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ketotifen and Weight Gain

ketotifen has been researched along with Weight Gain in 5 studies

Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"The effect of the testosterone derivative oxymetholone alone or in combination with the H1-receptor antagonist ketotifen, which has recently been shown to block tumour necrosis factor alpha (TNF alpha), on weight gain and performance status in human immunodeficiency virus (HIV) patients with chronic cachexia was evaluated in a 30-week prospective pilot study."9.08Oxymetholone promotes weight gain in patients with advanced human immunodeficiency virus (HIV-1) infection. ( Baumann, M; Brockmeyer, NH; Goos, M; Hengge, UR; Maleba, R, 1996)
" Of the patients who were unable to stop taking theophylline, the Zaditen-and placebo-treated groups recorded average dosage reductions of 62% and 26%, respectively."6.66A Canadian multicenter study with Zaditen (ketotifen) in the treatment of bronchial asthma in children aged 5 to 17 years. ( Brown, CA; Chandra, RK; Ho, P; Hoogerwerf, PE; Kennedy, RJ; Knight, A; Langer, H; Milne, J; Moote, DW; Rackham, A, 1989)
"The effect of the testosterone derivative oxymetholone alone or in combination with the H1-receptor antagonist ketotifen, which has recently been shown to block tumour necrosis factor alpha (TNF alpha), on weight gain and performance status in human immunodeficiency virus (HIV) patients with chronic cachexia was evaluated in a 30-week prospective pilot study."5.08Oxymetholone promotes weight gain in patients with advanced human immunodeficiency virus (HIV-1) infection. ( Baumann, M; Brockmeyer, NH; Goos, M; Hengge, UR; Maleba, R, 1996)
" In the present study, the effects of lime (Citrus aurantifolia) essential oils in reducing body weight, individually and in co-administration with ketotifen, an antihistaminic drug that causes weight gain, has been investigated using a mouse model."3.76Essential oil from Citrus aurantifolia prevents ketotifen-induced weight-gain in mice. ( Asnaashari, S; Delazar, A; Habibi, B; Hamedeyazdan, S; Nahar, L; Sarker, SD; Vasfi, R, 2010)
" Of the patients who were unable to stop taking theophylline, the Zaditen-and placebo-treated groups recorded average dosage reductions of 62% and 26%, respectively."2.66A Canadian multicenter study with Zaditen (ketotifen) in the treatment of bronchial asthma in children aged 5 to 17 years. ( Brown, CA; Chandra, RK; Ho, P; Hoogerwerf, PE; Kennedy, RJ; Knight, A; Langer, H; Milne, J; Moote, DW; Rackham, A, 1989)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asnaashari, S1
Delazar, A1
Habibi, B1
Vasfi, R1
Nahar, L1
Hamedeyazdan, S1
Sarker, SD1
Wang, J1
Shi, GP1
Hengge, UR1
Baumann, M1
Maleba, R1
Brockmeyer, NH1
Goos, M1
Smart, T1
Rackham, A1
Brown, CA1
Chandra, RK1
Ho, P1
Hoogerwerf, PE1
Kennedy, RJ1
Knight, A1
Langer, H1
Milne, J1
Moote, DW1

Trials

2 trials available for ketotifen and Weight Gain

ArticleYear
Oxymetholone promotes weight gain in patients with advanced human immunodeficiency virus (HIV-1) infection.
    The British journal of nutrition, 1996, Volume: 75, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anabolic Agents; Body Mass Index; Cachexia; Drug Therapy,

1996
A Canadian multicenter study with Zaditen (ketotifen) in the treatment of bronchial asthma in children aged 5 to 17 years.
    The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:3

    Topics: Adolescent; Asthma; Bronchospirometry; Canada; Child; Child, Preschool; Clinical Trials as Topic; Do

1989

Other Studies

3 other studies available for ketotifen and Weight Gain

ArticleYear
Essential oil from Citrus aurantifolia prevents ketotifen-induced weight-gain in mice.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:12

    Topics: Animals; Citrus aurantiifolia; Cyclohexenes; Gas Chromatography-Mass Spectrometry; Histamine H1 Anta

2010
Mast cell stabilization: novel medication for obesity and diabetes.
    Diabetes/metabolism research and reviews, 2011, Volume: 27, Issue:8

    Topics: Animals; Cromolyn Sodium; Diabetes Mellitus; Insulin Resistance; Ketotifen; Mast Cells; Mice; Obesit

2011
Other therapies for wasting.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anabolic Agents; Cannabidiol; Dronabinol; Female; Humans; Ketoti

1995