume: 2

    Topics: Acne Vulgaris; Carcinoma; Head and Neck Neoplasms; Humans; Keloid; Neoplasms; Skin; Skin Transplanta

1960
A case of tracheal obstruction by an endotracheal keloidal papilloma, following tracheostomy for neonatal laryngeal insufficiency. Excision after five years of tracheostomy life.
    The Journal of laryngology and otology, 1961, Volume: 75

    Topics: Airway Obstruction; Child; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Keloid; Neopl

1961
Dermatological photography.
    East African medical journal, 1963, Volume: 40

    Topics: Africa; Africa, Eastern; Anthrax; Black People; Dermatology; Erythema Multiforme; Herpes Zoster; Hum

1963
Iconographia dermatologica. 10. (Special issue for fibroblastic tumors).
    Hifuka kiyo. Acta dermatologica, 1962, Volume: 57

    Topics: Fibroblasts; Fibroma; Fibrosarcoma; Humans; Keloid; Neoplasms

1962
Colour, cancer, and keloids in the Sudan.
    British journal of plastic surgery, 1962, Volume: 15

    Topics: Black People; Color; Humans; Keloid; Neoplasms; Pigmentation Disorders; Sudan

1962
MALIGNANT TRANSFORMATION OF BENIGN LARYNGEAL PAPILLOMAS IN CHILDREN AFTER RADIATION THERAPY.
    The Surgical clinics of North America, 1963, Volume: 43

    Topics: Carcinoma; Carcinoma, Squamous Cell; Child; Keloid; Laryngeal Neoplasms; Neoplasms; Pathology; Radia

1963
THE TREATMENT OF SKIN CONDITIONS IN THE RADIOTHERAPY DEPARTMENT.
    Radiography, 1963, Volume: 29

    Topics: Acne Vulgaris; Geriatrics; Hair Removal; Humans; Keloid; Keratosis; Neoplasms; Pruritus; Radiotherap

1963
[THE TREATMENT OF BENIGN NEOPLASMS AND HYPERPLASIAS OF THE SKIN WITH CRITICAL OBSERVATIONS ON RADIOTHERAPY].
    Zeitschrift fur arztliche Fortbildung, 1963, Jul-01, Volume: 57

    Topics: Angiokeratoma; Carcinoma, Adenoid Cystic; Dupuytren Contracture; Eosinophilic Granuloma; Epidermal C

1963
A RARE CASE OF SARCOMATOUS DEGENERATION OF A CHELOID.
    Archivum chirurgicum Neerlandicum, 1963, Volume: 15

    Topics: Abdominal Neoplasms; Autopsy; Fibrosarcoma; Humans; Hydrocortisone; Keloid; Neoplasm Metastasis; Neo

1963
RADIOTHERAPY OF LESIONS OF THE LIDS.
    International ophthalmology clinics, 1964, Volume: 4

    Topics: Conjunctiva; Conjunctivitis; Cornea; Eyelashes; Eyelids; Humans; Keloid; Lens, Crystalline; Lymphoma

1964
[SURGICAL TREATMENT OF KELOIDS. SURGERY-RADIOTHERAPY COMBINATION OR "SHAVING OFF"].
    Bulletin de la Societe medicale d'Afrique noire de langue francaise, 1965, Volume: 10

    Topics: Humans; Keloid; Neoplasms; Radiosurgery; Surgical Procedures, Operative

1965
[PRIMARY BLASTOMATOUS RETICULOSIS OF THE SKIN SIMULATING MORPHEA)].
    Archiv fur klinische und experimentelle Dermatologie, 1965, Apr-26, Volume: 222

    Topics: Humans; Keloid; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma; Scalp; S

1965
[RADIOTHERAPY OF NON-AUTHENTIC TUMORS OF THE ECTODERM AND MESODERM].
    Strahlentherapie, 1964, Volume: 124

    Topics: Cicatrix; Ectoderm; Geriatrics; Humans; Keloid; Male; Mesoderm; Neoplasms; Penile Induration; Radiot

1964
[Keloids in the acromial region following BCG vaccination].
    Harefuah, 1962, Feb-15, Volume: 62

    Topics: BCG Vaccine; Humans; Keloid; Mycobacterium bovis; Neoplasms; Scapula; Vaccination

1962
Lymphangioma circumscriptum and keloids.
    The British journal of dermatology, 1951, Volume: 63, Issue:4

    Topics: Hemangioma; Humans; Keloid; Lymphangioma; Neoplasms

1951
For the therapy of the keloids, with special consideration of the radium treatment.
    Strahlentherapie, 1948, Volume: 78, Issue:1

    Topics: Humans; Keloid; Neoplasms

1948
Nodular variety of keloid simulating neoplasia.
    Journal of the American Podiatric Medical Association, 1992, Volume: 82, Issue:8

    Topics: Diagnosis, Differential; Foot Diseases; Humans; Keloid; Neoplasms

1992
Keloids and neoplasms in the Rubinstein-Taybi syndrome.
    Medical and pediatric oncology, 1989, Volume: 17, Issue:6

    Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Female; Humans; Infant; Infant,

1989
Reduced growth-factor requirement of keloid-derived fibroblasts may account for tumor growth.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:2

    Topics: Adult; Cell Division; Cells, Cultured; Cicatrix; DNA Replication; Fibroblasts; Humans; Infant, Newbo

1988
[Prospects in oral pathology and surgery of the masticatory system].
    Schweizerische Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, 1986, Volume: 96 Spec No

    Topics: Bone Diseases; Humans; Keloid; Neoplasms; Oral Surgical Procedures, Preprosthetic; Osteoma, Osteoid;

1986
[Radiotherapy in childhood].
    Zeitschrift fur arztliche Fortbildung, 1968, May-15, Volume: 62, Issue:10

    Topics: Bone Neoplasms; Brain Neoplasms; Child; Hodgkin Disease; Humans; Keloid; Kidney Neoplasms; Leukemia;

1968
Tumours of the soft (mesenchymal) tissues.
    Bulletin of the World Health Organization, 1974, Volume: 50, Issue:1-2

    Topics: Animals; Animals, Domestic; Calcinosis; Cats; Dogs; Histiocytoma, Benign Fibrous; Horses; Keloid; Li

1974
[Elephantiasis (lymphedema) of the extremities of mechanical origin].
    Vestnik khirurgii imeni I. I. Grekova, 1973, Volume: 110, Issue:4

    Topics: Adolescent; Adult; Aneurysm; Arm; Arm Injuries; Cicatrix; Erysipelas; Female; Femoral Artery; Femora

1973
[On the use of dimethyl sulphoxide (DMSO) in radiation therapy (author's transl)].
    Radiobiologia, radiotherapia, 1973, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Child, Preschool; Dimethyl Sulfoxide; Female; Humans; Keloid; Male; Middle Aged;

1973
[Chronogical study on radiotherapy in children. 1. Benign tumors].
    Rinsho hoshasen. Clinical radiography, 1969, Volume: 14, Issue:8

    Topics: Child; Female; Hemangioma; Humans; Japan; Keloid; Male; Neoplasms; Sex Factors; Statistics as Topic;

1969