Page last updated: 2024-10-30

khellin and Angiogenesis, Pathologic

khellin has been researched along with Angiogenesis, Pathologic in 18 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Research Excerpts

ExcerptRelevanceReference
"Keloids are manifestations of abnormal wound repair with unresolved clinical complications."1.38Altered angiogenic balance in keloids: a key to therapeutic intervention. ( Jayaraman, M; Korrapati, PS; Krishnaswamy, VR; Mogili, NS; Rajaram, R; Venkatraman, A, 2012)
"The vessel count of hypertrophic scar, keloid was significantly abundant compared with surgical scar or normal skin (P < 0."1.33[Relationship between angiogenesis and expression of HO-1 of scar]. ( He, QY; Li, P; Luo, CQ; Peng, H; Zhou, JD; Zhu, J, 2005)
"Keloids are tumor-like lesions that result from excessive scar formation during healing of wounds."1.33Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity. ( Fujiwara, M; Muragaki, Y; Ooshima, A, 2005)
"Keloids are a major cause of morbidity, and arise after operation, injury, or cutaneous infection."1.32Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor. ( Arbiser, JL; Brown, LF; Cohen, C; Gira, AK; Washington, CV, 2004)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's8 (44.44)29.6817
2010's9 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dong, L1
Fang, Y1
Cao, Y1
Zhang, R1
Wang, X1
Huo, R1
Wang, F1
Lin, L1
Li, Q1
Wang, Y1
Wulff, BC1
Wilgus, TA1
Zhang, Z1
Kang, C1
Chen, B1
Nie, F1
Ma, J1
Qin, Z1
Gordon, IO1
Tretiakova, MS1
Noffsinger, AE1
Hart, J1
Reuter, VE1
Al-Ahmadie, HA1
Bux, S1
Madaree, A1
Mahdavian Delavary, B1
van der Veer, WM1
van Egmond, M1
Niessen, FB1
Beelen, RH1
Blit, PH1
Jeschke, MG1
Mogili, NS1
Krishnaswamy, VR1
Jayaraman, M1
Rajaram, R1
Venkatraman, A1
Korrapati, PS1
Ammendola, M1
Zuccalà, V1
Patruno, R1
Russo, E1
Luposella, M1
Amorosi, A1
Vescio, G1
Sammarco, G1
Montemurro, S1
De Sarro, G1
Sacco, R1
Ranieri, G1
Amadeu, T1
Braune, A1
Mandarim-de-Lacerda, C1
Porto, LC1
Desmoulière, A1
Costa, A1
Gira, AK1
Brown, LF1
Washington, CV1
Cohen, C1
Arbiser, JL1
Zhu, J1
Luo, CQ1
He, QY1
Peng, H1
Zhou, JD1
Li, P1
Fujiwara, M1
Muragaki, Y1
Ooshima, A1
Beer, TW1
Ong, CT1
Khoo, YT1
Tan, EK1
Mukhopadhyay, A1
Do, DV1
Han, HC1
Lim, IJ1
Phan, TT1
Zhang, GY1
Yi, CG1
Li, X1
Zheng, Y1
Niu, ZG1
Xia, W1
Meng, Z1
Meng, CY1
Guo, SZ1
Lametschwandtner, A1
Staindl, O1

Reviews

2 reviews available for khellin and Angiogenesis, Pathologic

ArticleYear
Mast cell activity in the healing wound: more than meets the eye?
    Experimental dermatology, 2013, Volume: 22, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Humans; Immunity, Innate; Inflammation; Keloid; Mast Cells; Neova

2013
Macrophages in skin injury and repair.
    Immunobiology, 2011, Volume: 216, Issue:7

    Topics: Animals; Antigen Presentation; Cell Proliferation; Cicatrix, Hypertrophic; Extracellular Matrix Prot

2011

Other Studies

16 other studies available for khellin and Angiogenesis, Pathologic

ArticleYear
[Advances in the research of treatment of angiogenesis inhibitor on pathological scars].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2017, Oct-20, Volume: 33, Issue:10

    Topics: Angiogenesis Inhibitors; Cicatrix, Hypertrophic; Collagen; Fibroblasts; Humans; Keloid; Neovasculari

2017
Is survivin a novel pathway for the treatment and pathogenesis of keloid?
    Medical hypotheses, 2013, Volume: 81, Issue:3

    Topics: Apoptosis; Cell Proliferation; Gene Expression Regulation; Humans; Inhibitor of Apoptosis Proteins;

2013
[The effects of conditioned medium from keloid fibroblasts under hypoxia on angiogenesis].
    Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2014, Volume: 30, Issue:4

    Topics: Cell Hypoxia; Cells, Cultured; Culture Media, Conditioned; Fibroblasts; Humans; Keloid; Neovasculari

2014
Prostate-specific membrane antigen expression in regeneration and repair.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2008, Volume: 21, Issue:12

    Topics: Barrett Esophagus; Blood Vessels; Endometrium; Female; Granulation Tissue; Humans; Immunohistochemis

2008
Keloids show regional distribution of proliferative and degenerate connective tissue elements.
    Cells, tissues, organs, 2010, Volume: 191, Issue:3

    Topics: Adolescent; Adult; Cell Proliferation; Child; Collagen; DNA; Extracellular Matrix; Female; Fibroblas

2010
Keloids: what do we know and what do we do next?
    Translational research : the journal of laboratory and clinical medicine, 2012, Volume: 159, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Endostatins; Female; Humans; Keloid; Male; Neovascularization, Pat

2012
Altered angiogenic balance in keloids: a key to therapeutic intervention.
    Translational research : the journal of laboratory and clinical medicine, 2012, Volume: 159, Issue:3

    Topics: Adolescent; Adult; Aged; Angiogenesis Inhibitors; Animals; Case-Control Studies; Child; Collagen Typ

2012
Tryptase-positive mast cells and angiogenesis in keloids: a new possible post-surgical target for prevention.
    Updates in surgery, 2013, Volume: 65, Issue:1

    Topics: Adult; Female; Humans; Keloid; Male; Mast Cells; Middle Aged; Neovascularization, Pathologic; Trypta

2013
Vascularization pattern in hypertrophic scars and keloids: a stereological analysis.
    Pathology, research and practice, 2003, Volume: 199, Issue:7

    Topics: Actins; Adolescent; Adult; Antigens, CD34; Biomarkers; Child; Child, Preschool; Cicatrix, Hypertroph

2003
Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor.
    Journal of the American Academy of Dermatology, 2004, Volume: 50, Issue:6

    Topics: Epidermis; Humans; In Situ Hybridization; Keloid; Neovascularization, Pathologic; Vascular Endotheli

2004
[Relationship between angiogenesis and expression of HO-1 of scar].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2005, Volume: 30, Issue:3

    Topics: Adult; Cicatrix; Cicatrix, Hypertrophic; Female; Heme Oxygenase-1; Humans; Keloid; Male; Middle Aged

2005
Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity.
    Archives of dermatological research, 2005, Volume: 297, Issue:4

    Topics: Adolescent; Adult; Animals; Antibodies; Blotting, Northern; Cells, Cultured; Endothelium, Vascular;

2005
Keloids are not angiogenic lesions.
    Journal of the American Academy of Dermatology, 2005, Volume: 53, Issue:6

    Topics: Humans; Keloid; Neovascularization, Pathologic; Vascular Endothelial Growth Factor A

2005
Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion.
    The Journal of pathology, 2007, Volume: 211, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Differentiation; Cell Proliferation; Cocult

2007
Inhibition of vascular endothelial growth factor expression in keloid fibroblasts by vector-mediated vascular endothelial growth factor shRNA: a therapeutic potential strategy for keloid.
    Archives of dermatological research, 2008, Volume: 300, Issue:4

    Topics: Adolescent; Adult; Cells, Cultured; Down-Regulation; Female; Fibroblasts; Genetic Therapy; Genetic V

2008
[Angioarchitecture of keloids. A scanning electron microscopy study of a corrosion specimen].
    HNO, 1990, Volume: 38, Issue:6

    Topics: Adult; Capillaries; Humans; Keloid; Male; Microscopy, Electron, Scanning; Muscle, Smooth, Vascular;

1990