khellin has been researched along with Angiogenesis, Pathologic in 18 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Keloids are manifestations of abnormal wound repair with unresolved clinical complications." | 1.38 | Altered angiogenic balance in keloids: a key to therapeutic intervention. ( Jayaraman, M; Korrapati, PS; Krishnaswamy, VR; Mogili, NS; Rajaram, R; Venkatraman, A, 2012) |
| "The vessel count of hypertrophic scar, keloid was significantly abundant compared with surgical scar or normal skin (P < 0." | 1.33 | [Relationship between angiogenesis and expression of HO-1 of scar]. ( He, QY; Li, P; Luo, CQ; Peng, H; Zhou, JD; Zhu, J, 2005) |
| "Keloids are tumor-like lesions that result from excessive scar formation during healing of wounds." | 1.33 | Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity. ( Fujiwara, M; Muragaki, Y; Ooshima, A, 2005) |
| "Keloids are a major cause of morbidity, and arise after operation, injury, or cutaneous infection." | 1.32 | Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor. ( Arbiser, JL; Brown, LF; Cohen, C; Gira, AK; Washington, CV, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, L | 1 |
| Fang, Y | 1 |
| Cao, Y | 1 |
| Zhang, R | 1 |
| Wang, X | 1 |
| Huo, R | 1 |
| Wang, F | 1 |
| Lin, L | 1 |
| Li, Q | 1 |
| Wang, Y | 1 |
| Wulff, BC | 1 |
| Wilgus, TA | 1 |
| Zhang, Z | 1 |
| Kang, C | 1 |
| Chen, B | 1 |
| Nie, F | 1 |
| Ma, J | 1 |
| Qin, Z | 1 |
| Gordon, IO | 1 |
| Tretiakova, MS | 1 |
| Noffsinger, AE | 1 |
| Hart, J | 1 |
| Reuter, VE | 1 |
| Al-Ahmadie, HA | 1 |
| Bux, S | 1 |
| Madaree, A | 1 |
| Mahdavian Delavary, B | 1 |
| van der Veer, WM | 1 |
| van Egmond, M | 1 |
| Niessen, FB | 1 |
| Beelen, RH | 1 |
| Blit, PH | 1 |
| Jeschke, MG | 1 |
| Mogili, NS | 1 |
| Krishnaswamy, VR | 1 |
| Jayaraman, M | 1 |
| Rajaram, R | 1 |
| Venkatraman, A | 1 |
| Korrapati, PS | 1 |
| Ammendola, M | 1 |
| Zuccalà, V | 1 |
| Patruno, R | 1 |
| Russo, E | 1 |
| Luposella, M | 1 |
| Amorosi, A | 1 |
| Vescio, G | 1 |
| Sammarco, G | 1 |
| Montemurro, S | 1 |
| De Sarro, G | 1 |
| Sacco, R | 1 |
| Ranieri, G | 1 |
| Amadeu, T | 1 |
| Braune, A | 1 |
| Mandarim-de-Lacerda, C | 1 |
| Porto, LC | 1 |
| Desmoulière, A | 1 |
| Costa, A | 1 |
| Gira, AK | 1 |
| Brown, LF | 1 |
| Washington, CV | 1 |
| Cohen, C | 1 |
| Arbiser, JL | 1 |
| Zhu, J | 1 |
| Luo, CQ | 1 |
| He, QY | 1 |
| Peng, H | 1 |
| Zhou, JD | 1 |
| Li, P | 1 |
| Fujiwara, M | 1 |
| Muragaki, Y | 1 |
| Ooshima, A | 1 |
| Beer, TW | 1 |
| Ong, CT | 1 |
| Khoo, YT | 1 |
| Tan, EK | 1 |
| Mukhopadhyay, A | 1 |
| Do, DV | 1 |
| Han, HC | 1 |
| Lim, IJ | 1 |
| Phan, TT | 1 |
| Zhang, GY | 1 |
| Yi, CG | 1 |
| Li, X | 1 |
| Zheng, Y | 1 |
| Niu, ZG | 1 |
| Xia, W | 1 |
| Meng, Z | 1 |
| Meng, CY | 1 |
| Guo, SZ | 1 |
| Lametschwandtner, A | 1 |
| Staindl, O | 1 |
2 reviews available for khellin and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Mast cell activity in the healing wound: more than meets the eye?
Topics: Animals; Anti-Inflammatory Agents; Humans; Immunity, Innate; Inflammation; Keloid; Mast Cells; Neova | 2013 |
Macrophages in skin injury and repair.
Topics: Animals; Antigen Presentation; Cell Proliferation; Cicatrix, Hypertrophic; Extracellular Matrix Prot | 2011 |
16 other studies available for khellin and Angiogenesis, Pathologic
| Article | Year |
|---|---|
[Advances in the research of treatment of angiogenesis inhibitor on pathological scars].
Topics: Angiogenesis Inhibitors; Cicatrix, Hypertrophic; Collagen; Fibroblasts; Humans; Keloid; Neovasculari | 2017 |
Is survivin a novel pathway for the treatment and pathogenesis of keloid?
Topics: Apoptosis; Cell Proliferation; Gene Expression Regulation; Humans; Inhibitor of Apoptosis Proteins; | 2013 |
[The effects of conditioned medium from keloid fibroblasts under hypoxia on angiogenesis].
Topics: Cell Hypoxia; Cells, Cultured; Culture Media, Conditioned; Fibroblasts; Humans; Keloid; Neovasculari | 2014 |
Prostate-specific membrane antigen expression in regeneration and repair.
Topics: Barrett Esophagus; Blood Vessels; Endometrium; Female; Granulation Tissue; Humans; Immunohistochemis | 2008 |
Keloids show regional distribution of proliferative and degenerate connective tissue elements.
Topics: Adolescent; Adult; Cell Proliferation; Child; Collagen; DNA; Extracellular Matrix; Female; Fibroblas | 2010 |
Keloids: what do we know and what do we do next?
Topics: Angiogenesis Inhibitors; Animals; Endostatins; Female; Humans; Keloid; Male; Neovascularization, Pat | 2012 |
Altered angiogenic balance in keloids: a key to therapeutic intervention.
Topics: Adolescent; Adult; Aged; Angiogenesis Inhibitors; Animals; Case-Control Studies; Child; Collagen Typ | 2012 |
Tryptase-positive mast cells and angiogenesis in keloids: a new possible post-surgical target for prevention.
Topics: Adult; Female; Humans; Keloid; Male; Mast Cells; Middle Aged; Neovascularization, Pathologic; Trypta | 2013 |
Vascularization pattern in hypertrophic scars and keloids: a stereological analysis.
Topics: Actins; Adolescent; Adult; Antigens, CD34; Biomarkers; Child; Child, Preschool; Cicatrix, Hypertroph | 2003 |
Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor.
Topics: Epidermis; Humans; In Situ Hybridization; Keloid; Neovascularization, Pathologic; Vascular Endotheli | 2004 |
[Relationship between angiogenesis and expression of HO-1 of scar].
Topics: Adult; Cicatrix; Cicatrix, Hypertrophic; Female; Heme Oxygenase-1; Humans; Keloid; Male; Middle Aged | 2005 |
Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity.
Topics: Adolescent; Adult; Animals; Antibodies; Blotting, Northern; Cells, Cultured; Endothelium, Vascular; | 2005 |
Keloids are not angiogenic lesions.
Topics: Humans; Keloid; Neovascularization, Pathologic; Vascular Endothelial Growth Factor A | 2005 |
Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Differentiation; Cell Proliferation; Cocult | 2007 |
Inhibition of vascular endothelial growth factor expression in keloid fibroblasts by vector-mediated vascular endothelial growth factor shRNA: a therapeutic potential strategy for keloid.
Topics: Adolescent; Adult; Cells, Cultured; Down-Regulation; Female; Fibroblasts; Genetic Therapy; Genetic V | 2008 |
[Angioarchitecture of keloids. A scanning electron microscopy study of a corrosion specimen].
Topics: Adult; Capillaries; Humans; Keloid; Male; Microscopy, Electron, Scanning; Muscle, Smooth, Vascular; | 1990 |