ketotifen has been researched along with Substance-Related Disorders in 4 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Substance-Related Disorders: Disorders related to substance use or abuse.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the possible efficacy of ketotifen (K) in the treatment of idiopathic anaphylaxis (IA), K was administered in an open-label trial to six patients with IA who required corticosteroids at doses below which their disease could not be controlled." | 9.06 | Evaluation of ketotifen in corticosteroid-dependent idiopathic anaphylaxis. ( Dykewicz, MS; Harris, KE; Patterson, R; Wong, SS, 1990) |
| "In a multicentre, double-blind trial, the steroid sparing effect of a new anti-anaphylactic agent ketotifen was assessed against placebo in eighty-six steroid-dependent asthmatics." | 7.66 | A steroid sparing effect of ketotifen in steroid-dependent asthmatics. ( Lane, DJ, 1980) |
| "Ketotifen was compared to diazepam to inhibit aversive responding of the mouse in a black and white test box and in the rat social interaction test." | 5.28 | The effect of ketotifen in rodent models of anxiety and on the behavioural consequences of withdrawing from treatment with drugs of abuse. ( Costall, B; Kelly, ME; Naylor, RJ; Onaivi, ES, 1990) |
| "To study the possible efficacy of ketotifen (K) in the treatment of idiopathic anaphylaxis (IA), K was administered in an open-label trial to six patients with IA who required corticosteroids at doses below which their disease could not be controlled." | 5.06 | Evaluation of ketotifen in corticosteroid-dependent idiopathic anaphylaxis. ( Dykewicz, MS; Harris, KE; Patterson, R; Wong, SS, 1990) |
| "In a multicentre, double-blind trial, the steroid sparing effect of a new anti-anaphylactic agent ketotifen was assessed against placebo in eighty-six steroid-dependent asthmatics." | 3.66 | A steroid sparing effect of ketotifen in steroid-dependent asthmatics. ( Lane, DJ, 1980) |
| "Ketotifen was compared to diazepam to inhibit aversive responding of the mouse in a black and white test box and in the rat social interaction test." | 1.28 | The effect of ketotifen in rodent models of anxiety and on the behavioural consequences of withdrawing from treatment with drugs of abuse. ( Costall, B; Kelly, ME; Naylor, RJ; Onaivi, ES, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lane, DJ | 1 |
| Stoloff, RS | 1 |
| Orfan, N | 1 |
| Greenberger, PA | 1 |
| Grammer, LC | 1 |
| Harris, KE | 2 |
| Patterson, R | 2 |
| Dykewicz, MS | 1 |
| Wong, SS | 1 |
| Costall, B | 1 |
| Kelly, ME | 1 |
| Onaivi, ES | 1 |
| Naylor, RJ | 1 |
1 trial available for ketotifen and Substance-Related Disorders
| Article | Year |
|---|---|
Evaluation of ketotifen in corticosteroid-dependent idiopathic anaphylaxis.
Topics: Adult; Anaphylaxis; Angioedema; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Ketotife | 1990 |
3 other studies available for ketotifen and Substance-Related Disorders
| Article | Year |
|---|---|
A steroid sparing effect of ketotifen in steroid-dependent asthmatics.
Topics: Adult; Aged; Anaphylaxis; Asthma; Cromolyn Sodium; Double-Blind Method; Female; Humans; Ketotifen; M | 1980 |
Malignant idiopathic anaphylaxis: three additional cases and extended evaluation.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anaphylaxis; Drug Therapy, Combination; Evaluation Studies as | 1992 |
The effect of ketotifen in rodent models of anxiety and on the behavioural consequences of withdrawing from treatment with drugs of abuse.
Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Operant; Diazepam; Ethanol; Ketotifen; Ma | 1990 |