Page last updated: 2024-10-30

ketotifen and Uremia

ketotifen has been researched along with Uremia in 3 studies

Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"This study aims to compare the efficiency of Pregabalin and Ketotifen in treatment of uremic pruritus in hemodialysis (HD) patients."9.51Comparison of Pregabalin and Ketotifen in treatment of uremic pruritus in hemodialysis patients. ( Aflatoonian, M; Azmandian, J; Khalili, M; Khoundabi, B; Mohammadi, S; Mohebbi, A; Mousavi, M; Parsimood, E; Seifi, M; Shamspour, N, 2022)
"A role for histamine in the pathogenesis of uremic pruritus was investigated in maintenance hemodialysis patients."7.68Elevated plasma histamine in chronic uremia. Effects of ketotifen on pruritus. ( Besarab, A; Burke, JF; Francos, GC; Gittlen, SD; Goyal, S; Kauh, YC; Schulman, ES, 1991)
"This study aims to compare the efficiency of Pregabalin and Ketotifen in treatment of uremic pruritus in hemodialysis (HD) patients."5.51Comparison of Pregabalin and Ketotifen in treatment of uremic pruritus in hemodialysis patients. ( Aflatoonian, M; Azmandian, J; Khalili, M; Khoundabi, B; Mohammadi, S; Mohebbi, A; Mousavi, M; Parsimood, E; Seifi, M; Shamspour, N, 2022)
"A role for histamine in the pathogenesis of uremic pruritus was investigated in maintenance hemodialysis patients."3.68Elevated plasma histamine in chronic uremia. Effects of ketotifen on pruritus. ( Besarab, A; Burke, JF; Francos, GC; Gittlen, SD; Goyal, S; Kauh, YC; Schulman, ES, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Shamspour, N1
Aflatoonian, M1
Khalili, M1
Seifi, M1
Mousavi, M1
Azmandian, J1
Mohammadi, S1
Khoundabi, B1
Parsimood, E1
Mohebbi, A1
Tercedor, J1
López-Hernández, B1
Ródenas, JM1
Herranz, MT1
Serrano-Ortega, S1
Francos, GC1
Kauh, YC1
Gittlen, SD1
Schulman, ES1
Besarab, A1
Goyal, S1
Burke, JF1

Trials

1 trial available for ketotifen and Uremia

ArticleYear
Comparison of Pregabalin and Ketotifen in treatment of uremic pruritus in hemodialysis patients.
    Dermatologic therapy, 2022, Volume: 35, Issue:7

    Topics: Humans; Ketotifen; Pregabalin; Pruritus; Quality of Life; Renal Dialysis; Uremia

2022

Other Studies

2 other studies available for ketotifen and Uremia

ArticleYear
Erythropoietin therapy for uremic pruritus.
    The New England journal of medicine, 1992, Sep-03, Volume: 327, Issue:10

    Topics: Erythropoietin; Humans; Ketotifen; Pruritus; Uremia

1992
Elevated plasma histamine in chronic uremia. Effects of ketotifen on pruritus.
    International journal of dermatology, 1991, Volume: 30, Issue:12

    Topics: Chronic Disease; Histamine; Humans; Ketotifen; Mast Cells; Pilot Projects; Pruritus; Renal Dialysis;

1991